ATE56212T1 - Verfahren zur herstellung von pyrrolopyridinderivaten und so erhaltene derivate. - Google Patents
Verfahren zur herstellung von pyrrolopyridinderivaten und so erhaltene derivate.Info
- Publication number
- ATE56212T1 ATE56212T1 AT85870178T AT85870178T ATE56212T1 AT E56212 T1 ATE56212 T1 AT E56212T1 AT 85870178 T AT85870178 T AT 85870178T AT 85870178 T AT85870178 T AT 85870178T AT E56212 T1 ATE56212 T1 AT E56212T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- temperature
- electrophilic group
- pyrrolopyride
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- SRSKXJVMVSSSHB-UHFFFAOYSA-N 1h-pyrrolo[3,2-c]pyridine Chemical group N1=CC=C2NC=CC2=C1 SRSKXJVMVSSSHB-UHFFFAOYSA-N 0.000 abstract 2
- KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 abstract 1
- -1 alkyl lithium Chemical compound 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006138 lithiation reaction Methods 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- AFRJJFRNGGLMDW-UHFFFAOYSA-N lithium amide Chemical compound [Li+].[NH2-] AFRJJFRNGGLMDW-UHFFFAOYSA-N 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8419029A FR2574406B1 (fr) | 1984-12-12 | 1984-12-12 | Nouveaux derives de pyrrolo-pyridine, leurs procedes de preparation ainsi que leurs applications |
| EP85870178A EP0187631B1 (de) | 1984-12-12 | 1985-12-11 | Verfahren zur Herstellung von Pyrrolopyridinderivaten und so erhaltene Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE56212T1 true ATE56212T1 (de) | 1990-09-15 |
Family
ID=9310535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85870178T ATE56212T1 (de) | 1984-12-12 | 1985-12-11 | Verfahren zur herstellung von pyrrolopyridinderivaten und so erhaltene derivate. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4831144A (de) |
| EP (1) | EP0187631B1 (de) |
| JP (1) | JPS61155385A (de) |
| AT (1) | ATE56212T1 (de) |
| CA (1) | CA1299183C (de) |
| DE (1) | DE3579577D1 (de) |
| DK (1) | DK576885A (de) |
| FR (1) | FR2574406B1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1756109B1 (de) * | 2004-05-03 | 2016-07-13 | Janssen Pharmaceutica NV | Neue indolderivate als selektive androgen rezeptor modulatoren (sarms) |
| EP2731439A4 (de) * | 2011-07-12 | 2014-12-03 | Merck Sharp & Dohme | Trka-kinase-hemmer, zusammensetzungen daraus und verfahren dafür |
-
1984
- 1984-12-12 FR FR8419029A patent/FR2574406B1/fr not_active Expired
-
1985
- 1985-12-11 EP EP85870178A patent/EP0187631B1/de not_active Expired - Lifetime
- 1985-12-11 DE DE8585870178T patent/DE3579577D1/de not_active Expired - Fee Related
- 1985-12-11 CA CA000497380A patent/CA1299183C/en not_active Expired - Fee Related
- 1985-12-11 AT AT85870178T patent/ATE56212T1/de not_active IP Right Cessation
- 1985-12-12 DK DK576885A patent/DK576885A/da not_active Application Discontinuation
- 1985-12-12 JP JP60280176A patent/JPS61155385A/ja active Pending
-
1988
- 1988-01-07 US US07/141,508 patent/US4831144A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3579577D1 (de) | 1990-10-11 |
| FR2574406A1 (fr) | 1986-06-13 |
| DK576885A (da) | 1986-06-13 |
| EP0187631B1 (de) | 1990-09-05 |
| JPS61155385A (ja) | 1986-07-15 |
| FR2574406B1 (fr) | 1987-02-27 |
| DK576885D0 (da) | 1985-12-12 |
| EP0187631A1 (de) | 1986-07-16 |
| CA1299183C (en) | 1992-04-21 |
| US4831144A (en) | 1989-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |