ATE69813T1 - Als antiemetika oder antipsychotika nuetzliche carboxamide. - Google Patents

Als antiemetika oder antipsychotika nuetzliche carboxamide.

Info

Publication number
ATE69813T1
ATE69813T1 AT87301447T AT87301447T ATE69813T1 AT E69813 T1 ATE69813 T1 AT E69813T1 AT 87301447 T AT87301447 T AT 87301447T AT 87301447 T AT87301447 T AT 87301447T AT E69813 T1 ATE69813 T1 AT E69813T1
Authority
AT
Austria
Prior art keywords
group
antiemetics
antipsychotics
carboxamides useful
carboxamides
Prior art date
Application number
AT87301447T
Other languages
English (en)
Inventor
Daniel Lednicer
Jung-Hui Sun
Original Assignee
Adria Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adria Lab Inc filed Critical Adria Lab Inc
Application granted granted Critical
Publication of ATE69813T1 publication Critical patent/ATE69813T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT87301447T 1986-02-28 1987-02-19 Als antiemetika oder antipsychotika nuetzliche carboxamide. ATE69813T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83500686A 1986-02-28 1986-02-28
US06/868,899 US4888353A (en) 1986-02-28 1986-05-23 Carboxamides useful as antiemetic or antipsychotic agents
EP87301447A EP0234872B1 (de) 1986-02-28 1987-02-19 Als Antiemetika oder Antipsychotika nützliche Carboxamide

Publications (1)

Publication Number Publication Date
ATE69813T1 true ATE69813T1 (de) 1991-12-15

Family

ID=27125749

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87301447T ATE69813T1 (de) 1986-02-28 1987-02-19 Als antiemetika oder antipsychotika nuetzliche carboxamide.

Country Status (5)

Country Link
US (1) US4888353A (de)
EP (1) EP0234872B1 (de)
AT (1) ATE69813T1 (de)
CA (1) CA1301170C (de)
DE (1) DE3774727D1 (de)

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US5122361A (en) * 1989-04-17 1992-06-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and imaging agents
US5186921A (en) * 1989-04-17 1993-02-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and image agents
US5185333A (en) * 1989-07-03 1993-02-09 Yoshitomi Pharmaceutical Industries, Ltd. Benzazine compounds and pharmaceutical uses thereof
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US5114947A (en) * 1990-12-27 1992-05-19 Erbamont Inc. Method for alleviating anxiety using benzobicyclic carboxamides
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US5177244A (en) * 1991-03-07 1993-01-05 Eli Lilly And Company Process and intermediates to 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxylic acids
US5142069A (en) * 1991-03-07 1992-08-25 Eli Lilly And Company Process of preparing 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxylic acids
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CA2129112A1 (en) * 1992-02-06 1993-08-19 Francis David King Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists
US5446147A (en) * 1992-04-03 1995-08-29 Trustees Of The University Of Pennsylvania Fluorinated and iodinated dopamine agents
MX9306311A (es) * 1992-10-13 1994-04-29 Smithkline Beecham Plc Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen
US6127379A (en) * 1993-02-01 2000-10-03 Smithkline Beecham P.L.C. Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
US5911970A (en) * 1993-05-06 1999-06-15 Research Corporation Technologies, Inc. Methods for cancer imaging and therapy using benzamine compounds
US6517811B2 (en) 1993-05-06 2003-02-11 Research Corporation Technologies, Inc. Compounds for cancer imaging and therapy
JPH08510235A (ja) * 1993-05-06 1996-10-29 ジョン、クリスティー・エス 癌の撮像及び治療用化合物
US5993777A (en) * 1993-05-06 1999-11-30 Research Corporation Technologies, Inc. Benzamide compounds for cancer imaging and therapy
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
FR2735475B1 (fr) * 1995-06-13 1997-07-11 Synthelabo Derives de n-((1,4-diazabicyclo(2.2.2)oct-2-yl)methyl) benzamide, leur preparation et leur application en therapeutique
US5703235A (en) * 1996-03-21 1997-12-30 Neurogen Corporation N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor subtype specific ligands
AR036041A1 (es) * 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
EP1425286B1 (de) * 2001-09-12 2007-02-28 Pharmacia & Upjohn Company LLC Substituierte 7-aza-[2.2.1]bicycloheptane für die behandlung von krankheiten
DK1432707T3 (da) 2001-10-02 2012-06-11 Pharmacia & Upjohn Co Llc Azabicyklisk-substituerede kondenserede heteroarylforbindelser til behandling af sygdomme
WO2003070732A1 (en) * 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease
WO2003070731A2 (en) * 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Azabicyclic compounds for the treatment of disease
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US20100260669A1 (en) * 2004-05-13 2010-10-14 Anthony Joonkyoo Yun Treatment of Seasonal Conditions Through Modulation of the Autonomic Nervous System
AR074760A1 (es) 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
JP5746334B2 (ja) 2010-06-16 2015-07-08 シマベイ セラピューティクス， インコーポレーテッド Ｇｐｒ１２０受容体作動薬及びその使用
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
MX348548B (es) 2011-08-18 2017-06-19 Nippon Shinyaku Co Ltd Derivado heterociclico y farmaceutico.

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MC807A1 (fr) * 1968-07-29 1970-07-30 Soc Et Scient Et Ind De L Ile Procédé de préparation de 3-alcoxy-thianaphtene-carboxamide substituées ou non
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AU1804476A (en) * 1975-09-24 1978-04-06 Riker Laboratories Inc Phenylbenzofurans
FR2396757A2 (fr) * 1977-07-08 1979-02-02 Ile De France Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation
US4205080A (en) * 1977-07-21 1980-05-27 Shell Oil Company 2,3-Dihydro benzofuran carboxamides
US4207327A (en) * 1977-08-19 1980-06-10 A. H. Robins Company, Inc. N-(4-Pyrazolidinyl)benzamides and their amino precursors
EP0068700A1 (de) * 1981-06-29 1983-01-05 Beecham Group Plc Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
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FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
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Also Published As

Publication number Publication date
CA1301170C (en) 1992-05-19
US4888353A (en) 1989-12-19
EP0234872A1 (de) 1987-09-02
EP0234872B1 (de) 1991-11-27
DE3774727D1 (de) 1992-01-09

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee