ATE557082T1 - Sequenz positionen zur anpassung bei prrsv - Google Patents

Sequenz positionen zur anpassung bei prrsv

Info

Publication number
ATE557082T1
ATE557082T1 AT02076334T AT02076334T ATE557082T1 AT E557082 T1 ATE557082 T1 AT E557082T1 AT 02076334 T AT02076334 T AT 02076334T AT 02076334 T AT02076334 T AT 02076334T AT E557082 T1 ATE557082 T1 AT E557082T1
Authority
AT
Austria
Prior art keywords
amino acid
positions
arterivirus
specifically
amino acids
Prior art date
Application number
AT02076334T
Other languages
German (de)
English (en)
Inventor
Rijn Petrus Antonius Van
Johanna Jacoba Maria Meulenberg
Michiel Kroese
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Application granted granted Critical
Publication of ATE557082T1 publication Critical patent/ATE557082T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10061Methods of inactivation or attenuation
    • C12N2770/10064Methods of inactivation or attenuation by serial passage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02076334T 2002-04-05 2002-04-05 Sequenz positionen zur anpassung bei prrsv ATE557082T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02076334A EP1350840B1 (en) 2002-04-05 2002-04-05 Adaptation sites of PRRSV

Publications (1)

Publication Number Publication Date
ATE557082T1 true ATE557082T1 (de) 2012-05-15

Family

ID=27838115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02076334T ATE557082T1 (de) 2002-04-05 2002-04-05 Sequenz positionen zur anpassung bei prrsv

Country Status (5)

Country Link
US (1) US7312030B2 (enExample)
EP (1) EP1350840B1 (enExample)
JP (1) JP4477307B2 (enExample)
AT (1) ATE557082T1 (enExample)
CA (1) CA2424400C (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
PL204373B1 (pl) * 1999-03-08 2010-01-29 Boehringer Ingelheim Vetemendi Replikony zespołu reprodukcyjnego i oddechowego świń (PRRSV), zastosowanie replikonów PRRSV, szczepionki zawierające replikony PRRSV i zastosowanie tych szczepionek
AU4482200A (en) * 1999-04-22 2000-11-10 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
SG153829A1 (en) * 2004-06-18 2009-07-29 Univ Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) * 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
WO2006055331A2 (en) * 2004-11-19 2006-05-26 Intervet International B.V. Porcine reproductive and respiratory syndrome virus strains and compositions
PL2369001T3 (pl) 2005-06-24 2017-06-30 Regents Of The University Of Minnesota Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania
EP1929047B1 (en) * 2005-08-30 2010-03-17 Board of Regents of the University of Nebraska Methods and compositions for vaccination of animals with prrsv antigens with improved immunogenicity
WO2009014919A2 (en) * 2007-07-13 2009-01-29 Iowa State University Research Foundation, Inc. H2n3 influenza a viruses and methods of use
US20110117129A1 (en) * 2008-08-25 2011-05-19 Boehringer Ingelheim Vetmedica, Inc. Vaccine Against Highly Pathogenic Porcine Reproductive and Respiratory Syndrome (HP PRRS)
AR078253A1 (es) * 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
PL2675475T3 (pl) 2011-02-17 2015-12-31 Boehringer Ingelheim Vetmedica Gmbh Nowy europejski szczep prrs
EP2675476B1 (en) 2011-02-17 2015-09-16 Boehringer Ingelheim Vetmedica GmbH Commercial scale process for production of prrsv
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
JP6886291B2 (ja) 2013-12-20 2021-06-16 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH PRRSウイルス変異株、ヨーロッパ型PRRSウイルスcDNAクローンおよびそれらの使用

Also Published As

Publication number Publication date
JP2004121220A (ja) 2004-04-22
US20030219732A1 (en) 2003-11-27
US7312030B2 (en) 2007-12-25
EP1350840B1 (en) 2012-05-09
CA2424400A1 (en) 2003-10-05
JP4477307B2 (ja) 2010-06-09
EP1350840A1 (en) 2003-10-08
CA2424400C (en) 2012-08-21

Similar Documents

Publication Publication Date Title
ATE557082T1 (de) Sequenz positionen zur anpassung bei prrsv
DK1476541T3 (da) Cytokin (zcytor17-ligand)
SG171577A1 (en) Methods for producing yeast-based vaccines
DK1680509T3 (da) Fremgangsmåde til fremstilling af carbonhydrider og oxygenholdige forbindelser fra biomasse der inkluderer fermentation med tilsætning af aminosyre (leu, ile, val)
DE50214630D1 (de) Verfahren zur grosstechnischen herstellung von impfstoffen
DK1082293T3 (da) Formoterol-polymorfer
NO20014364D0 (no) Ny cytokin-zalphall-ligand
ATE501264T1 (de) Enzymatische verfahren zur herstellung 4- substituierter 3-hydroxybuttersäure-derivate
NO20074895L (no) Isoksazolin derivat og ny fremgangsmate for fremstilling derav
DE60042035D1 (de) Verfahren und zusammensetzungen zur herstellung von ophtalmischen linsen
EA200400195A1 (ru) Способ репродукции вируса
BRPI0410861A (pt) métodos e composições para a produção de aminoácidos
ITMI20022076A1 (it) Sali di intermedi del cefdinir.
BR0303570A (pt) Gene de fator de crescimento de hepatócito hìbrido tendo eficiência de expressão elevada de dois heterotipos de fator de crescimento de hepatócito
ATE354648T1 (de) Verfahren zur herstellung eines virus inaktivierten thrombin präparates
EA200801109A1 (ru) Состав для литья и способ его получения
DK1200561T3 (da) Rekombinant stabil celleklon, dens fremstilling og anvendelse
WO2006021559A3 (de) Verfahren zur herstellung von tiotropiumsalzen und silicium-derivate als zwischenprodukte
DK1127886T3 (da) Syntese af 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2-on
ATE542810T1 (de) Verfahren zur herstellung von 3,5-di-omikron-acyl-2-fluor-2-c-methyl-d-ribono gamma-lacton
ATE391115T1 (de) Verfahren zur herstellung von diketenacetalen
DK1156058T3 (da) Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf
UA100849C2 (ru) Способ репликации вируса гриппа в культуре
ITMI20032172A1 (it) Procedimento atto alla correzione dell'arricchimento di
DK1501838T3 (da) Fremgangsmåde til fremstilling af clopidogrel