ATE70056T1 - Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen. - Google Patents

Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen.

Info

Publication number
ATE70056T1
ATE70056T1 AT84110959T AT84110959T ATE70056T1 AT E70056 T1 ATE70056 T1 AT E70056T1 AT 84110959 T AT84110959 T AT 84110959T AT 84110959 T AT84110959 T AT 84110959T AT E70056 T1 ATE70056 T1 AT E70056T1
Authority
AT
Austria
Prior art keywords
sub
derivatives
oxopyrimidin
pharmaceutical preparations
preparations containing
Prior art date
Application number
AT84110959T
Other languages
English (en)
Inventor
Barrie Dr Levitt
Morris Dr Stolar
Original Assignee
Taro Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharma Ind filed Critical Taro Pharma Ind
Application granted granted Critical
Publication of ATE70056T1 publication Critical patent/ATE70056T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT84110959T 1983-09-14 1984-09-13 Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen. ATE70056T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them
EP84110959A EP0137343B1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-Derivate und sie enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
ATE70056T1 true ATE70056T1 (de) 1991-12-15

Family

ID=11054532

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84110959T ATE70056T1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen.

Country Status (10)

Country Link
US (1) US4628056A (de)
EP (1) EP0137343B1 (de)
JP (1) JPH0730044B2 (de)
AT (1) ATE70056T1 (de)
AU (1) AU571265B2 (de)
DE (1) DE3485318D1 (de)
DK (1) DK167615B1 (de)
IE (1) IE58038B1 (de)
IL (1) IL69722A (de)
ZA (1) ZA847274B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223037A1 (de) * 1985-10-24 1987-05-27 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Phenylbarbitursäuren und deren Herstellung
US6093820A (en) * 1997-10-02 2000-07-25 Taro Pharmaceutical Industries Ltd. Method and reagents for N-alkylating ureides
CA2306170A1 (en) * 2000-04-18 2001-10-18 Kenneth Curry Novel amino, carboxy derivatives of barbituric acid
US6939873B2 (en) * 2000-07-26 2005-09-06 Taro Pharmaceuticals Industries Limited Non-sedating barbituric acid derivatives
US7683071B2 (en) * 2000-07-26 2010-03-23 Taro Pharmaceuticals Industries Ltd. Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
IL154060A0 (en) * 2000-07-26 2003-07-31 Taro Pharma Ind Mon-sedating barbiturate compounds as neuroprotective agents
AU2007200460B2 (en) * 2000-07-26 2009-10-08 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
EP1905441A3 (de) * 2000-07-26 2008-04-23 Taro Pharmaceutical Industries Limited Nicht-sedierende Barbituratverbindungen als neuroprotektive Wirkstoffe
US6756379B2 (en) 2001-07-26 2004-06-29 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
CN1291720C (zh) * 2002-01-30 2006-12-27 塔罗制药工业有限公司 非镇静性巴比土酸衍生物
US6810318B2 (en) * 2002-09-13 2004-10-26 General Motors Corporation Drive torque transfer scheme
DE60324703D1 (de) * 2002-12-11 2008-12-24 Taro Pharma Ind Barbitursäure derivaten.
EP1781624A4 (de) 2004-07-02 2010-06-23 Taro Pharma Ind Verfahren zur herstellung von 1-methoxymethyl-5,5-diphenylbarbitursäure
EP1625848A1 (de) * 2004-08-10 2006-02-15 Taro Pharmaceuticals North America, Inc. Zusammensetzung und Verfahren zur verbesserten Abgabe von 5,5-Diphenylbarbitursäure
WO2008066704A2 (en) * 2006-11-14 2008-06-05 Taro Pharmaceuticals North America, Inc. Method of improving bioavailability for non-sedating barbiturates
US9056817B2 (en) * 2011-09-12 2015-06-16 Council Of Scientific And Industrial Research Arylated β-dicarbonyl compounds and process for the preparation thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1960170A (en) * 1934-05-22 Cc - phenylethyl - n -
US3930006A (en) * 1963-04-30 1975-12-30 Aspro Nicholas Ltd Antiparkinsonism compositions and method
US4046894A (en) * 1968-08-05 1977-09-06 Bristol-Myers Company Certain barbituric acid derivatives used as anticonvulsant agents
US3919427A (en) * 1972-06-02 1975-11-11 Kendall & Co Therapeutic compositions containing 1-methyl-3-alkoxymethyl-5,5-disubstituted barbituric acid compounds
US3948896A (en) * 1973-02-28 1976-04-06 The Kendall Company N-mono(alkoxymethyl) phenobarbitals, process therefor and therapeutic composition and method containing same

Also Published As

Publication number Publication date
EP0137343A2 (de) 1985-04-17
IE58038B1 (en) 1993-06-16
IE842332L (en) 1985-03-14
ZA847274B (en) 1986-04-30
EP0137343B1 (de) 1991-12-04
JPS6084272A (ja) 1985-05-13
IL69722A0 (en) 1983-12-30
AU3287584A (en) 1985-03-21
IL69722A (en) 1986-09-30
AU571265B2 (en) 1988-04-14
DK431784D0 (da) 1984-09-11
DK167615B1 (da) 1993-11-29
US4628056A (en) 1986-12-09
DE3485318D1 (de) 1992-01-16
EP0137343A3 (en) 1986-06-11
DK431784A (da) 1985-03-15
JPH0730044B2 (ja) 1995-04-05

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time