ATE544474T1 - Magnetresonanz-abbildungsmittel, abbildungsmedium und verfahren zur abbildung, worin solch ein abbildungsmedium verwendet wird - Google Patents

Magnetresonanz-abbildungsmittel, abbildungsmedium und verfahren zur abbildung, worin solch ein abbildungsmedium verwendet wird

Info

Publication number
ATE544474T1
ATE544474T1 AT08864838T AT08864838T ATE544474T1 AT E544474 T1 ATE544474 T1 AT E544474T1 AT 08864838 T AT08864838 T AT 08864838T AT 08864838 T AT08864838 T AT 08864838T AT E544474 T1 ATE544474 T1 AT E544474T1
Authority
AT
Austria
Prior art keywords
imaging
medium
magnetic resonance
imaging medium
ketoisocaproate
Prior art date
Application number
AT08864838T
Other languages
English (en)
Inventor
Anna Gisselsson
Georg Hansson
Sven Mansson
T Zandt Rene In
Magnus Karlsson
Pernille Jensen
Mathilde Lerche
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of ATE544474T1 publication Critical patent/ATE544474T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/20Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT08864838T 2007-12-21 2008-12-19 Magnetresonanz-abbildungsmittel, abbildungsmedium und verfahren zur abbildung, worin solch ein abbildungsmedium verwendet wird ATE544474T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20076640 2007-12-21
PCT/EP2008/067986 WO2009080739A1 (en) 2007-12-21 2008-12-19 Mr imaging agent, imaging medium and methods of imaging wherein such an imaging medium is used

Publications (1)

Publication Number Publication Date
ATE544474T1 true ATE544474T1 (de) 2012-02-15

Family

ID=40470026

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08864838T ATE544474T1 (de) 2007-12-21 2008-12-19 Magnetresonanz-abbildungsmittel, abbildungsmedium und verfahren zur abbildung, worin solch ein abbildungsmedium verwendet wird

Country Status (7)

Country Link
US (1) US20110038804A1 (de)
EP (1) EP2222346B1 (de)
JP (1) JP5351172B2 (de)
CN (1) CN101951963B (de)
AT (1) ATE544474T1 (de)
ES (1) ES2379143T3 (de)
WO (1) WO2009080739A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5570081B2 (ja) 2012-04-27 2014-08-13 株式会社エフ・シー・シー プレス部品の成形方法、プレス部品の製造方法およびプレス部品の成形用金型
KR20150111353A (ko) * 2013-01-31 2015-10-05 브라코 이미징 에스.피.에이. Mr에서 대사 마커로서 사용되는 과분극화된 에스테르
EP3101012A1 (de) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft Neue gadoliniumchelat-verbindung zur verwendung in der magnetresonanzbildgebung
CN110035996B (zh) 2016-11-28 2022-08-09 拜耳医药股份公司 用于磁共振成像的新型高弛豫性钆螯合物
KR20210095168A (ko) 2018-11-23 2021-07-30 바이엘 악티엔게젤샤프트 조영 매체의 제형 및 그의 제조 방법
EP4090648A4 (de) * 2020-01-17 2024-06-12 The Government of The United States of America as represented by The Secretary, Department of Health and Human Services Isotope von alpha-ketoglutarat und verwandten verbindungen und deren verwendung in der hyperpolarisierten bildgebung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0513812B8 (pt) * 2004-07-30 2021-07-27 Ge Healthcare As método para produzir uma composição líquida que compreende 13c-piruvato hiperpolarizado, composição, uso da mesma, radical, e, uso do radical
WO2006011810A2 (en) * 2004-07-30 2006-02-02 Ge Healthcare As Mr imaging method for the discrimination between healthy and tumour tissue
JP5475995B2 (ja) * 2005-12-01 2014-04-16 ジーイー・ヘルスケア・アクスイェ・セルスカプ 動的核分極(dnp)法
PL1962912T3 (pl) * 2005-12-16 2013-03-29 Ge Healthcare As Sposób wytwarzania hiperpolaryzowanych karboksylanów amin organicznych
EP2117607A4 (de) * 2007-01-11 2012-08-08 Huntington Medical Res Inst Abbildungswirkstoffe und verfahren zu ihrer verwendung

Also Published As

Publication number Publication date
ES2379143T3 (es) 2012-04-23
WO2009080739A1 (en) 2009-07-02
JP5351172B2 (ja) 2013-11-27
US20110038804A1 (en) 2011-02-17
CN101951963A (zh) 2011-01-19
CN101951963B (zh) 2013-07-17
EP2222346A1 (de) 2010-09-01
EP2222346B1 (de) 2012-02-08
JP2011506015A (ja) 2011-03-03

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