ATE540957T1 - Bicyclische peptidomimetikum-inhibitoren von aspartylproteasen zur behandlung von infektionskrankheiten - Google Patents

Bicyclische peptidomimetikum-inhibitoren von aspartylproteasen zur behandlung von infektionskrankheiten

Info

Publication number
ATE540957T1
ATE540957T1 AT08169901T AT08169901T ATE540957T1 AT E540957 T1 ATE540957 T1 AT E540957T1 AT 08169901 T AT08169901 T AT 08169901T AT 08169901 T AT08169901 T AT 08169901T AT E540957 T1 ATE540957 T1 AT E540957T1
Authority
AT
Austria
Prior art keywords
treatment
peptidomimetics
bicyclic
inhibitors
infectious diseases
Prior art date
Application number
AT08169901T
Other languages
English (en)
Inventor
Antonio Cassone
Bernardis Flavia De
Enrico Garaci
Andrea Trabocchi
Antonio Guarna
Original Assignee
Univ Firenze
Inst Superiore Di Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Firenze, Inst Superiore Di Sanita filed Critical Univ Firenze
Application granted granted Critical
Publication of ATE540957T1 publication Critical patent/ATE540957T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT08169901T 2008-11-25 2008-11-25 Bicyclische peptidomimetikum-inhibitoren von aspartylproteasen zur behandlung von infektionskrankheiten ATE540957T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08169901A EP2189462B9 (de) 2008-11-25 2008-11-25 Bicyclische Peptidomimetikum-Inhibitoren von Aspartylproteasen zur Behandlung von Infektionskrankheiten

Publications (1)

Publication Number Publication Date
ATE540957T1 true ATE540957T1 (de) 2012-01-15

Family

ID=40383580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08169901T ATE540957T1 (de) 2008-11-25 2008-11-25 Bicyclische peptidomimetikum-inhibitoren von aspartylproteasen zur behandlung von infektionskrankheiten

Country Status (7)

Country Link
US (1) US8445484B2 (de)
EP (1) EP2189462B9 (de)
JP (1) JP5660633B2 (de)
CN (1) CN102224159A (de)
AT (1) ATE540957T1 (de)
ES (1) ES2380613T3 (de)
WO (1) WO2010060904A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20120062A1 (it) * 2012-03-21 2013-09-22 Minerva Patents S A Componenti per il trattamento di malattie correlate a ischemia-riperfusione.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20020107A1 (it) 2002-06-19 2003-12-19 Antonio Guarna Composizioni farmaceutiche atte all'uso nel trattamento di patologie correlate all'azione di neutrofine e composti attivi in esse contenuti
CA2521938A1 (en) * 2003-04-30 2004-11-11 Actelion Pharmaceuticals Ltd 9-azabicyclo[3.3.1]non-6-ene derivatives with a heteroatom at the 3-position as renin inhibitors

Also Published As

Publication number Publication date
ES2380613T9 (es) 2013-03-25
ES2380613T3 (es) 2012-05-16
EP2189462A1 (de) 2010-05-26
US8445484B2 (en) 2013-05-21
EP2189462B1 (de) 2012-01-11
WO2010060904A1 (en) 2010-06-03
JP5660633B2 (ja) 2015-01-28
CN102224159A (zh) 2011-10-19
EP2189462B9 (de) 2012-06-13
JP2012509863A (ja) 2012-04-26
US20110237577A1 (en) 2011-09-29

Similar Documents

Publication Publication Date Title
ATE506951T1 (de) Als inhibitoren von beta-secretase aktive tertiäre carbinamine mit substituierten heterocyclen zur behandlung der alzheimer- krankheit
EA201100119A1 (ru) Химические соединения 251
ATE538651T1 (de) Spiropiperidininhibitoren von beta-secretase zur behandlung von alzheimer-krankheit
EA201170508A1 (ru) Производные 1-амино-2-циклобутилэтилбороновой кислоты
MY148851A (en) Dihydropyridine derivatives as useful as protein kinase inhibitors
EA201170963A1 (ru) Ингибиторы поли(адф-рибозо)полимеразы (parp)
AU2011338389A8 (en) Bicyclic compounds as Pim inhibitors
UA110612C2 (uk) Похідні 1-аміно-2-циклопропілетилборонової кислоти
NO20084652L (no) Deazapuriner anvendelige som inhibitorer av januskinaser
EA200870019A1 (ru) Лактамовые соединения и способы их применения
EA201100138A1 (ru) 4-феноксиметилпиперидины в качестве модуляторов активности gpr119
TW200728305A (en) Spiropiperidine beta-sectetase inhibitors for the treatment of alzheimer's disease
MY161991A (en) Proteasome inhibitors
MY155649A (en) Pyridyloxyindoles inhibitors of vegf-r2 and use thereof for treatment of disease
UA103321C2 (ru) Производные тиенопиридона как активаторы amp-активированной протеинкиназы (амрк)
BR112012018386A8 (pt) "inibidores isoindolinona de fosfatidilinositol 3-quinase"
EA200602062A1 (ru) Амидосоединения и их применение в качестве фармацевтических средств
PH12013502262A1 (en) Spiro-[1,3]-oxazines and spiro-[1,4]-oxazepines as bace1 and/or bace2 inhibitors
ATE419859T1 (de) Verwendung von probiotischen bakterien zur herstellung von topischen zusammensetzungen zum schutz der haut
EP2135858A4 (de) Zusammensetzung zur behandlung von infektionserkrankungen
MX2009006327A (es) Compuestos heterociclicos y metodos de uso de los mismos.
EA201000329A1 (ru) Циклические депсипептиды
MX2009006170A (es) Compuestos y composiciones como inhibidores de cinasa.
PH12012502070A1 (en) Inhibitors of protein tyrosine kinase activity and use thereof to treat ophthalmic disorders
ATE517873T1 (de) 6-oxo-1,6-dihydropyrimidin-2-yle bei der behandlung proliferativer krankheiten