ATE556324T1 - Verwendung von kir-genen zur vorhersage der reaktion auf eine therapie - Google Patents
Verwendung von kir-genen zur vorhersage der reaktion auf eine therapieInfo
- Publication number
- ATE556324T1 ATE556324T1 AT08860427T AT08860427T ATE556324T1 AT E556324 T1 ATE556324 T1 AT E556324T1 AT 08860427 T AT08860427 T AT 08860427T AT 08860427 T AT08860427 T AT 08860427T AT E556324 T1 ATE556324 T1 AT E556324T1
- Authority
- AT
- Austria
- Prior art keywords
- therapy
- necrosis factor
- tumour necrosis
- based therapy
- respond
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title 1
- 108050007852 Tumour necrosis factor Proteins 0.000 abstract 3
- 102000018594 Tumour necrosis factor Human genes 0.000 abstract 3
- 108010043610 KIR Receptors Proteins 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000007726 management method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012913 prioritisation Methods 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0724131.8A GB0724131D0 (en) | 2007-12-11 | 2007-12-11 | Use of KIR genes for predicting response to therapy |
| PCT/EP2008/010547 WO2009074326A2 (en) | 2007-12-11 | 2008-12-11 | Use of kir genes for predicting response to therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE556324T1 true ATE556324T1 (de) | 2012-05-15 |
Family
ID=39016390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08860427T ATE556324T1 (de) | 2007-12-11 | 2008-12-11 | Verwendung von kir-genen zur vorhersage der reaktion auf eine therapie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100323358A1 (de) |
| EP (1) | EP2232268B1 (de) |
| AT (1) | ATE556324T1 (de) |
| CA (1) | CA2709207A1 (de) |
| ES (1) | ES2385628T3 (de) |
| GB (1) | GB0724131D0 (de) |
| WO (1) | WO2009074326A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102575292B (zh) * | 2009-09-22 | 2015-07-29 | 霍夫曼-拉罗奇有限公司 | 与疾病相关的kir单元型的测定 |
| CN103209988B (zh) * | 2010-10-06 | 2016-11-09 | 圣朱德儿童研究医院 | Kir等位基因及kir-配体的基于分子决定簇的分型 |
| CN107557451A (zh) * | 2017-09-26 | 2018-01-09 | 苏州大学附属第医院 | 荧光定量PCR检测KIR2DS1‑mRNA的试剂盒所用扩增引物的制备方法 |
| CN114107475B (zh) * | 2020-08-28 | 2024-05-14 | 复旦大学附属华山医院 | Tmf1多态性位点作为基因标志物以及和甲氨蝶呤联合的银屑病试剂盒 |
| CN112725442A (zh) * | 2021-02-22 | 2021-04-30 | 深圳荻硕贝肯精准医学有限公司 | Kir3dl2基因分型试剂盒和分型方法 |
-
2007
- 2007-12-11 GB GBGB0724131.8A patent/GB0724131D0/en not_active Ceased
-
2008
- 2008-12-11 AT AT08860427T patent/ATE556324T1/de active
- 2008-12-11 CA CA2709207A patent/CA2709207A1/en not_active Abandoned
- 2008-12-11 WO PCT/EP2008/010547 patent/WO2009074326A2/en active Application Filing
- 2008-12-11 EP EP08860427A patent/EP2232268B1/de not_active Not-in-force
- 2008-12-11 ES ES08860427T patent/ES2385628T3/es active Active
- 2008-12-11 US US12/747,840 patent/US20100323358A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2232268B1 (de) | 2012-05-02 |
| WO2009074326A3 (en) | 2009-08-13 |
| WO2009074326A2 (en) | 2009-06-18 |
| ES2385628T3 (es) | 2012-07-27 |
| CA2709207A1 (en) | 2009-06-18 |
| US20100323358A1 (en) | 2010-12-23 |
| EP2232268A2 (de) | 2010-09-29 |
| GB0724131D0 (en) | 2008-01-23 |
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