ATE536861T1 - Bioerodierbare arzneimittelabgabesysteme mit verzögerter freisetzung - Google Patents

Bioerodierbare arzneimittelabgabesysteme mit verzögerter freisetzung

Info

Publication number
ATE536861T1
ATE536861T1 AT04777134T AT04777134T ATE536861T1 AT E536861 T1 ATE536861 T1 AT E536861T1 AT 04777134 T AT04777134 T AT 04777134T AT 04777134 T AT04777134 T AT 04777134T AT E536861 T1 ATE536861 T1 AT E536861T1
Authority
AT
Austria
Prior art keywords
drug delivery
sustained release
delivery systems
release drug
bioerodable
Prior art date
Application number
AT04777134T
Other languages
English (en)
Inventor
Paul Ashton
Jianbing Chen
Hong Guo
Dongling Su
Original Assignee
Control Delivery Sys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Control Delivery Sys Inc filed Critical Control Delivery Sys Inc
Application granted granted Critical
Publication of ATE536861T1 publication Critical patent/ATE536861T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
AT04777134T 2003-06-26 2004-06-25 Bioerodierbare arzneimittelabgabesysteme mit verzögerter freisetzung ATE536861T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48331603P 2003-06-26 2003-06-26
US50194703P 2003-09-11 2003-09-11
US57530704P 2004-05-28 2004-05-28
PCT/US2004/020547 WO2005000268A2 (en) 2003-06-26 2004-06-25 Bioerodible sustained release drug delivery systems

Publications (1)

Publication Number Publication Date
ATE536861T1 true ATE536861T1 (de) 2011-12-15

Family

ID=33556435

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04777134T ATE536861T1 (de) 2003-06-26 2004-06-25 Bioerodierbare arzneimittelabgabesysteme mit verzögerter freisetzung

Country Status (10)

Country Link
US (2) US8815284B2 (de)
EP (1) EP1635787B1 (de)
JP (3) JP5628467B2 (de)
AR (1) AR047552A1 (de)
AT (1) ATE536861T1 (de)
CA (1) CA2530113C (de)
DK (1) DK1635787T3 (de)
ES (1) ES2379466T3 (de)
TW (1) TWI367103B (de)
WO (1) WO2005000268A2 (de)

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KR101852042B1 (ko) 2008-04-02 2018-04-25 사이토크로마 인코포레이티드 비타민 ｄ 결핍 및 관련 장애에 유용한 방법, 조성물, 용도 및 키트
US8956642B2 (en) * 2008-04-18 2015-02-17 Medtronic, Inc. Bupivacaine formulation in a polyorthoester carrier
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US8858983B2 (en) 2009-04-30 2014-10-14 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
ES2783980T3 (es) 2010-03-29 2020-09-21 Opko Ireland Global Holdings Ltd Métodos y composiciones para la reducción de niveles de paratiroides
US8911427B2 (en) * 2010-12-28 2014-12-16 Medtronic, Inc. Therapeutic agent reservoir delivery system
CN105688188A (zh) 2011-11-18 2016-06-22 瑞泽恩制药公司 聚合物蛋白微粒
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
SG11201700858RA (en) 2014-08-07 2017-03-30 Opko Ireland Global Holdings Ltd Adjunctive therapy with 25-hydroxyvitamin d
EP3858329A1 (de) * 2014-12-10 2021-08-04 Incept, LLC Hydrogel-wirkstofffreisetzungsimplantate
AU2016340072B2 (en) * 2015-10-16 2021-10-28 Regeneron Pharmaceuticals, Inc. Stable protein compositions
WO2017083779A1 (en) 2015-11-12 2017-05-18 Graybug Vision, Inc. Aggregating microparticles for therapy
TWI747893B (zh) 2016-03-28 2021-12-01 愛爾蘭商歐科愛爾蘭全球控股股份有限公司 維生素ｄ治療之方法
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Also Published As

Publication number Publication date
US20140363482A1 (en) 2014-12-11
TWI367103B (en) 2012-07-01
WO2005000268A3 (en) 2005-08-18
US20050025834A1 (en) 2005-02-03
EP1635787A2 (de) 2006-03-22
CA2530113A1 (en) 2005-01-06
CA2530113C (en) 2013-08-13
ES2379466T3 (es) 2012-04-26
JP2011093944A (ja) 2011-05-12
JP2014205713A (ja) 2014-10-30
US10300114B2 (en) 2019-05-28
WO2005000268A2 (en) 2005-01-06
US8815284B2 (en) 2014-08-26
JP5628467B2 (ja) 2014-11-19
AR047552A1 (es) 2006-01-25
TW200515919A (en) 2005-05-16
EP1635787B1 (de) 2011-12-14
DK1635787T3 (da) 2012-03-26
JP2007537977A (ja) 2007-12-27

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