ATE522537T1 - (e)-n-ä3-ä1-(8-fluor-11h-10-oxa-1-aza-dibenzo-ä , dü-cyclohepten-5-yliden)-propylü-phenylü- methylsulfon-amid als glucocorticoid- rezeptormodulator zur behandlung rheumatoider arthritis - Google Patents
(e)-n-ä3-ä1-(8-fluor-11h-10-oxa-1-aza-dibenzo-ä , dü-cyclohepten-5-yliden)-propylü-phenylü- methylsulfon-amid als glucocorticoid- rezeptormodulator zur behandlung rheumatoider arthritisInfo
- Publication number
- ATE522537T1 ATE522537T1 AT09701170T AT09701170T ATE522537T1 AT E522537 T1 ATE522537 T1 AT E522537T1 AT 09701170 T AT09701170 T AT 09701170T AT 09701170 T AT09701170 T AT 09701170T AT E522537 T1 ATE522537 T1 AT E522537T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- propylü
- phenylü
- methylsulfone
- cyclohepten
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2052008P | 2008-01-11 | 2008-01-11 | |
PCT/US2009/030374 WO2009089312A1 (en) | 2008-01-11 | 2009-01-08 | (e)-n-{3- [1-(8-fluoro-11h-10-oxa-1-aza-dibenzo [a,d] cycl0hepten-5ylidene)-propyl]-phenyl }-methynsulfon amide as glucocorticoid receptor modulator for the treatment of rheumatoid |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE522537T1 true ATE522537T1 (de) | 2011-09-15 |
Family
ID=40456776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09701170T ATE522537T1 (de) | 2008-01-11 | 2009-01-08 | (e)-n-ä3-ä1-(8-fluor-11h-10-oxa-1-aza-dibenzo-ä , dü-cyclohepten-5-yliden)-propylü-phenylü- methylsulfon-amid als glucocorticoid- rezeptormodulator zur behandlung rheumatoider arthritis |
Country Status (13)
Country | Link |
---|---|
US (1) | US8101761B2 (de) |
EP (1) | EP2231676B1 (de) |
JP (1) | JP2011525474A (de) |
KR (1) | KR101237296B1 (de) |
CN (1) | CN101910179B (de) |
AT (1) | ATE522537T1 (de) |
AU (1) | AU2009204155A1 (de) |
BR (1) | BRPI0906945A2 (de) |
CA (1) | CA2711885A1 (de) |
EA (1) | EA017288B1 (de) |
ES (1) | ES2370148T3 (de) |
MX (1) | MX2010007607A (de) |
WO (1) | WO2009089312A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011081173A1 (ja) * | 2009-12-29 | 2011-07-07 | 協和発酵キリン株式会社 | 四環系化合物 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2603713B1 (fr) | 1986-09-10 | 1992-07-24 | Canon Kk | Derive nouveau de 5h-dibenzo(a,d)cycloheptane-(ene)ylidene, son procede de production et support electrophotographique photosensible le contenant |
JPH01161245A (ja) | 1987-12-18 | 1989-06-23 | Canon Inc | 電子写真感光体 |
CA1338625C (en) | 1988-06-09 | 1996-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5093210A (en) | 1989-06-30 | 1992-03-03 | Ricoh Company, Ltd. | Electroluminescent device |
US5378701A (en) | 1991-12-27 | 1995-01-03 | Kyowa Hakko Kogyo | Tricyclic compounds |
US6372779B1 (en) | 1997-12-29 | 2002-04-16 | Ortho Pharmaceutical Corporation | Anti-inflammatory compounds |
CA2361734A1 (en) | 1999-01-26 | 2000-10-12 | Andre Rosowsky | Pharmaceutically active compounds and methods of use thereof |
TW200400816A (en) * | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
ES2308296T3 (es) * | 2003-12-19 | 2008-12-01 | Eli Lilly And Company | Modulares del receptor nuclear de hormonas esteroideas triciclicas. |
EP2043646B1 (de) * | 2006-07-14 | 2012-05-16 | Eli Lilly And Company | (E)-N-{3-(8-Chloro-11H-10-oxa-1-aza- dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-phenyl} -methanesulfonamide als GLUCOCORTICOIDREZEPTORMODULATOR UND VERWENDUNGSVERFAHREN |
-
2009
- 2009-01-08 EP EP09701170A patent/EP2231676B1/de not_active Not-in-force
- 2009-01-08 KR KR1020107015234A patent/KR101237296B1/ko not_active IP Right Cessation
- 2009-01-08 WO PCT/US2009/030374 patent/WO2009089312A1/en active Application Filing
- 2009-01-08 US US12/810,886 patent/US8101761B2/en not_active Expired - Fee Related
- 2009-01-08 CN CN2009801019746A patent/CN101910179B/zh not_active Expired - Fee Related
- 2009-01-08 BR BRPI0906945-3A patent/BRPI0906945A2/pt not_active IP Right Cessation
- 2009-01-08 AU AU2009204155A patent/AU2009204155A1/en not_active Abandoned
- 2009-01-08 MX MX2010007607A patent/MX2010007607A/es active IP Right Grant
- 2009-01-08 AT AT09701170T patent/ATE522537T1/de not_active IP Right Cessation
- 2009-01-08 EA EA201070844A patent/EA017288B1/ru not_active IP Right Cessation
- 2009-01-08 ES ES09701170T patent/ES2370148T3/es active Active
- 2009-01-08 CA CA2711885A patent/CA2711885A1/en not_active Abandoned
- 2009-01-08 JP JP2010542329A patent/JP2011525474A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EA017288B1 (ru) | 2012-11-30 |
US8101761B2 (en) | 2012-01-24 |
CN101910179A (zh) | 2010-12-08 |
KR101237296B1 (ko) | 2013-03-04 |
BRPI0906945A2 (pt) | 2015-07-14 |
AU2009204155A1 (en) | 2009-07-16 |
AU2009204155A8 (en) | 2010-07-08 |
CA2711885A1 (en) | 2009-07-16 |
KR20100090808A (ko) | 2010-08-17 |
WO2009089312A1 (en) | 2009-07-16 |
US20100280062A1 (en) | 2010-11-04 |
EA201070844A1 (ru) | 2011-02-28 |
ES2370148T3 (es) | 2011-12-13 |
EP2231676B1 (de) | 2011-08-31 |
EP2231676A1 (de) | 2010-09-29 |
MX2010007607A (es) | 2010-08-23 |
JP2011525474A (ja) | 2011-09-22 |
CN101910179B (zh) | 2013-06-19 |
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