ATE532863T1 - Verfahren zur anzucht von myokardzellen - Google Patents
Verfahren zur anzucht von myokardzellenInfo
- Publication number
- ATE532863T1 ATE532863T1 AT04818986T AT04818986T ATE532863T1 AT E532863 T1 ATE532863 T1 AT E532863T1 AT 04818986 T AT04818986 T AT 04818986T AT 04818986 T AT04818986 T AT 04818986T AT E532863 T1 ATE532863 T1 AT E532863T1
- Authority
- AT
- Austria
- Prior art keywords
- cip
- kip family
- family protein
- production
- function
- Prior art date
Links
- 230000002107 myocardial effect Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 6
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108050006400 Cyclin Proteins 0.000 abstract 2
- 210000004413 cardiac myocyte Anatomy 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 102000016736 Cyclin Human genes 0.000 abstract 1
- 102000000577 Cyclin-Dependent Kinase Inhibitor p27 Human genes 0.000 abstract 1
- 108010016777 Cyclin-Dependent Kinase Inhibitor p27 Proteins 0.000 abstract 1
- 108090000266 Cyclin-dependent kinases Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Plant Pathology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003391708 | 2003-11-21 | ||
| JP2004246533 | 2004-08-26 | ||
| PCT/JP2004/017274 WO2005049822A1 (ja) | 2003-11-21 | 2004-11-19 | 心筋細胞の増殖方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE532863T1 true ATE532863T1 (de) | 2011-11-15 |
Family
ID=34622192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04818986T ATE532863T1 (de) | 2003-11-21 | 2004-11-19 | Verfahren zur anzucht von myokardzellen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070009496A1 (de) |
| EP (1) | EP1693451B1 (de) |
| JP (1) | JP4809061B2 (de) |
| KR (1) | KR101169980B1 (de) |
| CN (1) | CN1882687B (de) |
| AT (1) | ATE532863T1 (de) |
| AU (1) | AU2004291809B2 (de) |
| BR (1) | BRPI0416732A (de) |
| CA (1) | CA2545049A1 (de) |
| DK (1) | DK1693451T3 (de) |
| ES (1) | ES2376239T3 (de) |
| IL (1) | IL175264A0 (de) |
| RU (1) | RU2378375C2 (de) |
| SG (1) | SG148197A1 (de) |
| WO (1) | WO2005049822A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090285791A1 (en) * | 2008-05-15 | 2009-11-19 | Sbarro Health Research Organization, Inc. | Regenerating and enhancing development of muscle tissue |
| EP2545941A4 (de) * | 2010-03-12 | 2013-10-23 | Daiichi Sankyo Co Ltd | Verfahren zur proliferation von cardiomyozyten mithilfe von mikro-rna |
| WO2012067266A1 (en) | 2010-11-17 | 2012-05-24 | Kyoto University | Cardiomyocyte- and/or cardiac progenitor cell-proliferating agent and method for proliferating cardiomyocytes and/or cardiac progenitor cells |
| RU2466391C1 (ru) * | 2011-03-28 | 2012-11-10 | Государственное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России) | Способ диагностики рецидивирующей кровопотери |
| US9868937B2 (en) | 2011-05-26 | 2018-01-16 | University Of Washington | Cell and gene based methods to improve cardiac function |
| CN102382127A (zh) * | 2011-09-23 | 2012-03-21 | 复旦大学 | 特异性促进心肌细胞发生增殖的心肌小分子化合物及其应用 |
| JPWO2014038655A1 (ja) * | 2012-09-07 | 2016-08-12 | 国立大学法人京都大学 | 腸上皮由来体性幹細胞の製造方法 |
| WO2016134293A1 (en) | 2015-02-20 | 2016-08-25 | Baylor College Of Medicine | p63 INACTIVATION FOR THE TREATMENT OF HEART FAILURE |
| CN107847523B (zh) * | 2015-04-07 | 2022-03-11 | J·大卫格莱斯顿学会(根据J·大卫格莱斯顿意愿建立的遗嘱信托) | 用于诱导有丝分裂后细胞的细胞分裂的方法 |
| CN110907644B (zh) * | 2019-12-11 | 2023-01-06 | 深圳市达科为生物工程有限公司 | 多种细胞鉴定试剂盒及操作方法 |
| CN113061573B (zh) * | 2021-05-21 | 2023-03-24 | 苏州大学 | 间歇性饥饿促进心肌细胞成熟的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3875990B2 (ja) * | 1993-10-25 | 2007-01-31 | カンジ，インコーポレイテッド | 組換えアデノウイルスベクターおよび使用方法 |
| GB9417366D0 (en) * | 1994-08-26 | 1994-10-19 | Prolifix Ltd | Cell cycle regulated repressor and DNA element |
| AU1711100A (en) * | 1998-11-02 | 2000-05-22 | Regents Of The University Of California, The | A method for inhibition of phospholamban activity for the treatment of cardiac disease and heart failure |
| US7795032B2 (en) * | 2001-05-17 | 2010-09-14 | Masaaki Ikeda | Methods for proliferating cardiomyocytes and recombinant vectors therefor |
| US20030199464A1 (en) * | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
-
2004
- 2004-11-19 BR BRPI0416732-5A patent/BRPI0416732A/pt active Search and Examination
- 2004-11-19 US US10/580,248 patent/US20070009496A1/en not_active Abandoned
- 2004-11-19 DK DK04818986.4T patent/DK1693451T3/da active
- 2004-11-19 RU RU2006121980/13A patent/RU2378375C2/ru not_active IP Right Cessation
- 2004-11-19 ES ES04818986T patent/ES2376239T3/es not_active Expired - Lifetime
- 2004-11-19 JP JP2005515664A patent/JP4809061B2/ja not_active Expired - Fee Related
- 2004-11-19 EP EP04818986A patent/EP1693451B1/de not_active Expired - Lifetime
- 2004-11-19 AU AU2004291809A patent/AU2004291809B2/en not_active Ceased
- 2004-11-19 WO PCT/JP2004/017274 patent/WO2005049822A1/ja not_active Ceased
- 2004-11-19 SG SG200808669-6A patent/SG148197A1/en unknown
- 2004-11-19 KR KR1020067009795A patent/KR101169980B1/ko not_active Expired - Fee Related
- 2004-11-19 CN CN2004800344225A patent/CN1882687B/zh not_active Expired - Fee Related
- 2004-11-19 AT AT04818986T patent/ATE532863T1/de active
- 2004-11-19 CA CA002545049A patent/CA2545049A1/en not_active Abandoned
-
2006
- 2006-04-27 IL IL175264A patent/IL175264A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1693451T3 (da) | 2012-02-13 |
| KR20060125760A (ko) | 2006-12-06 |
| WO2005049822A1 (ja) | 2005-06-02 |
| US20070009496A1 (en) | 2007-01-11 |
| BRPI0416732A (pt) | 2007-01-16 |
| JP4809061B2 (ja) | 2011-11-02 |
| RU2378375C2 (ru) | 2010-01-10 |
| KR101169980B1 (ko) | 2012-07-31 |
| SG148197A1 (en) | 2008-12-31 |
| IL175264A0 (en) | 2006-09-05 |
| CN1882687A (zh) | 2006-12-20 |
| EP1693451A4 (de) | 2007-11-07 |
| RU2006121980A (ru) | 2007-12-27 |
| AU2004291809B2 (en) | 2010-05-20 |
| EP1693451B1 (de) | 2011-11-09 |
| CA2545049A1 (en) | 2005-06-02 |
| JPWO2005049822A1 (ja) | 2007-06-07 |
| AU2004291809A1 (en) | 2005-06-02 |
| CN1882687B (zh) | 2012-07-04 |
| EP1693451A1 (de) | 2006-08-23 |
| ES2376239T3 (es) | 2012-03-12 |
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