ATE55598T1 - 6-ketoprostaglandin-e1-derivate. - Google Patents

6-ketoprostaglandin-e1-derivate.

Info

Publication number
ATE55598T1
ATE55598T1 AT87300755T AT87300755T ATE55598T1 AT E55598 T1 ATE55598 T1 AT E55598T1 AT 87300755 T AT87300755 T AT 87300755T AT 87300755 T AT87300755 T AT 87300755T AT E55598 T1 ATE55598 T1 AT E55598T1
Authority
AT
Austria
Prior art keywords
carbon atoms
group
unsubstituted
substituted
single bond
Prior art date
Application number
AT87300755T
Other languages
English (en)
Inventor
Hirohisa Wakatsuka
Tadao Okegawa
Yoshinobu Arai
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Application granted granted Critical
Publication of ATE55598T1 publication Critical patent/ATE55598T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
AT87300755T 1986-01-30 1987-01-28 6-ketoprostaglandin-e1-derivate. ATE55598T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1672286 1986-01-30
EP87300755A EP0232126B1 (de) 1986-01-30 1987-01-28 6-Ketoprostaglandin-E1-Derivate

Publications (1)

Publication Number Publication Date
ATE55598T1 true ATE55598T1 (de) 1990-09-15

Family

ID=11924155

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87300755T ATE55598T1 (de) 1986-01-30 1987-01-28 6-ketoprostaglandin-e1-derivate.

Country Status (7)

Country Link
US (1) US4783480A (de)
EP (1) EP0232126B1 (de)
JP (1) JPS62277352A (de)
AT (1) ATE55598T1 (de)
DE (1) DE3764277D1 (de)
ES (1) ES2029830T3 (de)
GR (1) GR3001054T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3708537A1 (de) * 1987-03-13 1988-09-22 Schering Ag 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
EP0386901A1 (de) * 1989-02-20 1990-09-12 Ono Pharmaceutical Co., Ltd. 5-Hetero-6-oxo-PGE-Derivate
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
US5288754A (en) * 1992-02-04 1994-02-22 Allergan, Inc. Polar C-1 esters of prostaglandins
WO2003013508A1 (en) * 2001-08-08 2003-02-20 Pentraxin Therapeutics Limited Therapeutic agent for depletion of an unwanted protein population from plasma
GB0119370D0 (en) * 2001-08-08 2001-10-03 Univ London Therapeutic agent
GB0313386D0 (en) * 2003-06-10 2003-07-16 Univ London Treatment of disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5013363A (de) * 1973-06-08 1975-02-12
JPS5071650A (de) * 1973-11-02 1975-06-13
JPS50140422A (de) * 1974-01-16 1975-11-11
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues

Also Published As

Publication number Publication date
EP0232126A3 (en) 1987-11-25
GR3001054T3 (en) 1992-03-20
US4783480A (en) 1988-11-08
JPS62277352A (ja) 1987-12-02
EP0232126A2 (de) 1987-08-12
DE3764277D1 (de) 1990-09-20
ES2029830T3 (es) 1992-10-01
EP0232126B1 (de) 1990-08-16

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