ATE509097T1 - Gewinnung von rekombinantem menschlichem parainfluenzavirus typ 1 (hpivi) aus cdna - Google Patents
Gewinnung von rekombinantem menschlichem parainfluenzavirus typ 1 (hpivi) aus cdnaInfo
- Publication number
- ATE509097T1 ATE509097T1 AT02799195T AT02799195T ATE509097T1 AT E509097 T1 ATE509097 T1 AT E509097T1 AT 02799195 T AT02799195 T AT 02799195T AT 02799195 T AT02799195 T AT 02799195T AT E509097 T1 ATE509097 T1 AT E509097T1
- Authority
- AT
- Austria
- Prior art keywords
- hpivi
- recombinant human
- piv
- cdna
- recombinant
- Prior art date
Links
- 241000726041 Human respirovirus 1 Species 0.000 title 2
- 238000000917 particle-image velocimetry Methods 0.000 abstract 4
- 241000700605 Viruses Species 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 244000052769 pathogen Species 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 208000002606 Paramyxoviridae Infections Diseases 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18641—Use of virus, viral particle or viral elements as a vector
- C12N2760/18643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18661—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33196101P | 2001-11-21 | 2001-11-21 | |
| PCT/US2002/037688 WO2003043587A2 (en) | 2001-11-21 | 2002-11-21 | Recovery of recombinant human parainfluenza virus type 1 (hpivi) from cdna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE509097T1 true ATE509097T1 (de) | 2011-05-15 |
Family
ID=23296092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02799195T ATE509097T1 (de) | 2001-11-21 | 2002-11-21 | Gewinnung von rekombinantem menschlichem parainfluenzavirus typ 1 (hpivi) aus cdna |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7704509B2 (de) |
| EP (2) | EP2100955A3 (de) |
| AT (1) | ATE509097T1 (de) |
| AU (2) | AU2002364121C1 (de) |
| CA (1) | CA2467958A1 (de) |
| WO (1) | WO2003043587A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050287540A1 (en) * | 1995-09-27 | 2005-12-29 | Murphy Brian R | Production of attenuated negative stranded RNA virus vaccines from cloned nucleotide sequences |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| NZ527221A (en) | 2001-01-19 | 2006-09-29 | Vironovative B | A negative-sense single stranded RNA virus causing respiratory tract illness in susceptible mammals |
| JP4553588B2 (ja) | 2002-02-21 | 2010-09-29 | メディミューン，エルエルシー | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
| AU2003270824B2 (en) * | 2002-09-18 | 2009-02-19 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Recovery of recombinant human parainfluenza virus type 2 (HPIV2) from cDNA and use of recombinant HPIV2 in immunogenic compositions and as vectors to elicit immune responses against PIV and other human pathogens |
| JP2007525178A (ja) | 2003-04-25 | 2007-09-06 | メッドイミューン バクシーンズ，インコーポレイティド | メタニューモウイルス株、そのワクチン製剤における用途、抗原性配列の発現のためのベクターとしての用途、並びにウイルス増殖方法 |
| JP2006524511A (ja) * | 2003-04-25 | 2006-11-02 | メッドイミューン バクシーンズ，インコーポレイティド | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
| JP4976376B2 (ja) * | 2005-04-08 | 2012-07-18 | メディミューン，エルエルシー | 哺乳動物メタニューモウイルスに対する抗体 |
| US20070092871A1 (en) * | 2005-10-20 | 2007-04-26 | Combimatrix Corporation | Microarray for pathogen identification |
| US20100330120A1 (en) * | 2007-05-08 | 2010-12-30 | Collins Peter L | Human parainfluenza viruses having separated p and c genes |
| EP2069485A4 (de) * | 2007-07-13 | 2011-05-25 | Medimmune Llc | Zubereitung von negativstrang-rna-viren mittels elektroporation |
| GB0719818D0 (en) * | 2007-10-11 | 2007-11-21 | Asterion Ltd | Growth hormone fusion polypeptides |
| US20090186050A1 (en) * | 2007-11-16 | 2009-07-23 | Fouchier Ron A M | Live attenuated metapneumovirus strains and their use in vaccine formulations and chimeric metapneumovirus strains |
| WO2010003032A2 (en) * | 2008-07-01 | 2010-01-07 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health A | Recombinant human parainfluenza type 1 viruses (hpiv1s) containing mutations in or deletion of the c protein are attenuated in african green monkeys and in ciliated human airway epithelial cells and are potential vaccine candidates for hpiv1 |
| DK2702159T3 (en) | 2011-04-28 | 2018-11-19 | St Jude Childrens Res Hospital | MODIFIED SENDAI VIRUS VACCINE AND IMAGE VECTOR |
| JP7020917B2 (ja) | 2015-01-20 | 2022-02-16 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | キメラｒｓｖ／ｂｐｉｖ３ ｆタンパクを発現する組換えヒト／ウシパラインフルエンザウイルス３（ｂ／ｈｐｉｖ３）およびその使用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US708395A (en) | 1901-04-15 | 1902-09-02 | Oscar Peterson | Device for digging ditches. |
| US2177396A (en) | 1936-04-18 | 1939-10-24 | Borden Co | Milk bottle |
| DE3224404A1 (de) | 1982-06-30 | 1984-01-05 | LuK Lamellen und Kupplungsbau GmbH, 7580 Bühl | Reibungskupplung sowie verfahren zu deren montage |
| US4614197A (en) | 1984-10-15 | 1986-09-30 | Deere & Company | Chaff spreading arrangement for a combine |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4763497A (en) | 1986-09-03 | 1988-08-16 | Clover Co., Ltd. | Lock device for double sliding doors |
| US5938597A (en) | 1995-05-04 | 1999-08-17 | Stratbucker; Robert A. | Electrocardiograph bioelectric interface system and method of use |
| DE69510207T3 (de) | 1995-08-09 | 2007-02-15 | Schweiz. Serum- & Impfinstitut Bern | Verfahren zur Herstellung von infektiösen minussträngigen RNA-Viren |
| US6699476B1 (en) | 1996-07-15 | 2004-03-02 | Peter L. Collins | Production of recombinant respiratory syncytial viruses expressing immune modulatory molecules |
| EP2112220A3 (de) | 1996-07-15 | 2010-01-06 | The Government of the United States of America, as represented by The Department of Health and Human Services | Herstellung abgeschwächter Impfstoffe gegen das respiratorische Synzytialvirus aus geklonten Nukleotidsequenzen |
| AU7797798A (en) | 1997-05-23 | 1998-12-11 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Production of attenuated parainfluenza virus vaccines from cloned nucleotide sequences |
| US6410023B1 (en) | 1997-05-23 | 2002-06-25 | United States Of America | Recombinant parainfluenza virus vaccines attenuated by deletion or ablation of a non-essential gene |
| CA2378661A1 (en) | 1999-07-09 | 2001-01-18 | Alexander C. Schmidt | Attenuated human-bovine chimeric parainfluenza virus (piv) vaccines |
| MXPA01008108A (es) | 1999-12-10 | 2004-11-12 | Health | Uso de virus de parainfluenza recombinante (pivs) como vectores para la proteccioncontra la infeccion y enfermedad provocadas por piv y otros patogenos humanos. |
| US8379398B2 (en) | 2011-03-23 | 2013-02-19 | Phoenix Contact Development & Manufacturing, Inc. | DIN rail mountable base for process fieldbus redundant power conditioner |
-
2002
- 2002-11-21 WO PCT/US2002/037688 patent/WO2003043587A2/en active Search and Examination
- 2002-11-21 US US10/302,547 patent/US7704509B2/en not_active Expired - Lifetime
- 2002-11-21 AU AU2002364121A patent/AU2002364121C1/en not_active Ceased
- 2002-11-21 EP EP09162824A patent/EP2100955A3/de not_active Withdrawn
- 2002-11-21 CA CA002467958A patent/CA2467958A1/en not_active Abandoned
- 2002-11-21 AT AT02799195T patent/ATE509097T1/de not_active IP Right Cessation
- 2002-11-21 EP EP02799195A patent/EP1456398B1/de not_active Expired - Lifetime
-
2009
- 2009-06-12 AU AU2009202359A patent/AU2009202359A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1456398B1 (de) | 2011-05-11 |
| EP1456398A4 (de) | 2006-09-27 |
| WO2003043587A3 (en) | 2004-04-22 |
| CA2467958A1 (en) | 2003-05-30 |
| US7704509B2 (en) | 2010-04-27 |
| AU2002364121B2 (en) | 2009-03-12 |
| EP1456398A2 (de) | 2004-09-15 |
| AU2002364121C1 (en) | 2010-02-18 |
| WO2003043587A9 (en) | 2011-06-09 |
| EP2100955A2 (de) | 2009-09-16 |
| AU2009202359A1 (en) | 2009-07-02 |
| US20040142448A1 (en) | 2004-07-22 |
| WO2003043587A2 (en) | 2003-05-30 |
| EP2100955A3 (de) | 2009-12-02 |
| AU2002364121A1 (en) | 2003-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |