ATE69837T1 - Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse. - Google Patents

Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse.

Info

Publication number
ATE69837T1
ATE69837T1 AT85304439T AT85304439T ATE69837T1 AT E69837 T1 ATE69837 T1 AT E69837T1 AT 85304439 T AT85304439 T AT 85304439T AT 85304439 T AT85304439 T AT 85304439T AT E69837 T1 ATE69837 T1 AT E69837T1
Authority
AT
Austria
Prior art keywords
measuring
methods
fluorescence
introducing
cell viability
Prior art date
Application number
AT85304439T
Other languages
English (en)
Inventor
M Boris Rotman
Original Assignee
Univ Brown Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brown Res Found filed Critical Univ Brown Res Found
Application granted granted Critical
Publication of ATE69837T1 publication Critical patent/ATE69837T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT85304439T 1984-06-21 1985-06-21 Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse. ATE69837T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/623,183 US4734372A (en) 1983-02-04 1984-06-21 Cell culturing methods and apparatus
EP85304439A EP0171896B1 (de) 1984-06-21 1985-06-21 Methoden und Vorrichtung zur Zellentwicklungsfähigkeitsanalyse

Publications (1)

Publication Number Publication Date
ATE69837T1 true ATE69837T1 (de) 1991-12-15

Family

ID=24497094

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85304439T ATE69837T1 (de) 1984-06-21 1985-06-21 Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse.

Country Status (5)

Country Link
US (1) US4734372A (de)
EP (1) EP0171896B1 (de)
JP (1) JPS6170972A (de)
AT (1) ATE69837T1 (de)
DE (1) DE3584744D1 (de)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937187A (en) * 1983-02-04 1990-06-26 Brown University Research Foundation Methods for separating malignant cells from clinical specimens
US4816395A (en) * 1985-12-19 1989-03-28 Peralta Cancer Research Institute Method for predicting chemosensitivity of anti-cancer drugs
JPS63158459A (ja) * 1986-09-05 1988-07-01 ライフトレイク 感受性アツセイの精度を調整する方法
AU8123787A (en) * 1986-11-17 1988-05-19 Oncotech Method to monitor and circumvent acquired resistance to chemotherapy in humans
US4835102A (en) * 1987-03-31 1989-05-30 Eugene Bell Tissue equivalent test systems
JPH0782009B2 (ja) * 1988-03-24 1995-09-06 工業技術院長 細胞融合方法及び装置
JPH0246298A (ja) * 1988-06-23 1990-02-15 Atomic Energy Canada Ltd 潜在的毒性の試剤に対する有機体の感性の決定法
US5068195A (en) * 1988-11-02 1991-11-26 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion and maintenance vessel
US5139946A (en) * 1988-11-02 1992-08-18 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion
FI83668C (fi) * 1989-09-08 1991-08-12 Johan Eric Walter Ahlqvist Foerfarande och medel foer behandling av cytologiska preparat.
IL95429A (en) * 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
SE464763B (sv) * 1989-10-05 1991-06-10 Gunnar Engstroem Metod och anordning foer att studera cellers/cellaggregats reaktionsmoenster vid perfusion med ett testmedium
CA2027694C (en) * 1989-10-20 2002-03-05 Tadashi Matsunaga Process and apparatus for detecting sensitized leukocyte or antigen
US5104804A (en) * 1990-06-04 1992-04-14 Molecular Devices Corporation Cell assay device used in a microphysiometer
US5240856A (en) * 1991-10-23 1993-08-31 Cellpro Incorporated Apparatus for cell separation
US5672481A (en) * 1991-10-23 1997-09-30 Cellpro, Incorporated Apparatus and method for particle separation in a closed field
US5612188A (en) * 1991-11-25 1997-03-18 Cornell Research Foundation, Inc. Automated, multicompartmental cell culture system
IL106662A (en) * 1993-08-11 1996-10-31 Yissum Res Dev Co Install a flow cell to monitor blood or any single cell suspension under flow
US5686301A (en) * 1993-09-02 1997-11-11 Heraeus Instruments Gmbh Culture vessel for cell cultures
US5599688A (en) * 1993-10-18 1997-02-04 Precision Instrument Design Device and method for circulating fluid over a membrane
US6054287A (en) * 1994-05-27 2000-04-25 Methodist Hospital Of Indiana, Inc. Cell-type-specific methods and devices for the low temperature preservation of the cells of an animal species
US5595866A (en) * 1994-05-27 1997-01-21 Methodist Hospital Of Indiana, Inc. Step-wise method to remove cryoprotectant from sperm
US5565353A (en) * 1994-06-22 1996-10-15 Board Of Regents, The University Of Texas System Perfusable culture device
US6214617B1 (en) 1995-03-28 2001-04-10 Kinetic Biosystems, Inc. Centrifugal fermentation process
US6133019A (en) * 1995-03-28 2000-10-17 Kinetic Biosystems, Inc. Centrifugal fermentation process
US20050266548A1 (en) * 1995-03-28 2005-12-01 Kbi Biopharma, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation with improved rotor
US6916652B2 (en) * 1995-03-28 2005-07-12 Kinetic Biosystems, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation
US5622819A (en) * 1995-03-28 1997-04-22 Kinetic Biosystems, Inc. Centrifugal fermentation process
US6660509B1 (en) 1995-03-28 2003-12-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
US5721135A (en) * 1995-07-06 1998-02-24 Novo Nordisk A/S Apparatus for identifying biologically active substances by their effect on living cells
WO1997017426A1 (en) * 1995-11-08 1997-05-15 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control
US5641893A (en) * 1996-02-22 1997-06-24 University Of Kentucky Research Foundation Chromatographic separation apparatus
NL1007489C2 (nl) * 1996-11-08 2000-10-24 Konink Grolsch N V Werkwijze en inrichting voor het in een medium aantonen van micro-organismen.
DE19721477A1 (de) * 1997-05-23 1998-11-26 Abb Patent Gmbh Mikrobieller Membranreaktor zur Verwendung in Fließsystemen
WO1999047922A2 (en) * 1998-03-18 1999-09-23 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
US6673008B1 (en) 1998-04-28 2004-01-06 Ronald J. Thompson Fallopian tube and method of in vitro fertilization and embryo development
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US6146883A (en) * 1998-09-14 2000-11-14 Navicyte, Inc. Packing device for transporting confluent cell monolayers
DE19932439C2 (de) * 1999-07-12 2002-06-13 Sefar Ag Rueschlikon Bioreaktor
US6642046B1 (en) * 1999-12-09 2003-11-04 Motorola, Inc. Method and apparatus for performing biological reactions on a substrate surface
US6703217B2 (en) 2000-01-31 2004-03-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
AUPQ653000A0 (en) 2000-03-28 2000-04-20 Cook Incorporated Perfusion incubator
AU2001249559B2 (en) * 2000-03-28 2004-10-07 Cook Incorporated Perfusion incubator
US6670170B1 (en) 2000-05-15 2003-12-30 The United States Of America As Represented By The Secretary Of The Army Temperature-regulated cell perifusion chamber
JP5433840B2 (ja) * 2000-09-09 2014-03-05 ザ・リサーチ・ファウンデーション・フォー・ザ・ステイト・ユニヴァーシティ・オブ・ニューヨーク 転移癌細胞を単離するための方法および組成物、ならびに癌の転移能の測定におけるその使用
US20030036049A1 (en) * 2001-01-03 2003-02-20 Medis El Ltd. Optical method for testing sensitivity of cells
TW581119U (en) * 2001-12-19 2004-03-21 Univ Nat Cheng Kung Petri dish for microscope
AU2003228711C1 (en) * 2002-04-26 2010-01-07 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
AU2003228950A1 (en) * 2002-05-08 2003-11-11 Scion Pharmaceuticals, Inc. Oocyte recording chamber
US6980293B1 (en) * 2002-06-11 2005-12-27 Olympus Optical Co., Ltd. Immersion medium supply apparatus, fluorescence spectrometry inspection apparatus, and culture microscope
JP2005533502A (ja) * 2002-07-24 2005-11-10 ボード オブ レジェンツ,ザ ユニバーシティー オブ テキサス システム 膜法による微生物の捕捉と検出
AU2003278564A1 (en) * 2002-10-23 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro test for studying compound predicting pharmacologic and/or pharmacokinetic and/or pharmacodynamic parameters of a compound
US7245368B2 (en) * 2003-03-31 2007-07-17 C & L Instruments Sample chamber for microscopy
WO2004104922A2 (en) 2003-05-16 2004-12-02 Board Of Regents, The University Of Texas System Image and part recognition technology
US9317922B2 (en) 2003-05-16 2016-04-19 Board Of Regents The University Of Texas System Image and part recognition technology
AU2004300168A1 (en) * 2003-12-11 2005-06-30 Board Of Regents, The University Of Texas System Method and system for the analysis of saliva using a sensor array
US20070037276A1 (en) * 2004-02-23 2007-02-15 Eudes Francois Marie De Crecy Continuous culture apparatus with mobile vessel, allowing selection of fitter cell variants and producing a culture in a continuous manner
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
CN1942575B (zh) * 2004-04-13 2012-07-18 东洋制罐株式会社 双层培养容器以及培养方法
US8318479B2 (en) * 2004-05-19 2012-11-27 Massachusetts Institute Of Technology Perfused three-dimensional cell/tissue disease models
JP2006025789A (ja) * 2004-06-17 2006-02-02 Olympus Corp 生体試料観察システムおよび生体試料の観察方法
US20060095021A1 (en) * 2004-11-02 2006-05-04 Casas-Bejar Jesus W Introduction of agent with medical device
EP1910824A4 (de) 2005-05-31 2012-11-21 Labnow Inc Verfahren und zusammensetzungen in zusammenhang mit der erstellung und verwendung eines weissen blutbildes
AU2006259935B2 (en) * 2005-06-23 2011-06-23 Gambro Lundia Ab Implantable access device and method for preparing thereof
AU2006261953B2 (en) * 2005-06-24 2012-02-23 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US20090215646A1 (en) * 2005-07-01 2009-08-27 The Board Of Regents Of The University Of Texas Sy System and method of analyte detection using differential receptors
DE102005051406A1 (de) * 2005-10-27 2007-05-03 Forschungszentrum Rossendorf E.V. Optisches Koppelelement für eine Durchflusszelle
FR2897783B1 (fr) * 2006-02-24 2008-05-30 Millipore Corp Dispositif pour le controle microbiologique, ensembles de controle et d'incubation le comportant et procede le mettant en oeuvre
FR2901806B1 (fr) * 2006-06-01 2008-08-01 Millipore Corp Dispositif et ensemble de controle microbiologique
US20100151571A1 (en) * 2006-07-07 2010-06-17 Georgia Tech Research Corporation Centimeter-scale, integrated diagnostics incubator for biological culturing
WO2008131039A2 (en) * 2007-04-16 2008-10-30 Board Of Regents, The University Of Texas System Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
CA3198597A1 (en) 2008-07-16 2010-01-21 Donald E. Ingber Organ mimic device with microchannels and methods of use and manufacturing thereof
EP2158967A1 (de) * 2008-08-26 2010-03-03 F. Hoffmann-La Roche AG Probenträger
WO2010080643A1 (en) * 2008-12-18 2010-07-15 Biovigilant Systems, Inc. Integrated microbial collector
WO2010127182A1 (en) * 2009-04-29 2010-11-04 Evolugate, Llc Adapting microorganisms for agricultural products
US9574166B2 (en) 2010-08-18 2017-02-21 Drugmode Aps Bioreactor system
EP2652120B1 (de) 2010-12-15 2020-02-26 Drugmode APS Bioreaktor mit deckel für leichten zugang zu einem inkubationsraum
WO2012118799A2 (en) 2011-02-28 2012-09-07 President And Fellows Of Harvard College Cell culture system
US9725687B2 (en) 2011-12-09 2017-08-08 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
JP5989483B2 (ja) * 2012-09-24 2016-09-07 テルモ株式会社 膜状組織の保存輸送容器および保存輸送方法
US9855554B2 (en) 2013-07-22 2018-01-02 President And Fellows Of Harvard College Microfluidic cartridge assembly
GB2538012A (en) 2013-12-20 2016-11-02 Harvard College Low shear microfluidic devices and methods of use and manufacturing thereof
EP3169626A4 (de) 2014-07-14 2018-04-04 President and Fellows of Harvard College Systeme und verfahren zur verbesserten leistung fluidischer und mikrofluidischer systeme
WO2017019542A1 (en) 2015-07-24 2017-02-02 President And Fellows Of Harvard College Radial microfluidic devices and methods of use
CA3000718A1 (en) * 2015-10-02 2017-04-06 Wake Forest University Health Sciences Methods and apparatus for modeling cancer metastasis in vitro
GB2570593B (en) 2016-09-13 2022-10-12 Harvard College Methods relating to intestinal organ-on-a-chip
KR20200116944A (ko) 2018-02-02 2020-10-13 웨이크 포리스트 유니버시티 헬스 사이언시즈 면역요법 관련 오가노이드 및 그의 제조 및 사용 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2942520A (en) * 1955-12-20 1960-06-28 George G Rose Tissue culture device
US3065148A (en) * 1959-07-14 1962-11-20 Technicon Instr Method and apparatus for use in conducting studies on cells
US3691017A (en) * 1970-05-06 1972-09-12 Worthington Bio Chem Corp Means and method for chemical analysis
US3726597A (en) * 1972-03-09 1973-04-10 Us Health Education & Welfare Controlled environment culture system for light microscopy
US3883393A (en) * 1972-05-18 1975-05-13 Us Health Education & Welfare Cell culture on semi-permeable tubular membranes
US3821087A (en) * 1972-05-18 1974-06-28 Dedrick R Cell culture on semi-permeable tubular membranes
DE2319204B2 (de) * 1973-04-16 1977-04-07 CA. Greiner und Söhne, 7440 Nürtingen Arbeitsgeraet fuer histologische untersuchungen
US3928142A (en) * 1973-07-24 1975-12-23 Dennis B Smith Culture chamber for the study of biological systems and method of fabrication thereof
US4201845A (en) * 1976-04-12 1980-05-06 Monsanto Company Cell culture reactor
US4184922A (en) * 1977-11-11 1980-01-22 The Government Of The United States Dual circuit, woven artificial capillary bundle for cell culture
US4220725A (en) * 1978-04-03 1980-09-02 United States Of America Capillary cell culture device
US4242459A (en) * 1978-11-02 1980-12-30 Chick William L Cell culture device
US4241187A (en) * 1979-03-27 1980-12-23 United States Of America Method and apparatus for cell and tissue culture
JPS5642584A (en) * 1979-09-18 1981-04-20 Asahi Chem Ind Co Ltd Cell cultivation method
SU901266A1 (ru) * 1979-12-20 1982-01-30 Предприятие П/Я А-1631 Камера дл культивировани микроорганизмов
US4308351A (en) * 1980-04-18 1981-12-29 Joseph Leighton System for growing tissue cultures
US4440853A (en) * 1980-08-21 1984-04-03 Board Of Trustees Of The Leland Stanford Junior University Microbiological methods using hollow fiber membrane reactor
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices

Also Published As

Publication number Publication date
EP0171896B1 (de) 1991-11-27
EP0171896A1 (de) 1986-02-19
JPH0574358B2 (de) 1993-10-18
DE3584744D1 (de) 1992-01-09
JPS6170972A (ja) 1986-04-11
US4734372A (en) 1988-03-29

Similar Documents

Publication Publication Date Title
ATE69837T1 (de) Methoden und vorrichtung zur zellentwicklungsfaehigkeitsanalyse.
Soll et al. Zoospore germination in the water mold, Blastocladiella emersonii: I. Measurement of germination and sequence of subcellular morphological changes
ATE449837T1 (de) Abstammungs-spezifische zellen und vorläuferzellen
ATE79522T1 (de) Vorrichtung zum sammeln und/oder zuechten geschuetzter biologischer zuechtungen.
Lu et al. A microdevice platform for visualizing mitochondrial transport in aligned dopaminergic axons
ATE73843T1 (de) Trennverfahren fuer motile saatzellen in vitro, befruchtungsverfahren und durchdringungsmedium fuer saatzellen.
FR2397634A1 (fr) Procede et dispositif d'analyse de la fluorescence de particules colorees, en particulier de cellules biologiques
DK161011C (da) Praeparat til kontinuerlig frigivelse af naeringsstoffer og/eller terapeutiske stoffer til droevtyggere samt fremgangsmaade til fremstilling heraf
BR8707673A (pt) Processo para reproduzir medula ossea
CN104593253A (zh) 一种快速检测微生物耐药性的方法及专用微流控芯片
DE59709562D1 (de) Verfahren und Vorrichtung zur Kontolle der Tablettenparameter
Emanuelsson et al. Inhibition of putrescine synthesis blocks development of the polychete Ophryotrocha labronica at gastrulation.
GB2036307B (en) Method for the determination of biological substances by diffusion in a porous matrix or by electrophoriesis
DK1466967T3 (da) Apparat til fremstilling af ordnede sæt af vævspröver
ATE85357T1 (de) Verfahren und vorrichtung zum kultivieren von zellen.
GB9927801D0 (en) Method
ES2070996T3 (es) Un metodo y aparato para insertar material en celulas biologicas.
IT1205100B (it) Dispositivo per culture microbiologiche
FR2491928B1 (fr) Cristaux de b-nicotinamide adenine dinucleotide et procede de leur preparation
CA1170555A (en) Method of diagnosis and an outfit for carrying it out
JPS5423119A (en) Erythrocyte for haemagglutination test
DE3382468D1 (de) Verfahren zur zellkultur in vitro.
ATE47425T1 (de) Verfahren und vorrichtung fuer die -i(in-vitro)kultur von pflanzen-zellen und -organen sowie fuer die mikropropagation und die regeneration von ganzen pflanzen.
DiGiovanni et al. First Information About N, P Nutrients and the Production of Lake Trasimeno,(In Italian)
TUPYK et al. BIOCHEMICAL CHARACTERISTICS OF SPIRULINA PLATENSIS(GOM.) GEITL.: I. WATER-SOLUBLE GROUP B VITAMINS,(IN UKRANIAN)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties