ATE545411T1 - Herstellungsverfahren für feststoffdispersionen - Google Patents

Herstellungsverfahren für feststoffdispersionen

Info

Publication number
ATE545411T1
ATE545411T1 AT09725902T AT09725902T ATE545411T1 AT E545411 T1 ATE545411 T1 AT E545411T1 AT 09725902 T AT09725902 T AT 09725902T AT 09725902 T AT09725902 T AT 09725902T AT E545411 T1 ATE545411 T1 AT E545411T1
Authority
AT
Austria
Prior art keywords
drug
acids
bcs class
mixture
acid
Prior art date
Application number
AT09725902T
Other languages
English (en)
Inventor
Sandrien Janssens
Den Mooter Guy Van
Original Assignee
Formac Pharmaceuticals N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Formac Pharmaceuticals N V filed Critical Formac Pharmaceuticals N V
Application granted granted Critical
Publication of ATE545411T1 publication Critical patent/ATE545411T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT09725902T 2008-03-25 2009-03-25 Herstellungsverfahren für feststoffdispersionen ATE545411T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7084008P 2008-03-25 2008-03-25
US10653608P 2008-10-17 2008-10-17
PCT/EP2009/053542 WO2009118356A2 (en) 2008-03-25 2009-03-25 Preparation method for solid disupersions

Publications (1)

Publication Number Publication Date
ATE545411T1 true ATE545411T1 (de) 2012-03-15

Family

ID=40996768

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09725902T ATE545411T1 (de) 2008-03-25 2009-03-25 Herstellungsverfahren für feststoffdispersionen

Country Status (6)

Country Link
US (1) US8216495B2 (de)
EP (1) EP2170289B1 (de)
JP (1) JP2011515444A (de)
AT (1) ATE545411T1 (de)
ES (1) ES2382618T3 (de)
WO (1) WO2009118356A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120076838A1 (en) * 2009-05-27 2012-03-29 Samyang Biopharmaceuticals Corporation Poorly soluble drug containing microsphere with improved bioavailabilty and method of preparing the same
JP6073788B2 (ja) * 2010-09-14 2017-02-01 ナノロジカ アクティエボラーグ 難水溶性医薬及び化粧品有効成分のための過飽和送達媒体
GB201115634D0 (en) 2011-09-09 2011-10-26 Univ Liverpool Compositions of lopinavir
GB201115635D0 (en) 2011-09-09 2011-10-26 Univ Liverpool Compositions of lopinavir and ritonavir
CN103655571B (zh) * 2012-09-11 2016-04-20 上海星泰医药科技有限公司 一种洛匹那韦和利托那韦复方高均匀度纳米共分散体及其制备方法
US9511341B2 (en) 2013-08-30 2016-12-06 Sunny Pharmtech Inc. Method for preparing acetazolamide sodium powder
KR102639753B1 (ko) * 2013-12-31 2024-02-22 아센디아 파마슈티컬스, 엘엘씨 난수용성 화합물용 약제학적 조성물
PT107846B (pt) * 2014-08-01 2019-03-22 Hovione Farm S A Produção de nano- partículas de dispersões sólidas amorfas por co-precipitação controlada
WO2016041992A1 (en) 2014-09-15 2016-03-24 Grace Gmbh & Co. Kg Active-loaded particulate materials for topical administration
TWI525110B (zh) * 2014-12-24 2016-03-11 財團法人工業技術研究院 聚合物、及包含其之醫藥組合物
BR112017018533B1 (pt) 2015-03-10 2023-10-03 Shionogi Inc Composição que compreende uma dispersão sólida de ospemifeno e seu método de preparação
WO2017083963A1 (en) 2015-11-18 2017-05-26 Immunovaccine Technologies Inc. Adjuvanting systems and water-free vaccine compositions comprising a polyi:c polynucleotide adjuvant and a lipid-based adjuvant
CN105832680B (zh) * 2016-05-12 2018-12-25 沈阳药科大学 一种改善螺内酯体外溶出及流动性的药物组合物
US10195214B2 (en) * 2017-03-01 2019-02-05 Corcept Therapeutics, Inc. Concomitant administration of glucocorticoid receptor modulators and CYP3A inhibitors

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
DE3839825A1 (de) * 1988-11-25 1990-06-13 Henning Berlin Gmbh Feststoffdispersionen enthaltend oxipurinol und/oder seine alkali- oder erdalkalisalze
US5985248A (en) * 1996-12-31 1999-11-16 Inhale Therapeutic Systems Processes for spray drying solutions of hydrophobic drugs and compositions thereof
DE10153934A1 (de) * 2001-11-06 2003-05-22 Basf Ag Verfahren zur Kristallisation von Profenen
DE10207427A1 (de) * 2002-02-21 2003-09-04 Basf Ag Schnelllöslicher Filmüberzug basierend auf Polyvinylalkohol-Polyether-Pfropfcopolymeren in Kombination mit Hydroxy-, Amid-, oder Esterfunktionen enthaltenden Komponenten
DE60315984T2 (de) * 2002-05-17 2008-05-29 Tibotec Pharmaceuticals Ltd. Substituierte benzisoxazolsulfonamide mit breitbändiger hiv-protease hemmender wirkung
KR100592512B1 (ko) * 2002-11-22 2006-07-03 서울약품공업(주) 탐술로신 또는 약제학적으로 허용되는 이의 염을활성성분으로 하는 서방성 배뇨장애 치료제
EP1428526A1 (de) * 2002-12-13 2004-06-16 Rijksuniversiteit Groningen Zusammensetzung zur schnellen Freisetzung von lipophilen Stoffen
KR100629771B1 (ko) * 2004-01-27 2006-09-28 씨제이 주식회사 결정성이 감소되거나 무정형화된 올티프라즈의 제조방법
MXPA06011686A (es) * 2004-04-08 2006-12-14 Wyeth Corp Ascorbato de bazedoxifeno como modulador del receptor de estrogeno selectivo.
KR100678824B1 (ko) * 2005-02-04 2007-02-05 한미약품 주식회사 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물
EP1871346A4 (de) * 2005-04-20 2012-07-18 Ctc Bio Inc Pharmazeutische zusammensetzung mit freier base aus sibutramin und herstellungsverfahren dafür
GB0607105D0 (en) * 2006-04-10 2006-05-17 Leuven K U Res & Dev Enhancing solubility and dissolution rate of poorly soluble drugs
WO2008080773A1 (de) 2006-12-29 2008-07-10 Basf Se Verfahren zur herstellung von festen dosierungsformen enthaltend pfropfcopolymere

Also Published As

Publication number Publication date
US8216495B2 (en) 2012-07-10
EP2170289B1 (de) 2012-02-15
US20110018154A1 (en) 2011-01-27
WO2009118356A2 (en) 2009-10-01
ES2382618T3 (es) 2012-06-11
WO2009118356A3 (en) 2010-02-18
JP2011515444A (ja) 2011-05-19
EP2170289A2 (de) 2010-04-07

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