ATE557082T1 - Sequenz positionen zur anpassung bei prrsv - Google Patents
Sequenz positionen zur anpassung bei prrsvInfo
- Publication number
- ATE557082T1 ATE557082T1 AT02076334T AT02076334T ATE557082T1 AT E557082 T1 ATE557082 T1 AT E557082T1 AT 02076334 T AT02076334 T AT 02076334T AT 02076334 T AT02076334 T AT 02076334T AT E557082 T1 ATE557082 T1 AT E557082T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- positions
- arterivirus
- specifically
- amino acids
- Prior art date
Links
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 title abstract 4
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 6
- 150000001413 amino acids Chemical group 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 3
- 241000867607 Chlorocebus sabaeus Species 0.000 abstract 2
- 101150034914 GP2a gene Proteins 0.000 abstract 2
- SPEFJYZGXZENAF-UHFFFAOYSA-N N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide Chemical compound C=1C(C)=CC=C(C2=3)C=1CC=3C(C(=O)NC1CCCCC1)=NN2C1=CC=C(Cl)C=C1Cl SPEFJYZGXZENAF-UHFFFAOYSA-N 0.000 abstract 2
- 230000001018 virulence Effects 0.000 abstract 2
- 230000006978 adaptation Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10061—Methods of inactivation or attenuation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10061—Methods of inactivation or attenuation
- C12N2770/10064—Methods of inactivation or attenuation by serial passage
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02076334A EP1350840B1 (en) | 2002-04-05 | 2002-04-05 | Adaptation sites of PRRSV |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE557082T1 true ATE557082T1 (de) | 2012-05-15 |
Family
ID=27838115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02076334T ATE557082T1 (de) | 2002-04-05 | 2002-04-05 | Sequenz positionen zur anpassung bei prrsv |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7312030B2 (enExample) |
| EP (1) | EP1350840B1 (enExample) |
| JP (1) | JP4477307B2 (enExample) |
| AT (1) | ATE557082T1 (enExample) |
| CA (1) | CA2424400C (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| CA2366072C (en) | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Prrsv vaccines |
| ES2348159T3 (es) | 1999-04-22 | 2010-11-30 | United States Department Of Agriculture | Vacuna contra el sindrome respiratorio y reproductivo porcino basada en el aislado ja-142. |
| TW200604526A (en) | 2004-06-18 | 2006-02-01 | Unviersity Of Minnesota | Identifying virally infected and vaccinated organisms |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| CA2587849A1 (en) | 2004-11-19 | 2006-05-26 | Intervet International B.V. | Porcine reproductive and respiratory syndrome virus strains and compositions |
| PT2369001T (pt) | 2005-06-24 | 2016-10-25 | Univ Minnesota | Vírus srrp, clones infecciosos, os seus mutantes e processos de utilização |
| CA2620667A1 (en) * | 2005-08-30 | 2007-04-12 | Board Of Regents Of The University Of Nebraska | Methods and compositions for vaccination of animals with prrsv antigens with improved immunogenicity |
| US8084594B2 (en) * | 2007-07-13 | 2011-12-27 | The United States Of America As Represented By The Secretary Of Agriculture | H2N3 influenza A viruses and methods of use |
| KR101653177B1 (ko) * | 2008-08-25 | 2016-09-01 | 베링거잉겔하임베트메디카인코퍼레이티드 | 고병원성 돼지 생식기 및 호흡기 증후군(ｈｐ ｐｒｒｓ)에 대한 백신 |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物 |
| ES2692809T3 (es) | 2011-02-17 | 2018-12-05 | Boehringer Ingelheim Vetmedica Gmbh | Nueva cepa del PRRSV europea |
| CA2827337C (en) | 2011-02-17 | 2019-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
| US9315781B2 (en) | 2011-07-29 | 2016-04-19 | Boehringer Ingelheim Vetmedica Gmbh | Infectious CDNA clone of european PRRS virus and uses thereof |
| US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
| US9579373B2 (en) | 2013-03-15 | 2017-02-28 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| CN105829528B (zh) | 2013-12-20 | 2019-10-22 | 勃林格殷格翰动物保健有限公司 | PRRS病毒变体、欧洲PRRS病毒cDNA克隆及其用途 |
-
2002
- 2002-04-05 AT AT02076334T patent/ATE557082T1/de active
- 2002-04-05 EP EP02076334A patent/EP1350840B1/en not_active Expired - Lifetime
-
2003
- 2003-04-03 CA CA2424400A patent/CA2424400C/en not_active Expired - Fee Related
- 2003-04-04 US US10/407,822 patent/US7312030B2/en not_active Expired - Lifetime
- 2003-04-04 JP JP2003102066A patent/JP4477307B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2424400A1 (en) | 2003-10-05 |
| US20030219732A1 (en) | 2003-11-27 |
| EP1350840A1 (en) | 2003-10-08 |
| JP2004121220A (ja) | 2004-04-22 |
| EP1350840B1 (en) | 2012-05-09 |
| US7312030B2 (en) | 2007-12-25 |
| CA2424400C (en) | 2012-08-21 |
| JP4477307B2 (ja) | 2010-06-09 |
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