ATE525641T1 - Verfahren zur beurteilung von zielmolekülen - Google Patents

Verfahren zur beurteilung von zielmolekülen

Info

Publication number
ATE525641T1
ATE525641T1 AT09177413T AT09177413T ATE525641T1 AT E525641 T1 ATE525641 T1 AT E525641T1 AT 09177413 T AT09177413 T AT 09177413T AT 09177413 T AT09177413 T AT 09177413T AT E525641 T1 ATE525641 T1 AT E525641T1
Authority
AT
Austria
Prior art keywords
molecule
target molecule
target molecules
therebetween
marker
Prior art date
Application number
AT09177413T
Other languages
English (en)
Inventor
Kenji Arinaga
Ulrich Rant
Erika Pringsheim
Wolfgang Kaiser
Jelena Knezevic
Original Assignee
Fujitsu Ltd
Technical University Of Munich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujitsu Ltd, Technical University Of Munich filed Critical Fujitsu Ltd
Application granted granted Critical
Publication of ATE525641T1 publication Critical patent/ATE525641T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432—Quenching

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT09177413T 2008-11-28 2009-11-27 Verfahren zur beurteilung von zielmolekülen ATE525641T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008303621A JP5352759B2 (ja) 2008-11-28 2008-11-28 ターゲット分子の評価方法

Publications (1)

Publication Number Publication Date
ATE525641T1 true ATE525641T1 (de) 2011-10-15

Family

ID=41721841

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09177413T ATE525641T1 (de) 2008-11-28 2009-11-27 Verfahren zur beurteilung von zielmolekülen

Country Status (4)

Country Link
US (1) US8309365B2 (de)
EP (1) EP2192401B1 (de)
JP (1) JP5352759B2 (de)
AT (1) ATE525641T1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007037341A1 (ja) * 2005-09-29 2007-04-05 Toto Ltd. 光電流を用いた被検物質の特異的検出方法、それに用いられる電極、測定用セルおよび測定装置
EP2434021A1 (de) 2010-09-27 2012-03-28 Technische Universität München Vorrichtung und Verfahren zur Beurteilung der Eigenschaften von Zielmolekülen
JP5562886B2 (ja) * 2011-03-18 2014-07-30 株式会社日立製作所 生体分子計測システム及び生体分子計測方法
GB201301178D0 (en) 2013-01-23 2013-03-06 Dynamic Biosensors Gmbh Method for sequencing a template nucleic acid immobilized on a substrate
DE102013202721A1 (de) * 2013-02-20 2014-08-21 Siemens Aktiengesellschaft Sequenziervorrichtung zum Sequenzieren mindestens eines Nukleinsäureeinzelstrangs und Verfahren zum Sequenzieren mindestens eines Nukleinsäureeinzelstrangs
US20140274747A1 (en) 2013-03-15 2014-09-18 Illumina, Inc. Super resolution imaging
US9193998B2 (en) * 2013-03-15 2015-11-24 Illumina, Inc. Super resolution imaging
US10421997B2 (en) 2014-02-25 2019-09-24 Roche Diagnostics Oeprations, Inc. Molecular dynamic sequencing
CA3170475A1 (en) * 2020-03-02 2021-09-10 Edward H. Sargent Reagentless electrochemical biosensor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4180849B2 (ja) * 2002-06-26 2008-11-12 富士通株式会社 蛋白質検出デバイスおよび蛋白質検出方法
US20060003437A1 (en) * 2002-06-26 2006-01-05 Fujitsu Limited Target detecting device and target capturer, device and method for molecular adsorption or desorption, and device and method for protein detection
JP2004238696A (ja) 2003-02-07 2004-08-26 Kayaba Ind Co Ltd Ｄｌｃコーティング膜
JP4230430B2 (ja) 2003-09-25 2009-02-25 富士通株式会社 被検体評価装置および被検体評価方法
JP4230431B2 (ja) * 2004-08-19 2009-02-25 富士通株式会社 分子の実効サイズ決定法、基板への分子の付着方法および分子検出デバイス
US7169617B2 (en) * 2004-08-19 2007-01-30 Fujitsu Limited Device and method for quantitatively determining an analyte, a method for determining an effective size of a molecule, a method for attaching molecules to a substrate, and a device for detecting molecules

Also Published As

Publication number Publication date
EP2192401B1 (de) 2011-09-21
US8309365B2 (en) 2012-11-13
US20100133121A1 (en) 2010-06-03
JP5352759B2 (ja) 2013-11-27
EP2192401A1 (de) 2010-06-02
JP2010127804A (ja) 2010-06-10

Similar Documents

Publication Publication Date Title
ATE525641T1 (de) Verfahren zur beurteilung von zielmolekülen
DE602004025960D1 (de) Messgerät zur verwendung in einem verfahren zur reduzierung von interferenzen in einem elektrochemischen sensor unter verwendung von zwei unterschiedlichen angelegten potentialen
EP2030139A4 (de) Verfahren und vorrichtung zum abrufen von photogrammetriedaten zur einschätzung der schwere eines aufpralls
DE602004015408D1 (de) Verfahren zur analyse von polymer-populationen
ATE413490T1 (de) Verfahren und vorrichtung zur gezielten applizierung von leistungsfördernden stoffen auf einen kreppzylinder
WO2008138553A8 (en) System and method for analyte measurement using a nonlinear sample response
ATE425266T1 (de) Aptamer-nanopartikelkonjugate und verwendungsverfahren zur detektion von zielanalyten
WO2006117596A8 (en) Nucleic acid probes and nucleic acid analog probes
ATE508360T1 (de) Verfahren, vorrichtungen und computerprogramme zum verifizieren der integrität einer sonde
WO2010046443A3 (en) Methods for detection and diagnosis of a bone or cartilage disorder
ATE536425T1 (de) Mit metabolischem alter verbundene biomarker und verfahren zur verwendung davon
EP3779436A3 (de) Verfahren zur erzeugung von ph/ionischen konzentrationsgradienten in der nähe von elektrodenoberflächen zur modulation von biomolekularen wechselwirkungen
ATE530110T1 (de) Messsystem zur überwachung einer analytkonzentration in vivo und verfahren zur erkennung einer fehlfunktion eines derartigen messsystems
ATE530898T1 (de) Vorrichtung zum messen der wechselstrommagnetisierung von materialien und verfahren zur erkennung von biomolekülen
ATE548467T1 (de) Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände
AT10236U2 (de) Messanordnung und verfahren zur erfassung von messdaten
ATE420211T1 (de) Vorrichtung und verfahren zum nachweis von geladenen makromolekülen
WO2015059487A3 (en) Detection of cleavage activity of an enzyme
EP1877785A4 (de) Verfahren zur messung der glycanniveaus von proteinen
WO2008108873A3 (en) Molecular biosensors for detecting macromolecules and other analytes
DE602005018530D1 (de) Verfahren zum nachweis von mikro-rna-molekülen
MX2010004335A (es) Metodo y sistema para la deteccion de un tipo seleccionado de moleculas en una muestra.
DE602005000485D1 (de) Nukleinsäurenachweisverfahren mittels mehreren Paaren von Donorflurophoren und Quenchemolekülen in derselben Sonde
ATE519116T1 (de) Verfahren zur normierung der konzentration von analyten in einer urinprobe
ATE468535T1 (de) Verwendung von nnmt als marker für lungenkrebs

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties