IL69722A - Oxopyrimidine derivatives and pharmaceutical compositions containing them - Google Patents

Oxopyrimidine derivatives and pharmaceutical compositions containing them

Info

Publication number
IL69722A
IL69722A IL69722A IL6972283A IL69722A IL 69722 A IL69722 A IL 69722A IL 69722 A IL69722 A IL 69722A IL 6972283 A IL6972283 A IL 6972283A IL 69722 A IL69722 A IL 69722A
Authority
IL
Israel
Prior art keywords
sub
pharmaceutical compositions
compositions containing
hydrogen
compounds
Prior art date
Application number
IL69722A
Other languages
English (en)
Other versions
IL69722A0 (en
Original Assignee
Taro Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharma Ind filed Critical Taro Pharma Ind
Priority to IL69722A priority Critical patent/IL69722A/xx
Publication of IL69722A0 publication Critical patent/IL69722A0/xx
Priority to US06/647,680 priority patent/US4628056A/en
Priority to AU32875/84A priority patent/AU571265B2/en
Priority to DK431784A priority patent/DK167615B1/da
Priority to JP19241384A priority patent/JPH0730044B2/ja
Priority to DE8484110959T priority patent/DE3485318D1/de
Priority to AT84110959T priority patent/ATE70056T1/de
Priority to EP84110959A priority patent/EP0137343B1/de
Priority to IE233284A priority patent/IE58038B1/en
Priority to ZA847274A priority patent/ZA847274B/xx
Publication of IL69722A publication Critical patent/IL69722A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL69722A 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them IL69722A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them
US06/647,680 US4628056A (en) 1983-09-14 1984-09-05 Novel oxopyrimidine derivatives, pharmaceutical compositions containing them and their use as anticonvulsant, antianxiety and muscle relaxant agents
AU32875/84A AU571265B2 (en) 1983-09-14 1984-09-10 Oxopyrimidine derivatives
DK431784A DK167615B1 (da) 1983-09-14 1984-09-11 Barbitursyrederivater og farmaceutiske praeparater indeholdende saadanne
IE233284A IE58038B1 (en) 1983-09-14 1984-09-13 Novel oxopyrimidine derivatives and pharmaceutical compositions containing them
JP19241384A JPH0730044B2 (ja) 1983-09-14 1984-09-13 新規なるオキソピリミジン誘導体
DE8484110959T DE3485318D1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen.
AT84110959T ATE70056T1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen.
EP84110959A EP0137343B1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-Derivate und sie enthaltende pharmazeutische Zubereitungen
ZA847274A ZA847274B (en) 1983-09-14 1984-09-14 Oxopyramidine derivatives and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL69722A0 IL69722A0 (en) 1983-12-30
IL69722A true IL69722A (en) 1986-09-30

Family

ID=11054532

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US4628056A (de)
EP (1) EP0137343B1 (de)
JP (1) JPH0730044B2 (de)
AT (1) ATE70056T1 (de)
AU (1) AU571265B2 (de)
DE (1) DE3485318D1 (de)
DK (1) DK167615B1 (de)
IE (1) IE58038B1 (de)
IL (1) IL69722A (de)
ZA (1) ZA847274B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223037A1 (de) * 1985-10-24 1987-05-27 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Phenylbarbitursäuren und deren Herstellung
US6093820A (en) * 1997-10-02 2000-07-25 Taro Pharmaceutical Industries Ltd. Method and reagents for N-alkylating ureides
CA2306170A1 (en) * 2000-04-18 2001-10-18 Kenneth Curry Novel amino, carboxy derivatives of barbituric acid
AU2007200460B2 (en) * 2000-07-26 2009-10-08 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
US7683071B2 (en) * 2000-07-26 2010-03-23 Taro Pharmaceuticals Industries Ltd. Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
US6756379B2 (en) 2001-07-26 2004-06-29 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
US6939873B2 (en) * 2000-07-26 2005-09-06 Taro Pharmaceuticals Industries Limited Non-sedating barbituric acid derivatives
DE60132337T2 (de) * 2000-07-26 2009-02-12 Taro Pharmaceutical Industries Ltd. Nicht-sedierende barbituratverbindungen als neuroprotektive wirkstoffe
EP1905441A3 (de) * 2000-07-26 2008-04-23 Taro Pharmaceutical Industries Limited Nicht-sedierende Barbituratverbindungen als neuroprotektive Wirkstoffe
CN1291720C (zh) * 2002-01-30 2006-12-27 塔罗制药工业有限公司 非镇静性巴比土酸衍生物
US6810318B2 (en) * 2002-09-13 2004-10-26 General Motors Corporation Drive torque transfer scheme
AR042444A1 (es) * 2002-12-11 2005-06-22 Taro Pharmaceuticals Ireland L Metodo para el tratamiento de desordenes del movimiento mediante la utilizacion de acido barbiturico
CA2572797A1 (en) * 2004-07-02 2006-01-12 Daniella Gutman A process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid
EP1625848A1 (de) * 2004-08-10 2006-02-15 Taro Pharmaceuticals North America, Inc. Zusammensetzung und Verfahren zur verbesserten Abgabe von 5,5-Diphenylbarbitursäure
US20080132529A1 (en) * 2006-11-14 2008-06-05 Avraham Yacobi Method of improving bioavailability for non-sedating barbiturates
EP2755945A1 (de) * 2011-09-12 2014-07-23 Council of Scientific & Industrial Research Arylierte beta-dicarbonylverbindungen und verfahren zu ihrer herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1960170A (en) * 1934-05-22 Cc - phenylethyl - n -
US3930006A (en) * 1963-04-30 1975-12-30 Aspro Nicholas Ltd Antiparkinsonism compositions and method
US4046894A (en) * 1968-08-05 1977-09-06 Bristol-Myers Company Certain barbituric acid derivatives used as anticonvulsant agents
US3919427A (en) * 1972-06-02 1975-11-11 Kendall & Co Therapeutic compositions containing 1-methyl-3-alkoxymethyl-5,5-disubstituted barbituric acid compounds
US3948896A (en) * 1973-02-28 1976-04-06 The Kendall Company N-mono(alkoxymethyl) phenobarbitals, process therefor and therapeutic composition and method containing same

Also Published As

Publication number Publication date
ATE70056T1 (de) 1991-12-15
DK167615B1 (da) 1993-11-29
IE58038B1 (en) 1993-06-16
DK431784D0 (da) 1984-09-11
IE842332L (en) 1985-03-14
EP0137343A3 (en) 1986-06-11
IL69722A0 (en) 1983-12-30
AU571265B2 (en) 1988-04-14
DE3485318D1 (de) 1992-01-16
EP0137343B1 (de) 1991-12-04
JPS6084272A (ja) 1985-05-13
DK431784A (da) 1985-03-15
US4628056A (en) 1986-12-09
EP0137343A2 (de) 1985-04-17
AU3287584A (en) 1985-03-21
JPH0730044B2 (ja) 1995-04-05
ZA847274B (en) 1986-04-30

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired