ATE516270T1 - Neue derivate von psammaplin a, verfahren zu ihrer synthese und ihre verwendung für die vorbeugung oder behandlung von krebs - Google Patents

Neue derivate von psammaplin a, verfahren zu ihrer synthese und ihre verwendung für die vorbeugung oder behandlung von krebs

Info

Publication number
ATE516270T1
ATE516270T1 AT08763019T AT08763019T ATE516270T1 AT E516270 T1 ATE516270 T1 AT E516270T1 AT 08763019 T AT08763019 T AT 08763019T AT 08763019 T AT08763019 T AT 08763019T AT E516270 T1 ATE516270 T1 AT E516270T1
Authority
AT
Austria
Prior art keywords
psammaplin
cancer
synthesis
prevention
treatment
Prior art date
Application number
AT08763019T
Other languages
English (en)
Inventor
Hinrich Gronemeyer
Lucia Altucci
Lera Angel De
Hendrik Gerard Stunnenberg
Original Assignee
Centre Nat Rech Scient
Seconda Uni Degli Studi Di Napoli
Univ Vigo
Inst Nat Sante Rech Med
Univ Strasbourg
Radbound University Nijmegen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Seconda Uni Degli Studi Di Napoli, Univ Vigo, Inst Nat Sante Rech Med, Univ Strasbourg, Radbound University Nijmegen filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE516270T1 publication Critical patent/ATE516270T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
AT08763019T 2007-02-28 2008-02-28 Neue derivate von psammaplin a, verfahren zu ihrer synthese und ihre verwendung für die vorbeugung oder behandlung von krebs ATE516270T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07290253A EP1964835A1 (de) 2007-02-28 2007-02-28 Derivate von Psammaplin A, Verfahren zu ihrer Synthese und ihre Verwendung für die Vorbeugung oder Behandlung von Krebs
PCT/IB2008/001887 WO2008125988A1 (en) 2007-02-28 2008-02-28 Novel derivatives of psammaplin a, a method for their synthesis and their use for the prevention or treatment of cancer

Publications (1)

Publication Number Publication Date
ATE516270T1 true ATE516270T1 (de) 2011-07-15

Family

ID=37998389

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08763019T ATE516270T1 (de) 2007-02-28 2008-02-28 Neue derivate von psammaplin a, verfahren zu ihrer synthese und ihre verwendung für die vorbeugung oder behandlung von krebs

Country Status (10)

Country Link
US (1) US8338473B2 (de)
EP (2) EP1964835A1 (de)
JP (1) JP5329439B2 (de)
CN (1) CN101720315B (de)
AT (1) ATE516270T1 (de)
AU (1) AU2008238924B2 (de)
CA (1) CA2678833A1 (de)
ES (1) ES2372717T3 (de)
IL (1) IL200410A (de)
WO (1) WO2008125988A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011084623A1 (en) 2009-12-16 2011-07-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method of sensitizing cancer cells to the cytotoxic effects of death receptor ligands in cancer treatment
CN102503869B (zh) * 2011-10-19 2014-05-21 沈阳药科大学 2-羟亚胺苯丙酰胺基乙二硫基类衍生物及其应用
EP2730558A1 (de) * 2012-11-08 2014-05-14 Ikerchem, S.L. Indolderivate, pharmazeutische Zusammensetzungen mit solchen Indolen und deren Verwendung als DNA-Methylierungsmodulatoren
EP3207932A1 (de) 2016-02-19 2017-08-23 Universität Stuttgart Dna-methyltransferaseninhibitoren für rett-syndromtherapie
US20210299069A1 (en) * 2016-08-26 2021-09-30 Idogen Ab Psammaplin a for modulating ido expression
CN107739316B (zh) * 2017-11-14 2020-07-14 中国医科大学 一种溴代酪氨酸生物碱类化合物及其制备方法和用途
CN111548286B (zh) * 2020-05-13 2022-09-06 沈阳药科大学 一种具有hdac3抑制活性的psa衍生物及其应用
CN114890932A (zh) * 2022-06-24 2022-08-12 大理大学 一种吲哚生物碱Luteoride A的首次全合成工艺
CN115028567A (zh) * 2022-06-24 2022-09-09 大理大学 一种吲哚生物碱Luteoride B的合成工艺
CN115925675A (zh) * 2022-11-10 2023-04-07 中国海洋大学 一种Psammaplin A类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0501378T3 (da) * 1991-02-28 1995-03-20 Merrell Dow Pharma NMDA-antagonister
JPH0725858A (ja) * 1993-07-13 1995-01-27 Otsuka Pharmaceut Co Ltd ピペラジン誘導体
DE19814838C2 (de) * 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
WO2007025169A2 (en) * 2005-08-25 2007-03-01 Emory University Hif inhibitors

Also Published As

Publication number Publication date
ES2372717T3 (es) 2012-01-25
CN101720315B (zh) 2012-07-18
CA2678833A1 (en) 2008-10-23
AU2008238924A1 (en) 2008-10-23
EP2137147A1 (de) 2009-12-30
IL200410A0 (en) 2010-05-31
JP2010520192A (ja) 2010-06-10
US20100120885A1 (en) 2010-05-13
EP2137147B1 (de) 2011-07-13
US8338473B2 (en) 2012-12-25
AU2008238924B2 (en) 2013-06-27
WO2008125988A1 (en) 2008-10-23
CN101720315A (zh) 2010-06-02
JP5329439B2 (ja) 2013-10-30
IL200410A (en) 2013-10-31
EP1964835A1 (de) 2008-09-03

Similar Documents

Publication Publication Date Title
ATE516270T1 (de) Neue derivate von psammaplin a, verfahren zu ihrer synthese und ihre verwendung für die vorbeugung oder behandlung von krebs
BRPI0409198A (pt) derivados quinolin-2-ona para o tratamento de doenças de vias aéreas
DK1853602T3 (da) Kemiske forbindelser
DK1853588T3 (da) Kemiske forbindelser
NO20091661L (no) Anvendelse av pegylert IL-10 for a behandle kreft
WO2009126863A3 (en) Pyridyl inhibitors of hedgehog signalling
EA200700851A1 (ru) Получение и применение бифенил-4-илкарбониламинокислотных производных для лечения ожирения
TW200716606A (en) Chemical compounds
TW200800963A (en) Chemical compounds
ATE547102T1 (de) Carbolin-derivate zur behandlung von krebs
ATE556074T1 (de) Neue imidazoä1,5-aüpyridinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese enthalten
ATE538652T1 (de) Synergistische pharmazeutische kombination für die behandlung von krebs
TNSN08370A1 (en) Tetrahydropyridothienopyrimidine compounds and methods of use thereof
BRPI0908635A8 (pt) composto, composição farmacêutica e método de tratamento de câncer
NZ597857A (en) Method and composition for treating mucosal disorders
MA32943B1 (fr) Piperidine spiro pyrrolidione et piperidinone substituees, leur preparation et leur utilisation therapeutique
WO2010075280A3 (en) Coumarin-based compounds for the treatment of alzheimer's disease and cancer
MX2010003269A (es) Derivados de pirrolotriazina utiles para tratar cancer a traves de la inhibicion de la aurora quinasa.
ATE521609T1 (de) Aminothiazolylpyrimidinderivate und ihre verwendung bei der behandlung von krebs
EA201070543A1 (ru) Новые 4-(тетразол-5-ил) хиназолиновые производные в качестве противораковых средств
MX2009013205A (es) Derivados de pirazoloquinolina urea terapeuticos.
MX2010000956A (es) Derivados de isoftalamida que inhiben actividad de beta-secretasa.
WO2010072770A3 (en) Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering
CY1110027T1 (el) Συνδυασμος ενωσεων πυριμιδυλαμινοβενζαμιδης και ιματινιβης για τη θεραπεια ή την προληψη των νεοπλασματικων ασθενειων
ATE518839T1 (de) Azoloarin derivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties