ATE63126T1 - Tetra- und penta-peptide mit der sequenz lysylarginyl-aspartyl, und ihre verwendung als antithrombotika. - Google Patents

Tetra- und penta-peptide mit der sequenz lysylarginyl-aspartyl, und ihre verwendung als antithrombotika.

Info

Publication number
ATE63126T1
ATE63126T1 AT88402713T AT88402713T ATE63126T1 AT E63126 T1 ATE63126 T1 AT E63126T1 AT 88402713 T AT88402713 T AT 88402713T AT 88402713 T AT88402713 T AT 88402713T AT E63126 T1 ATE63126 T1 AT E63126T1
Authority
AT
Austria
Prior art keywords
configuration
peptides
lysylarginyl
antitrombotics
aspartyl
Prior art date
Application number
AT88402713T
Other languages
English (en)
Inventor
Pierre Jolles
Anne-Marie Fiat
Claudine Soria
Sylviane Levy-Toledano
Sanghamitra Indian Instit Raha
Elizabeth Mazoyer
Ludovic Drouet
Original Assignee
Inst Vaisseaux Et Du Sang
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Vaisseaux Et Du Sang, Centre Nat Rech Scient filed Critical Inst Vaisseaux Et Du Sang
Application granted granted Critical
Publication of ATE63126T1 publication Critical patent/ATE63126T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT88402713T 1987-10-30 1988-10-27 Tetra- und penta-peptide mit der sequenz lysylarginyl-aspartyl, und ihre verwendung als antithrombotika. ATE63126T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8715061A FR2622587B1 (fr) 1987-10-30 1987-10-30 Peptide lysyl-arginyl-aspartyl-serine et ses applications en tant que medicament, notamment antithrombotique
EP88402713A EP0314576B1 (de) 1987-10-30 1988-10-27 Tetra- und Penta-peptide mit der Sequenz Lysyl-Arginyl-Aspartyl, und ihre Verwendung als Antithrombotika

Publications (1)

Publication Number Publication Date
ATE63126T1 true ATE63126T1 (de) 1991-05-15

Family

ID=9356340

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88402713T ATE63126T1 (de) 1987-10-30 1988-10-27 Tetra- und penta-peptide mit der sequenz lysylarginyl-aspartyl, und ihre verwendung als antithrombotika.

Country Status (6)

Country Link
US (1) US4943562A (de)
EP (1) EP0314576B1 (de)
JP (1) JPH01149799A (de)
AT (1) ATE63126T1 (de)
DE (1) DE3862637D1 (de)
FR (1) FR2622587B1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639409B2 (en) * 1987-12-10 1993-07-29 La Jolla Cancer Research Foundation Conformationally stabilized cell adhesion peptides
US5827821A (en) * 1987-12-10 1998-10-27 The Burnham Institute Conformationally stabilized cell adhesion peptides
GB8905606D0 (en) * 1989-03-11 1989-04-26 Scras Peptides
US5795867A (en) * 1989-06-16 1998-08-18 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5686568A (en) * 1989-06-16 1997-11-11 Cor Therapeutics, Inc. Platelet aggregration inhibitors
US5318899A (en) * 1989-06-16 1994-06-07 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5612311A (en) * 1990-04-06 1997-03-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
JPH05509294A (ja) * 1990-04-06 1993-12-22 ラ　ホヤ　キャンサー　リサーチ　ファウンデーション 血栓症治療のための方法および組成物
US5648330A (en) * 1990-04-06 1997-07-15 La Jolla Cancer Research Foundation Method and composition for treating vascular graft occlusion
US6521594B1 (en) 1990-04-06 2003-02-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5672585A (en) * 1990-04-06 1997-09-30 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5780303A (en) * 1990-04-06 1998-07-14 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5492894A (en) * 1991-03-21 1996-02-20 The Procter & Gamble Company Compositions for treating wrinkles comprising a peptide
US5338725A (en) * 1992-06-30 1994-08-16 The Research Foundation Of The State University Of New York Anti-aggregatory agents for platelets
US5705486A (en) * 1996-03-14 1998-01-06 Yoshihide Hagiwara Isolation of novel peptides from green barley leaf extract and use same to inhibit human platelet aggregation
US6210904B1 (en) * 1997-10-14 2001-04-03 Merck & Co., Inc. Anticoagulant test
US7148197B2 (en) * 2000-08-24 2006-12-12 The Regents Of The University Of California Orally administered small peptides synergize statin activity
US8209514B2 (en) * 2008-02-04 2012-06-26 Qnx Software Systems Limited Media processing system having resource partitioning

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190646A (en) * 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
US4190647A (en) * 1979-01-26 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptides and methods
US4298523A (en) * 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4305852A (en) * 1980-10-20 1981-12-15 American Home Products Corporation Polypeptide compositions
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
US4792525A (en) * 1982-08-04 1988-12-20 La Jolla Cancer Research Foundation Tetrapeptide
US4683291A (en) * 1985-10-28 1987-07-28 Scripps Clinic And Research Foundation Platelet binding inhibitors

Also Published As

Publication number Publication date
FR2622587B1 (fr) 1990-12-21
EP0314576B1 (de) 1991-05-02
EP0314576A1 (de) 1989-05-03
FR2622587A1 (fr) 1989-05-05
US4943562A (en) 1990-07-24
JPH01149799A (ja) 1989-06-12
DE3862637D1 (de) 1991-06-06

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Legal Events

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