ATE66492T1 - Aktivierte 'aryl-beendete' fluoreszierende verbindungen und testverfahren und systeme in denen dieselben als fluorogenische ausgangsmaterialien verwendet werden. - Google Patents
Aktivierte 'aryl-beendete' fluoreszierende verbindungen und testverfahren und systeme in denen dieselben als fluorogenische ausgangsmaterialien verwendet werden.Info
- Publication number
- ATE66492T1 ATE66492T1 AT83307183T AT83307183T ATE66492T1 AT E66492 T1 ATE66492 T1 AT E66492T1 AT 83307183 T AT83307183 T AT 83307183T AT 83307183 T AT83307183 T AT 83307183T AT E66492 T1 ATE66492 T1 AT E66492T1
- Authority
- AT
- Austria
- Prior art keywords
- aryl
- peroxidase
- fluorescent
- annular carbon
- carbon atom
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000003556 assay Methods 0.000 title abstract 2
- 239000007858 starting material Substances 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 7
- 102000003992 Peroxidases Human genes 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 108040007629 peroxidase activity proteins Proteins 0.000 abstract 4
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 239000007850 fluorescent dye Substances 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000002837 carbocyclic group Chemical group 0.000 abstract 2
- 125000005647 linker group Chemical group 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- -1 diaryl organic compound Chemical class 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Chemical group 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/444,658 US4857455A (en) | 1982-11-26 | 1982-11-26 | Method for the determination of peroxidase using fluorogenic substrates |
| EP83307183A EP0110682B1 (de) | 1982-11-26 | 1983-11-24 | Aktivierte 'aryl-beendete' fluoreszierende Verbindungen und Testverfahren und Systeme in denen dieselben als fluorogenische Ausgangsmaterialien verwendet werden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE66492T1 true ATE66492T1 (de) | 1991-09-15 |
Family
ID=23765817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83307183T ATE66492T1 (de) | 1982-11-26 | 1983-11-24 | Aktivierte 'aryl-beendete' fluoreszierende verbindungen und testverfahren und systeme in denen dieselben als fluorogenische ausgangsmaterialien verwendet werden. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4857455A (de) |
| EP (1) | EP0110682B1 (de) |
| JP (1) | JPH0655158B2 (de) |
| AT (1) | ATE66492T1 (de) |
| CA (1) | CA1338608C (de) |
| DE (1) | DE3382380D1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4670379A (en) * | 1984-12-19 | 1987-06-02 | E. I. Du Pont De Nemours And Company | Polynucleotide hydridization assays employing catalyzed luminescence |
| DE3619436A1 (de) * | 1986-06-10 | 1987-12-17 | Bayer Ag | Triaryl- und trihetarylmethanderivate als redoxindikatoren und deren verwendung |
| US5290682A (en) * | 1991-05-31 | 1994-03-01 | Polaroid Corporation | Enzyme controlled processes and products |
| ATE147400T1 (de) * | 1991-08-13 | 1997-01-15 | Bayer Ag | Fluoreszierendes etikett |
| US5587472A (en) * | 1991-08-13 | 1996-12-24 | Bayer Corporation | Coumarin-labeled nucleoside 5'-triphosphates |
| US5851785A (en) * | 1992-02-04 | 1998-12-22 | Kyowa Medex Co., Ltd. | Method of quantitative determination of substances using coumarin derivatives |
| US5557522A (en) * | 1993-09-10 | 1996-09-17 | Nissan Motor Co., Ltd. | Apparatus and method for guiding vehicle occupant to travel from present position of vehicle to set destination through display unit |
| US6143492A (en) * | 1998-12-14 | 2000-11-07 | Aurora Biosciences Corporation | Optical molecular sensors for cytochrome P450 activity |
| US6420130B1 (en) | 1998-12-14 | 2002-07-16 | Aurora Biosciences Corporation | Optical molecular sensors for cytochrome P450 activity |
| US6514687B1 (en) | 1998-12-14 | 2003-02-04 | Vertex Pharmaceuticals (San Diego), Llc | Optical molecular sensors for cytochrome P450 activity |
| EP1140888B1 (de) * | 1998-12-14 | 2003-05-14 | Vertex Pharmaceuticals (San Diego) LLC | Optische molekularsensoren für cytochrome p-450 aktivität |
| US6329165B1 (en) * | 1999-12-30 | 2001-12-11 | Nalco Chemical Company | Measurement and control of sessile and planktonic microbiological activity in industrial water systems |
| US11237170B2 (en) | 2018-12-04 | 2022-02-01 | Aat Bioquest, Inc. | Styryl phenols, derivatives and their use in methods of analyte detection |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3553235A (en) * | 1968-09-30 | 1971-01-05 | Us Agriculture | 7-acyloxy-4-methyl-coumarins |
| US4279992A (en) * | 1978-03-13 | 1981-07-21 | Miles Laboratories, Inc. | Specific binding assay employing an enzyme-cleavable substrate as label |
| US4269938A (en) * | 1979-03-08 | 1981-05-26 | Eastman Kodak Company | Assay of peroxidatively active materials |
| US4307188A (en) * | 1979-09-06 | 1981-12-22 | Miles Laboratories, Inc. | Precursor indicator compositions |
| US4318846A (en) * | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US4367238A (en) * | 1980-01-28 | 1983-01-04 | Fujisawa Pharmaceutical Company, Ltd. | Phenyl-alkanoic acid derivative and preparation thereof |
| US4273715A (en) * | 1980-04-14 | 1981-06-16 | Miles Laboratories, Inc. | N-(hydroxyalkyl)-7-hydroxycoumarin-3-carboxamides |
| US4318981A (en) * | 1980-04-24 | 1982-03-09 | Miles Laboratories, Inc. | Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label |
| US4439356A (en) * | 1981-03-03 | 1984-03-27 | Syva Company | Unsymmetrical fluorescein derivatives |
| JPS57150399A (en) * | 1981-03-13 | 1982-09-17 | Fuji Photo Film Co Ltd | Reagent for determining hydrogen peroxide and its determination method |
-
1982
- 1982-11-26 US US06/444,658 patent/US4857455A/en not_active Expired - Fee Related
-
1983
- 1983-11-24 AT AT83307183T patent/ATE66492T1/de active
- 1983-11-24 CA CA000441882A patent/CA1338608C/en not_active Expired - Fee Related
- 1983-11-24 EP EP83307183A patent/EP0110682B1/de not_active Expired - Lifetime
- 1983-11-24 JP JP58219666A patent/JPH0655158B2/ja not_active Expired - Lifetime
- 1983-11-24 DE DE8383307183T patent/DE3382380D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0110682A3 (en) | 1986-04-16 |
| JPH0655158B2 (ja) | 1994-07-27 |
| CA1338608C (en) | 1996-09-24 |
| EP0110682B1 (de) | 1991-08-21 |
| EP0110682A2 (de) | 1984-06-13 |
| DE3382380D1 (de) | 1991-09-26 |
| JPS59106300A (ja) | 1984-06-19 |
| US4857455A (en) | 1989-08-15 |
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