ATE540051T1 - Age-inhibitoren - Google Patents
Age-inhibitorenInfo
- Publication number
- ATE540051T1 ATE540051T1 AT06725441T AT06725441T ATE540051T1 AT E540051 T1 ATE540051 T1 AT E540051T1 AT 06725441 T AT06725441 T AT 06725441T AT 06725441 T AT06725441 T AT 06725441T AT E540051 T1 ATE540051 T1 AT E540051T1
- Authority
- AT
- Austria
- Prior art keywords
- halogen atoms
- groups
- group
- amino acid
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0503176A FR2883873B1 (fr) | 2005-03-31 | 2005-03-31 | Inhibiteurs d'age |
PCT/EP2006/061191 WO2006103274A1 (fr) | 2005-03-31 | 2006-03-30 | Inhibiteurs d'age |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE540051T1 true ATE540051T1 (de) | 2012-01-15 |
Family
ID=34955359
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06725441T ATE540051T1 (de) | 2005-03-31 | 2006-03-30 | Age-inhibitoren |
Country Status (16)
Country | Link |
---|---|
US (2) | US20080249030A1 (de) |
EP (1) | EP1863832B1 (de) |
JP (1) | JP4695186B2 (de) |
KR (2) | KR101536839B1 (de) |
CN (1) | CN101268093B (de) |
AT (1) | ATE540051T1 (de) |
AU (1) | AU2006228163A1 (de) |
BR (1) | BRPI0609783A8 (de) |
CA (1) | CA2603386C (de) |
EA (1) | EA200702104A1 (de) |
FR (1) | FR2883873B1 (de) |
GE (1) | GEP20104882B (de) |
MA (1) | MA29416B1 (de) |
MX (1) | MX2007012238A (de) |
WO (1) | WO2006103274A1 (de) |
ZA (1) | ZA200708835B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101646416B (zh) * | 2007-03-20 | 2011-08-17 | 株式会社资生堂 | 皮肤外用组合物 |
WO2010136182A1 (en) * | 2009-05-29 | 2010-12-02 | Ruprecht-Karls-Universität Heidelberg | Methylglyoxal-scavenging compounds and their use for the prevention and treatment of pain and/or hyperalgesia |
JP5787339B2 (ja) * | 2009-12-28 | 2015-09-30 | 学校法人福岡大学 | 糖尿病前症の検査方法 |
FR2981073B1 (fr) * | 2011-10-07 | 2013-12-27 | Pharmamens | Composes piegeurs d'alpha-oxoaldehydes et d'aldehydes alpha, beta-insatures, compositions les contenant et leurs utilisations dans des traitements de maladies liees a l'accumulation des age et ale. |
US20160024233A1 (en) * | 2013-03-15 | 2016-01-28 | Genzyme Corporation | Sequestrants of advanced glycation end product (age) precursors |
WO2016064234A1 (ko) * | 2014-10-22 | 2016-04-28 | (주)아모레퍼시픽 | 라텍스 발포폼을 포함하는 화장료 조성물 담체 |
FR3038605B1 (fr) * | 2015-07-06 | 2018-08-24 | Universite Amiens Picardie Jules Verne | Diamines primaires vicinales associees a des motifs chelateurs de metaux et/ou de radicaux libres, actives contre les stress carbonyle et oxydant et leur utilisation |
JP6553491B2 (ja) * | 2015-11-26 | 2019-07-31 | オリエンタル酵母工業株式会社 | 最終糖化産物(AGEs)が関連する疾患の罹患又はそのリスクを予測する方法 |
CN112898342A (zh) * | 2017-06-26 | 2021-06-04 | 上海日馨生物科技有限公司 | 苯磷硫胺衍生物、制备方法及其药物组合物 |
TWI685338B (zh) | 2017-12-14 | 2020-02-21 | 柯瑞 伊里阿斯 J | 使用非可吸收性口服投予之化合物之包括第2型糖尿病、脂肪肝炎及相關病況之人類代謝症候群之預防及治療 |
WO2020071258A1 (ja) * | 2018-10-03 | 2020-04-09 | 味の素株式会社 | タンパク質糖化抑制剤 |
CN112881581B (zh) * | 2021-01-15 | 2022-04-01 | 中国海洋大学 | 一种定量检测水产品中吡咯素和甲基乙二醛氢咪唑酮的方法 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4908446A (en) * | 1985-11-14 | 1990-03-13 | The Rockefeller University | Inhibitors of nonenzymatic cross-linking |
US4758583A (en) * | 1984-03-19 | 1988-07-19 | The Rockefeller University | Method and agents for inhibiting protein aging |
US4900747A (en) * | 1984-03-19 | 1990-02-13 | The Rockefeller University | Method and agents for removing advanced glycosylation endproducts |
FI890918A (fi) * | 1988-03-11 | 1989-09-12 | Eisai Co Ltd | Polypeptider. |
US5232735A (en) | 1990-06-01 | 1993-08-03 | Bioresearch, Inc. | Ingestibles containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers |
CA2104594C (en) * | 1991-02-22 | 2004-05-11 | Howard K. Shapiro | Use of pharmaceutical compounds in the treatment of symptoms of disorders related to neurological diseases and etiologically related symptomology |
JPH07500580A (ja) * | 1991-09-09 | 1995-01-19 | ペプテック リミテッド | 糖尿病の合併症及び病因の処理方法 |
HUT68764A (en) * | 1991-11-27 | 1995-07-28 | Bioresearch Inc | Eatable taste modifiers |
GB9200415D0 (en) * | 1992-01-09 | 1992-02-26 | Bagshawe Kenneth D | Inactivation of cytotoxic drugs |
US5780588A (en) * | 1993-01-26 | 1998-07-14 | Arizona Board Of Regents | Elucidation and synthesis of selected pentapeptides |
US5629174A (en) * | 1993-07-26 | 1997-05-13 | Cor Therapeutics, Inc. | Recombinant C140 receptor |
NZ334998A (en) * | 1995-01-25 | 2000-11-24 | Cor Therapeutics Inc | Use of an agonist or antagonist for inhibiting the expression of a C140 receptor |
DK61695A (da) * | 1995-06-01 | 1996-12-02 | Aarhus Oliefabrik As | Kakaoflavouraktive peptider, DNA som koder for dem, fremgangsmåder til fremstilling af peptiderne og deres anvendelse til frembringelse af kakaoflavour |
US6083758A (en) * | 1997-04-09 | 2000-07-04 | California Institute Of Technology | Method for screening peptides for metal coordinating properties and fluorescent chemosensors derived therefrom |
WO2000059875A2 (en) * | 1999-04-05 | 2000-10-12 | City Of Hope | Novel inhibitors of formation of advanced glycation endproducts (age's) |
US6605642B2 (en) * | 1999-04-05 | 2003-08-12 | City Of Hope | Inhibitors of formation of advanced glycation endproducts (AGES) |
US6787566B2 (en) * | 1999-04-05 | 2004-09-07 | City Of Hope | Breakers of advanced glycation endproducts |
US6589944B1 (en) | 1999-04-05 | 2003-07-08 | City Of Hope | Breakers of advanced glycation endproducts |
CA2371391A1 (en) * | 1999-04-29 | 2000-11-09 | City Of Hope | Pentoxifylline, pioglitazone and metformin are inhibitors of formation of advanced glycation endproducts (age's) |
AU6842401A (en) * | 2000-06-14 | 2001-12-24 | Clontech Lab Inc | Fluorescent timer proteins and methods for their use |
DE10048260A1 (de) * | 2000-09-29 | 2002-04-11 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung |
DE60233231D1 (de) * | 2001-05-15 | 2009-09-17 | Ortho Mcneil Janssen Pharm | Ex-vivo-priming zur erzeugung cd40-ligand spezifischer zytotoxischer t-lymphozyten zur behandlung von autoimmun- und allergischen erkrankungen |
EP1412324A4 (de) * | 2001-06-11 | 2004-09-29 | Xenoport Inc | Aminosäurekonjugate, die anhaltende systemische konzentrationen von gaba-analoga ergeben |
US20030135023A1 (en) * | 2001-06-27 | 2003-07-17 | Hans-Ulrich Demuth | Peptide structures useful for competitive modulation of dipeptidyl peptidase IV catalysis |
MXPA04003527A (es) * | 2001-10-15 | 2005-06-20 | Barnes Jewish Hospital | Compuestos de antiresorcion osea. |
ATE510852T1 (de) * | 2001-10-30 | 2011-06-15 | Dsm Ip Assets Bv | Dermopharmazeutisch und kosmetisch wirksame oligopeptide |
GB2403222A (en) * | 2002-04-01 | 2004-12-29 | Utah Ventures Ii L P | Tissue-specific endothelial membrane proteins |
JP2005537245A (ja) * | 2002-06-26 | 2005-12-08 | エントレメッド インコーポレイテッド | タンパク質活性化レセプターのアンタゴニストを含む組成物および方法 |
-
2005
- 2005-03-31 FR FR0503176A patent/FR2883873B1/fr not_active Expired - Fee Related
-
2006
- 2006-03-30 CN CN2006800149170A patent/CN101268093B/zh not_active Expired - Fee Related
- 2006-03-30 GE GEAP200610342A patent/GEP20104882B/en unknown
- 2006-03-30 EA EA200702104A patent/EA200702104A1/ru unknown
- 2006-03-30 CA CA2603386A patent/CA2603386C/fr not_active Expired - Fee Related
- 2006-03-30 BR BRPI0609783A patent/BRPI0609783A8/pt not_active Application Discontinuation
- 2006-03-30 KR KR1020137021845A patent/KR101536839B1/ko active IP Right Grant
- 2006-03-30 AU AU2006228163A patent/AU2006228163A1/en not_active Abandoned
- 2006-03-30 AT AT06725441T patent/ATE540051T1/de active
- 2006-03-30 MX MX2007012238A patent/MX2007012238A/es unknown
- 2006-03-30 JP JP2008503523A patent/JP4695186B2/ja not_active Expired - Fee Related
- 2006-03-30 WO PCT/EP2006/061191 patent/WO2006103274A1/fr active Application Filing
- 2006-03-30 US US11/909,761 patent/US20080249030A1/en not_active Abandoned
- 2006-03-30 EP EP06725441A patent/EP1863832B1/de active Active
-
2007
- 2007-10-16 ZA ZA200708835A patent/ZA200708835B/xx unknown
- 2007-10-16 KR KR1020077023743A patent/KR101343929B1/ko active IP Right Grant
- 2007-10-30 MA MA30340A patent/MA29416B1/fr unknown
-
2012
- 2012-04-02 US US13/437,491 patent/US9512176B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2883873A1 (fr) | 2006-10-06 |
MA29416B1 (fr) | 2008-04-01 |
CA2603386C (fr) | 2018-03-06 |
MX2007012238A (es) | 2008-03-18 |
EA200702104A1 (ru) | 2008-02-28 |
CN101268093A (zh) | 2008-09-17 |
EP1863832A1 (de) | 2007-12-12 |
US9512176B2 (en) | 2016-12-06 |
ZA200708835B (en) | 2009-09-30 |
US20120252866A1 (en) | 2012-10-04 |
KR101343929B1 (ko) | 2013-12-24 |
KR20130110222A (ko) | 2013-10-08 |
JP4695186B2 (ja) | 2011-06-08 |
KR20080006557A (ko) | 2008-01-16 |
WO2006103274A9 (fr) | 2007-01-18 |
CN101268093B (zh) | 2013-04-03 |
EP1863832B1 (de) | 2012-01-04 |
US20080249030A1 (en) | 2008-10-09 |
CA2603386A1 (fr) | 2006-10-05 |
FR2883873B1 (fr) | 2009-07-10 |
KR101536839B1 (ko) | 2015-07-14 |
WO2006103274A8 (fr) | 2007-05-03 |
JP2008534557A (ja) | 2008-08-28 |
WO2006103274A1 (fr) | 2006-10-05 |
BRPI0609783A2 (pt) | 2011-10-11 |
AU2006228163A1 (en) | 2006-10-05 |
BRPI0609783A8 (pt) | 2018-03-13 |
GEP20104882B (en) | 2010-01-11 |
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