ATE527263T1 - Kristalline formen von (3r,4r)-4-amino-1-ää4-ä(3- methoxyphenyl)aminoüpyrrolä2,1-füä1,2,4ütriazin 5-ylümethylü-piperidin-3-ol - Google Patents

Kristalline formen von (3r,4r)-4-amino-1-ää4-ä(3- methoxyphenyl)aminoüpyrrolä2,1-füä1,2,4ütriazin 5-ylümethylü-piperidin-3-ol

Info

Publication number
ATE527263T1
ATE527263T1 AT07757088T AT07757088T ATE527263T1 AT E527263 T1 ATE527263 T1 AT E527263T1 AT 07757088 T AT07757088 T AT 07757088T AT 07757088 T AT07757088 T AT 07757088T AT E527263 T1 ATE527263 T1 AT E527263T1
Authority
AT
Austria
Prior art keywords
amino
piperidin
methoxyphenyl
crystalline forms
ylümethylü
Prior art date
Application number
AT07757088T
Other languages
English (en)
Inventor
Chenkou Wei
Derek Norris
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE527263T1 publication Critical patent/ATE527263T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT07757088T 2006-02-16 2007-02-16 Kristalline formen von (3r,4r)-4-amino-1-ää4-ä(3- methoxyphenyl)aminoüpyrrolä2,1-füä1,2,4ütriazin 5-ylümethylü-piperidin-3-ol ATE527263T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77392306P 2006-02-16 2006-02-16
PCT/US2007/062276 WO2007095632A1 (en) 2006-02-16 2007-02-16 Crystalline forms of (3r,4r)-4-amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methol]piperidin-3-ol

Publications (1)

Publication Number Publication Date
ATE527263T1 true ATE527263T1 (de) 2011-10-15

Family

ID=38093387

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07757088T ATE527263T1 (de) 2006-02-16 2007-02-16 Kristalline formen von (3r,4r)-4-amino-1-ää4-ä(3- methoxyphenyl)aminoüpyrrolä2,1-füä1,2,4ütriazin 5-ylümethylü-piperidin-3-ol

Country Status (8)

Country Link
US (1) US8063208B2 (de)
EP (1) EP1989207B1 (de)
JP (1) JP2009527491A (de)
CN (1) CN101384600B (de)
AT (1) ATE527263T1 (de)
ES (1) ES2372315T3 (de)
NO (1) NO20083509L (de)
WO (1) WO2007095632A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201035100A (en) 2008-12-19 2010-10-01 Cephalon Inc Pyrrolotriazines as ALK and JAK2 inhibitors

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2163399A1 (en) 1994-11-24 1996-05-25 Katsuhiro Kawano Triazine derivative, chymase activity inhibitor and nitric oxide production inhibitor
KR20000035934A (ko) 1996-08-28 2000-06-26 디. 제이. 우드, 스피겔 알렌 제이 치환된 6,5-헤테로-비사이클릭 유도체
RU2331640C2 (ru) 1999-05-21 2008-08-20 Бристол-Маерс Сквибб Ко. Пирролтриазиновые ингибиторы киназ
WO2001014378A1 (fr) 1999-08-23 2001-03-01 Shionogi & Co., Ltd. DERIVES DE PYRROLOTRIAZINE A ACTIVITES INHIBANT sPLA¿2?
US6867300B2 (en) 2000-11-17 2005-03-15 Bristol-Myers Squibb Company Methods for the preparation of pyrrolotriazine compounds useful as kinase inhibitors
US6670357B2 (en) 2000-11-17 2003-12-30 Bristol-Myers Squibb Company Methods of treating p38 kinase-associated conditions and pyrrolotriazine compounds useful as kinase inhibitors
PL366376A1 (en) 2000-11-17 2005-01-24 Bristol-Myers Squibb Company Methods of treating p38 kinase-associated conditions and pyrrolotriazine compounds useful as kinase inhibitors
TW200300350A (en) 2001-11-14 2003-06-01 Bristol Myers Squibb Co C-5 modified indazolylpyrrolotriazines
WO2003090912A1 (en) 2002-04-23 2003-11-06 Bristol-Myers Squibb Company Pyrrolo-triazine aniline compounds useful as kinase inhibitors
ES2318122T3 (es) 2002-04-23 2009-05-01 Bristol-Myers Squibb Company Compuestos de aril cetona pirrolo-triazina utiles como inhibidores de quinasa.
TW200407143A (en) 2002-05-21 2004-05-16 Bristol Myers Squibb Co Pyrrolotriazinone compounds and their use to treat diseases
US6933386B2 (en) 2002-07-19 2005-08-23 Bristol Myers Squibb Company Process for preparing certain pyrrolotriazine compounds
TWI329112B (en) 2002-07-19 2010-08-21 Bristol Myers Squibb Co Novel inhibitors of kinases
WO2004013145A1 (en) 2002-08-02 2004-02-12 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
TW200420565A (en) 2002-12-13 2004-10-16 Bristol Myers Squibb Co C-6 modified indazolylpyrrolotriazines
US7102001B2 (en) 2003-12-12 2006-09-05 Bristol-Myers Squibb Company Process for preparing pyrrolotriazine
MY145634A (en) * 2003-12-29 2012-03-15 Bristol Myers Squibb Co Pyrrolotriazine compounds as kinase inhibitors
US7064203B2 (en) 2003-12-29 2006-06-20 Bristol Myers Squibb Company Di-substituted pyrrolotriazine compounds
US7102002B2 (en) 2004-06-16 2006-09-05 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
US7102003B2 (en) 2004-07-01 2006-09-05 Bristol-Myers Squibb Company Pyrrolotriazine compounds

Also Published As

Publication number Publication date
US20070191375A1 (en) 2007-08-16
ES2372315T3 (es) 2012-01-18
NO20083509L (no) 2008-08-29
CN101384600B (zh) 2012-07-11
WO2007095632A1 (en) 2007-08-23
EP1989207B1 (de) 2011-10-05
CN101384600A (zh) 2009-03-11
US8063208B2 (en) 2011-11-22
JP2009527491A (ja) 2009-07-30
EP1989207A1 (de) 2008-11-12

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