ATE533498T1 - Verfahren zur herstellung eines apyrogenen immunmodulators - Google Patents
Verfahren zur herstellung eines apyrogenen immunmodulatorsInfo
- Publication number
- ATE533498T1 ATE533498T1 AT07866932T AT07866932T ATE533498T1 AT E533498 T1 ATE533498 T1 AT E533498T1 AT 07866932 T AT07866932 T AT 07866932T AT 07866932 T AT07866932 T AT 07866932T AT E533498 T1 ATE533498 T1 AT E533498T1
- Authority
- AT
- Austria
- Prior art keywords
- solution
- centrifuging
- liquid phase
- homogenizing
- precipitate
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical class [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 3
- 239000007791 liquid phase Substances 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 239000002594 sorbent Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 241000881711 Acipenser sturio Species 0.000 abstract 1
- 241000972773 Aulopiformes Species 0.000 abstract 1
- 108091026806 Desoxyribonucleate Proteins 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 239000000919 ceramic Substances 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 238000000227 grinding Methods 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 230000002584 immunomodulator Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 235000019515 salmon Nutrition 0.000 abstract 1
- 239000012266 salt solution Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 238000009210 therapy by ultrasound Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006138863/15A RU2309759C1 (ru) | 2006-11-03 | 2006-11-03 | Способ получения апирогенного иммуномодулятора |
| PCT/RU2007/000547 WO2008054247A1 (fr) | 2006-11-03 | 2007-10-09 | Procédé de production d'un immunomodulateur apyrogénique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE533498T1 true ATE533498T1 (de) | 2011-12-15 |
Family
ID=38958163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07866932T ATE533498T1 (de) | 2006-11-03 | 2007-10-09 | Verfahren zur herstellung eines apyrogenen immunmodulators |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2087897B1 (de) |
| AT (1) | ATE533498T1 (de) |
| RU (1) | RU2309759C1 (de) |
| WO (1) | WO2008054247A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2651043C1 (ru) * | 2016-12-08 | 2018-04-18 | Ладыгин Александр Евгеньевич | Натрия дезоксирибонуклеат, таблетки для рассасывания, сублингвальные и способ их получения |
| RU2673802C1 (ru) * | 2018-02-13 | 2018-11-30 | Общество с ограниченной ответственностью "Фармацевтический завод иммунных лекарственных средств" | Способ производства стерильной фармацевтической субстанции |
| RU2749007C1 (ru) * | 2020-03-20 | 2021-06-02 | Александр Евгеньевич Ладыгин | Способ получения лекарственного препарата на основе натрия дезоксирибонуклеата |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2017496C1 (ru) * | 1990-12-28 | 1994-08-15 | Юрий Петрович Вайнберг | Способ выделения натриевой соли днк |
| RU2005724C1 (ru) * | 1993-04-29 | 1994-01-15 | Юрий Петрович Вайнберг | Способ производства натриевой соли дезоксирибонуклеиновой кислоты из животного сырья и установка для его осуществления |
| RU2172632C1 (ru) * | 2000-12-01 | 2001-08-27 | Каплина Элли Николаевна | Способ получения иммунотропного противовирусного препарата |
| RU2236853C1 (ru) * | 2003-12-30 | 2004-09-27 | Каплина Элли Николаевна | Способ производства иммунотропного стерильного апирогенного толерантного препарата на основе натриевой соли низкомолекулярной нативной дезоксирибонуклеиновой кислоты |
-
2006
- 2006-11-03 RU RU2006138863/15A patent/RU2309759C1/ru active
-
2007
- 2007-10-09 WO PCT/RU2007/000547 patent/WO2008054247A1/ru not_active Ceased
- 2007-10-09 EP EP07866932A patent/EP2087897B1/de not_active Not-in-force
- 2007-10-09 AT AT07866932T patent/ATE533498T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2309759C1 (ru) | 2007-11-10 |
| EP2087897B1 (de) | 2011-11-16 |
| EP2087897A4 (de) | 2010-06-02 |
| WO2008054247A1 (fr) | 2008-05-08 |
| EP2087897A1 (de) | 2009-08-12 |
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