ATE517980T1 - Verfahren und vorrichtung f r rasche zellenblockeinbettung - Google Patents

Verfahren und vorrichtung f r rasche zellenblockeinbettung

Info

Publication number
ATE517980T1
ATE517980T1 AT03768547T AT03768547T ATE517980T1 AT E517980 T1 ATE517980 T1 AT E517980T1 AT 03768547 T AT03768547 T AT 03768547T AT 03768547 T AT03768547 T AT 03768547T AT E517980 T1 ATE517980 T1 AT E517980T1
Authority
AT
Austria
Prior art keywords
wax
filter
cassette
fragments
disk
Prior art date
Application number
AT03768547T
Other languages
English (en)
Inventor
Andrew Fischer
Original Assignee
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts filed Critical Univ Massachusetts
Application granted granted Critical
Publication of ATE517980T1 publication Critical patent/ATE517980T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36Embedding or analogous mounting of samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877Flow chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • G01N2001/315Basket-type carriers for tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Data Exchanges In Wide-Area Networks (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT03768547T 2002-10-31 2003-10-30 Verfahren und vorrichtung f r rasche zellenblockeinbettung ATE517980T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42276802P 2002-10-31 2002-10-31
PCT/US2003/034467 WO2004041994A1 (en) 2002-10-31 2003-10-30 Rapid cell block embedding method and apparatus

Publications (1)

Publication Number Publication Date
ATE517980T1 true ATE517980T1 (de) 2011-08-15

Family

ID=32312555

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03768547T ATE517980T1 (de) 2002-10-31 2003-10-30 Verfahren und vorrichtung f r rasche zellenblockeinbettung

Country Status (10)

Country Link
US (1) US6913921B2 (de)
EP (2) EP1563055B1 (de)
JP (2) JP4571503B2 (de)
AT (1) ATE517980T1 (de)
AU (1) AU2003291659A1 (de)
CA (1) CA2502580C (de)
DK (1) DK1563055T3 (de)
ES (1) ES2372169T3 (de)
PT (1) PT1563055E (de)
WO (1) WO2004041994A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009390A1 (en) * 1997-08-20 1999-02-25 The University Of Miami A high quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method
US7541161B2 (en) * 2002-10-31 2009-06-02 University Of Massachusetts Method and apparatus for preparing cells for microtome sectioning and archiving nucleic acids and proteins
US20060121597A1 (en) * 2004-11-24 2006-06-08 Rongshan Li Cytoblock preparation system and methods of use
US7769962B2 (en) * 2005-12-12 2010-08-03 Jeda Technologies, Inc. System and method for thread creation and memory management in an object-oriented programming environment
BRPI0709331A2 (pt) 2006-03-20 2011-07-12 Rongshan Li aparelho e método
WO2007137272A2 (en) * 2006-05-22 2007-11-29 10H, Inc. Device and methods for preparing microscopy samples
EP2069750B1 (de) * 2006-08-15 2014-07-02 Cytyc Corporation System für zellenblockeinbettung
US20080044895A1 (en) * 2006-08-17 2008-02-21 Oxyphen Ag Filter support for use with a tissue cassette for collecting and embedding cells
US7666358B2 (en) * 2006-10-20 2010-02-23 Cytyc Corporation Cell block cassette device
BRPI0718425B8 (pt) * 2006-12-12 2021-06-22 Biopath Automation Llc dispositivo de suporte de amostra de tecido histológico
US7906076B2 (en) * 2007-07-02 2011-03-15 University Of Massachusetts Method and apparatus for biopsy sample processing
US8118962B2 (en) * 2007-12-27 2012-02-21 Cytyc Corporation Method and apparatus for spacing cellular matter in a cell block
US8137642B2 (en) * 2008-06-13 2012-03-20 Cytyc Corporation Method and apparatus for calibrating filters during specimen collection
US20100028403A1 (en) * 2008-07-31 2010-02-04 Boston Scientific Scimed, Inc. Medical devices for therapeutic agent delivery
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
PT2556171E (pt) 2010-04-05 2015-12-21 Prognosys Biosciences Inc Ensaios biológicos codificados espacialmente
JP5947794B2 (ja) 2010-08-02 2016-07-06 マイクロスコピー イノベーションズ, エルエルシーMicroscopy Innovations, Llc 顕微鏡用標本作製のための方法及び装置
AU2012243112B2 (en) 2011-04-11 2016-03-24 Rongshan Li Multifunction aspiration biopsy device and methods of use
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
EP2546628A1 (de) * 2011-07-13 2013-01-16 Koninklijke Philips Electronics N.V. Filterhalter für phasenwechselndes Medium
US9217696B2 (en) * 2011-09-29 2015-12-22 The University Of Miami Ultra-rapid diagnostic tissue preparation as an alternative to frozen section
WO2013059526A1 (en) 2011-10-18 2013-04-25 The Trustees Of Columbia University In The City Of New York Medical apparatus and method for collecting biological samples
US9395283B1 (en) 2012-03-14 2016-07-19 Alamak Biosciences Incorporation Company Limited In vitro homogenous cell block, method of making and using
US10197479B1 (en) 2012-03-14 2019-02-05 Alamak Biosciences Incorporation Company Limited In vitro homogenous DNA and RNA cell blocks made using a multi-chambered rotating apparatus
CA2877827A1 (en) 2012-06-27 2014-01-03 Wake Forest University Health Sciences Cell pathology tubes and associated cell processing methods
USRE50065E1 (en) 2012-10-17 2024-07-30 10X Genomics Sweden Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
CN110074820A (zh) 2012-11-20 2019-08-02 纽约哥伦比亚大学董事会 医疗设备以及用于收集生物样本的方法
DK3013984T3 (da) 2013-06-25 2023-06-06 Prognosys Biosciences Inc Metode til bestemmelse af spatiale mønstre i biologiske targets i en prøve
KR101643403B1 (ko) * 2013-09-09 2016-07-28 국립암센터 파라핀블록 제조용 혈중 세포 응집제 및 이를 이용한 파라핀블록 제조방법
WO2015034178A1 (ko) * 2013-09-09 2015-03-12 국립암센터 파라핀블록 제조용 혈중 세포 응집제 및 이를 이용한 파라핀블록 제조방법
US11109846B2 (en) * 2014-02-14 2021-09-07 Memorial Sloan-Kettering Cancer Center System and method for providing assessment of tumor and other biological components contained in tissue biopsy samples
CN105675373B (zh) * 2014-04-23 2018-11-09 杭州电子科技大学 具有快速定位功能的细胞蜡块制备装置
CN105890943B (zh) * 2014-04-23 2019-01-25 杭州电子科技大学 具有自动检测功能的细胞蜡块制备装置
WO2016010858A1 (en) * 2014-07-14 2016-01-21 Musc Foundation For Research Development Method and apparatus for cell block preparation of cytology specimens
CN104297041B (zh) * 2014-10-24 2017-02-15 沈阳安真医疗器械有限公司 多功能组织脱水定位包埋全自动包埋机及其使用方法
EP3214166A4 (de) * 2014-10-31 2018-07-04 National University Corporation Tokyo University of Agriculture and Technology Zellisolierverfahren und zelleinfangfilter
FI3901281T3 (fi) 2015-04-10 2023-01-31 Biologisten näytteiden spatiaalisesti eroteltu moninkertainen nukleiinihappoanalyysi
CN104777029B (zh) * 2015-04-21 2017-10-13 沈阳安真医疗器械有限公司 生物组织包埋单元、模板、脱水包埋两用机及使用方法
USD852375S1 (en) 2017-10-25 2019-06-25 Wake Forest University Health Sciences Cell collection and centrifuge tube assembly
CN107907396B (zh) * 2017-11-07 2020-11-10 山西大学 一种生物组织自动免疫组化染色系统
EP3705870B1 (de) * 2019-03-07 2022-04-27 Siemens Healthcare GmbH Vorrichtung, verwendung und verfahren zur präparation in der histopathologie
EP4414459A3 (de) 2020-05-22 2024-09-18 10X Genomics, Inc. Simultane räumlich-zeitliche messung der genexpression und der zellaktivität
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
WO2022178267A2 (en) 2021-02-19 2022-08-25 10X Genomics, Inc. Modular assay support devices
CN114345433B (zh) * 2022-01-21 2023-03-07 中国科学技术大学 一种高温恒温移液与过滤装置及其方法
EP4261522A1 (de) * 2022-04-11 2023-10-18 Array Science, LLC Verfahren zur herstellung von kernen mit hoher ausbeute zur verwendung in einem mikroarrayblock

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2923669A (en) 1954-11-22 1960-02-02 Millipore Filter Corp Method of bacterial analysis
BE627822A (de) * 1962-02-01
DE2928790A1 (de) * 1979-07-17 1981-02-12 Sartorius Gmbh Verfahren und vorrichtung zur gewinnung und auswertung von zellpraeparaten aus fluessigen medien, insbesondere aus urin u.a. koerperfluessigkeiten fuer die pruefung auf tumorverdacht
ATE19155T1 (de) * 1981-10-20 1986-04-15 Shandon Southern Prod Geraet zur behandlung von gewebe.
US4569647A (en) 1983-09-16 1986-02-11 Pelam, Inc. Apparatus for preparing and embedding tissue samples for histological examination
US4557903A (en) 1983-09-16 1985-12-10 Pelam, Inc. Apparatus for preparing and embedding tissue samples for histological examination
US4656047A (en) 1986-03-06 1987-04-07 Kok Lanbrecht P Rapid method for cell block preparation
GB2189596B (en) * 1986-04-16 1990-08-01 Pa Consulting Services Methods of and apparatus for preparing tissue specimens
GB8915759D0 (en) 1989-07-10 1989-08-31 Shandon Scient Ltd Cell block preparation
JP2923669B2 (ja) * 1990-03-28 1999-07-26 株式会社資生堂 溶剤系ネールエナメル
US5266495A (en) 1990-03-02 1993-11-30 Cytyc Corporation Method and apparatus for controlled instrumentation of particles with a filter device
US5080869A (en) 1990-08-14 1992-01-14 Mccormick James B Apparatus and method for preparing tissue samples for histological examination
US5269671A (en) 1992-02-11 1993-12-14 Mccormick James B Apparatus for embedding tissue samples
US5354370A (en) 1992-04-15 1994-10-11 Hacker Industries, Inc. Tissue processor
GB9215733D0 (en) * 1992-07-24 1992-09-09 British Tech Group Method of and apparatus for determining a property of a sample
US5532168A (en) * 1994-08-18 1996-07-02 Marantz; Calvin Tissue biopsy specimen strainer and method
US5665398A (en) 1995-11-20 1997-09-09 Mccormick; James B. Apparatus for embedding tissue samples
US5817032A (en) 1996-05-14 1998-10-06 Biopath Automation Llc. Means and method for harvesting and handling tissue samples for biopsy analysis
WO2000019897A1 (en) * 1998-10-05 2000-04-13 Williamson Warren N Apparatus and method for harvesting and handling tissue samples for biopsy analysis
RU2150097C1 (ru) 1997-03-17 2000-05-27 Извозчиков Илья Борисович Устройство для обработки и пропитки гистологических образцов
WO1999009390A1 (en) 1997-08-20 1999-02-25 The University Of Miami A high quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method
US5928934A (en) 1998-04-14 1999-07-27 Mccormick; James B. Apparatus and method for preparing small tissue samples for histological examination
US6372512B1 (en) * 1998-09-16 2002-04-16 Resolution Sciences Corporation Combined en bloc staining and embedding process
JP2000146782A (ja) * 1998-11-12 2000-05-26 Yoshio Kawai 自動固定標本作製装置および方法
US6395234B1 (en) 2000-02-08 2002-05-28 Triangle Biomedical Sciences, Inc. Sample cassette having utility for histological processing of tissue samples
JP2002286601A (ja) * 2001-03-28 2002-10-03 Teiji Takezaki 生検試料の収納装置と方法
JP4695286B2 (ja) * 2001-04-20 2011-06-08 サクラ精機株式会社 包埋装置及びその温度制御方法
JP4604964B2 (ja) * 2005-10-31 2011-01-05 オムロン株式会社 送受信装置、変調集積回路およびrfidリーダライタ

Also Published As

Publication number Publication date
AU2003291659A1 (en) 2004-06-07
EP1563055B1 (de) 2011-07-27
JP2006504432A (ja) 2006-02-09
DK1563055T3 (da) 2011-11-21
EP1563055A4 (de) 2009-06-17
JP4571503B2 (ja) 2010-10-27
US20040121456A1 (en) 2004-06-24
ES2372169T3 (es) 2012-01-16
EP2237013A1 (de) 2010-10-06
CA2502580C (en) 2013-09-10
EP1563055A1 (de) 2005-08-17
JP2010266458A (ja) 2010-11-25
WO2004041994A1 (en) 2004-05-21
PT1563055E (pt) 2011-11-09
CA2502580A1 (en) 2004-05-21
US6913921B2 (en) 2005-07-05
EP2237013B1 (de) 2012-06-06
JP5204810B2 (ja) 2013-06-05

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