ATE66474T1 - Verfahren zur herstellung von substituierten 3chinolincarbonsaeuren. - Google Patents

Verfahren zur herstellung von substituierten 3chinolincarbonsaeuren.

Info

Publication number
ATE66474T1
ATE66474T1 AT86302687T AT86302687T ATE66474T1 AT E66474 T1 ATE66474 T1 AT E66474T1 AT 86302687 T AT86302687 T AT 86302687T AT 86302687 T AT86302687 T AT 86302687T AT E66474 T1 ATE66474 T1 AT E66474T1
Authority
AT
Austria
Prior art keywords
preparation
acids
substituted
sub
ester
Prior art date
Application number
AT86302687T
Other languages
English (en)
Inventor
John M Domagala
Mel C Schroeder
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE66474T1 publication Critical patent/ATE66474T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
AT86302687T 1985-04-15 1986-04-11 Verfahren zur herstellung von substituierten 3chinolincarbonsaeuren. ATE66474T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/723,019 US4578473A (en) 1985-04-15 1985-04-15 Process for quinoline-3-carboxylic acid antibacterial agents
EP86302687A EP0198678B1 (de) 1985-04-15 1986-04-11 Verfahren zur Herstellung von substituierten 3-Chinolincarbonsäuren

Publications (1)

Publication Number Publication Date
ATE66474T1 true ATE66474T1 (de) 1991-09-15

Family

ID=24904467

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86302687T ATE66474T1 (de) 1985-04-15 1986-04-11 Verfahren zur herstellung von substituierten 3chinolincarbonsaeuren.

Country Status (22)

Country Link
US (1) US4578473A (de)
EP (1) EP0198678B1 (de)
JP (1) JPS61238779A (de)
KR (1) KR860008163A (de)
CN (1) CN86102449A (de)
AT (1) ATE66474T1 (de)
AU (2) AU589415B2 (de)
CA (1) CA1277661C (de)
DD (1) DD244135A5 (de)
DE (1) DE3680938D1 (de)
DK (1) DK166186A (de)
ES (1) ES8800667A1 (de)
FI (1) FI861547A (de)
GR (1) GR860966B (de)
HU (1) HU195497B (de)
IL (1) IL78275A (de)
NO (1) NO168475C (de)
NZ (1) NZ215808A (de)
OA (1) OA08277A (de)
PH (1) PH22731A (de)
PT (1) PT82381B (de)
ZA (1) ZA862384B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4771054A (en) * 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
JPH0635457B2 (ja) * 1985-06-28 1994-05-11 杏林製薬株式会社 ピリドンカルボン酸誘導体およびその製造方法
IN166416B (de) * 1985-09-18 1990-05-05 Pfizer
JPH0637489B2 (ja) * 1985-09-21 1994-05-18 杏林製薬株式会社 キノロンカルボン酸誘導体およびその製造方法
US4840956A (en) * 1986-02-18 1989-06-20 Warner-Lambert Company Novel disubstituted-7-pyrrolidinoquinoline antibacterial agents
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
US4826985A (en) * 1986-04-25 1989-05-02 Abbott Laboratories Intermediates for preparation of racemate and optically active ofloxacin and related derivatives
FI88506C (fi) * 1986-07-04 1993-05-25 Chemie Linz Gmbh Foerfarande foer framstaellning av farmaceutiskt anvaendbar 7-diazabicykloalkyl-6-fluor-1-(2,4-difluorfenyl)-1,4-dihydro-4-oxo-kinolin-3-karboxylsyra eller karboxylsyraester
ZA877471B (en) * 1986-10-08 1988-04-05 Bristol-Myers Company 1-tertiary-alkyl-substituted naphthyridine-and quinoline-carboxylic acid antibacterial agents
NZ222047A (en) * 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
WO1989000158A1 (en) * 1987-07-02 1989-01-12 Pfizer Inc. Bridged-diazabicycloalkyl quinolone carboxylic acids and esters
US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5103040A (en) * 1988-06-21 1992-04-07 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5104868A (en) * 1988-06-21 1992-04-14 Pfizer Inc. Tricyclic derivatives of 7-substituted-6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acids and esters
US5233091A (en) * 1988-06-21 1993-08-03 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
US11585397B2 (en) 2020-11-30 2023-02-21 Honeywell International Inc. Piston cap

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2069482B (en) * 1980-02-14 1984-04-04 Gist Brocades Nv Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
US4499091A (en) * 1982-03-31 1985-02-12 Sterling Drug Inc. 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents
US4638067A (en) * 1982-09-09 1987-01-20 Warner-Lambert Co. Antibacterial agents
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
JPS60123837A (ja) * 1983-12-09 1985-07-02 Mitsubishi Paper Mills Ltd ハロゲン化銀写真乳剤

Also Published As

Publication number Publication date
AU6687086A (en) 1987-10-08
IL78275A (en) 1989-09-10
ES8800667A1 (es) 1987-11-16
CN86102449A (zh) 1986-10-15
AU589415B2 (en) 1989-10-12
KR860008163A (ko) 1986-11-12
NO861449L (no) 1986-10-16
IL78275A0 (en) 1986-07-31
JPS61238779A (ja) 1986-10-24
US4578473A (en) 1986-03-25
PT82381B (pt) 1988-05-27
DK166186D0 (da) 1986-04-11
PH22731A (en) 1988-11-28
HU195497B (en) 1988-05-30
DE3680938D1 (de) 1991-09-26
DK166186A (da) 1986-10-16
ZA862384B (en) 1987-11-25
PT82381A (en) 1986-05-01
NO168475C (no) 1992-02-26
NZ215808A (en) 1988-08-30
CA1277661C (en) 1990-12-11
GR860966B (en) 1986-08-06
ES553991A0 (es) 1987-11-16
HUT41019A (en) 1987-03-30
EP0198678A3 (en) 1987-03-25
AU596820B2 (en) 1990-05-17
AU5567486A (en) 1986-10-23
FI861547A0 (fi) 1986-04-11
EP0198678B1 (de) 1991-08-21
FI861547A (fi) 1986-10-16
OA08277A (en) 1987-10-30
NO168475B (no) 1991-11-18
EP0198678A2 (de) 1986-10-22
DD244135A5 (de) 1987-03-25

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