ATE504304T1 - Medizinisches mittel zur verhinderung des fortschreitens apoptotischer und kupierender nekrotischer veränderungen in den organismusgeweben - Google Patents

Medizinisches mittel zur verhinderung des fortschreitens apoptotischer und kupierender nekrotischer veränderungen in den organismusgeweben

Info

Publication number
ATE504304T1
ATE504304T1 AT06747757T AT06747757T ATE504304T1 AT E504304 T1 ATE504304 T1 AT E504304T1 AT 06747757 T AT06747757 T AT 06747757T AT 06747757 T AT06747757 T AT 06747757T AT E504304 T1 ATE504304 T1 AT E504304T1
Authority
AT
Austria
Prior art keywords
derivative
apoptotic
purine
progression
preventing
Prior art date
Application number
AT06747757T
Other languages
English (en)
Inventor
Galina Victorovna Sukoyan
Tengiz Givievich Kharebava
Original Assignee
Obschestvo S Ogranichennoi Otvetstvennostyu N Proizv Kompania Sfarmasofts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Obschestvo S Ogranichennoi Otvetstvennostyu N Proizv Kompania Sfarmasofts filed Critical Obschestvo S Ogranichennoi Otvetstvennostyu N Proizv Kompania Sfarmasofts
Application granted granted Critical
Publication of ATE504304T1 publication Critical patent/ATE504304T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06747757T 2005-04-28 2006-04-19 Medizinisches mittel zur verhinderung des fortschreitens apoptotischer und kupierender nekrotischer veränderungen in den organismusgeweben ATE504304T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2005112851/15A RU2311180C2 (ru) 2005-04-28 2005-04-28 Средство для предотвращения прогрессирования апоптотических и купирования некротических изменений в тканях организма
PCT/RU2006/000198 WO2006115436A1 (fr) 2005-04-28 2006-04-19 Medicament destine a la prevention de la progression de changements apoptotiques et a l'interruption de changements necrotiques dans les tissus du corps

Publications (1)

Publication Number Publication Date
ATE504304T1 true ATE504304T1 (de) 2011-04-15

Family

ID=37214997

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06747757T ATE504304T1 (de) 2005-04-28 2006-04-19 Medizinisches mittel zur verhinderung des fortschreitens apoptotischer und kupierender nekrotischer veränderungen in den organismusgeweben

Country Status (9)

Country Link
EP (1) EP1878431B1 (de)
AT (1) ATE504304T1 (de)
DE (1) DE602006021167D1 (de)
DK (1) DK1878431T3 (de)
EA (1) EA014753B1 (de)
GE (1) GEP20104911B (de)
PT (1) PT1878431E (de)
RU (1) RU2311180C2 (de)
WO (1) WO2006115436A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2671200C2 (ru) * 2015-12-07 2018-10-30 Закрытое Акционерное Общество "Фармфирма "Сотекс" Способ получения 6-метил-2-этилпиридин-3-ол соли (2S)-2-ацетаминопентандиовой кислоты
RU2664453C1 (ru) * 2017-11-24 2018-08-17 федеральное государственное бюджетное образовательное учреждение высшего образования "Тверской государственный медицинский университет" Министерства здравоохранения Российской Федерации Производное 3-гидроксипиридина с анксиолитической и ноотропной активностью

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU98104073A (ru) * 1995-09-14 2000-01-27 Эл-Экс-Ар Биотекнолоджи Инк. Композиция, обладающая антиапоптотической активностью, содержащая смесь фосфолипидов
US5668114A (en) * 1996-05-08 1997-09-16 Birkmayer Pharmaceuticals NADH and NADPH pharmaceuticals for treating hypertension
AR016551A1 (es) * 1997-07-30 2001-07-25 Smithkline Beecham Corp Derivados de 2-oxindol, composiciones farmaceuticas que los comprenden y el uso de los mismos para la manufactura de medicamentos
US6514983B1 (en) * 1997-09-03 2003-02-04 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
RU2168993C1 (ru) * 2000-05-11 2001-06-20 Михин Вадим Петрович Средство для лечения нестабильной стенокардии и острого инфаркта миокарда
RU2205640C1 (ru) * 2002-04-09 2003-06-10 Общество с ограниченной ответственностью "Экофарминвест" Стабильный фармацевтический состав, содержащий мексидол
AU2003264195A1 (en) * 2002-09-03 2004-03-29 Neurological Technologies Inc. Use of guanosine or inosine as anti-apoptotic agents in the treatment of i. a. neurodegenerative diseases or injuries at the nervous system
EP1638579A2 (de) * 2003-07-02 2006-03-29 Emory University Zusammensetzungen und verfahren zur verwendung eines protease-inhibitors und von adenosin zur prävention von organischämie und reperfusionsschäden
RU2250210C1 (ru) * 2003-07-25 2005-04-20 Институт Проблем Химической Физики Российской Академии Наук (Ипхф Ран) Нитроксисукцинат 2,4,6-триметил-3-оксипиридина и способ его получения

Also Published As

Publication number Publication date
EA200702356A1 (ru) 2008-04-28
EP1878431B1 (de) 2011-04-06
EP1878431A1 (de) 2008-01-16
PT1878431E (pt) 2011-06-30
EP1878431A4 (de) 2009-05-27
GEP20104911B (en) 2010-03-10
RU2311180C2 (ru) 2007-11-27
RU2005112851A (ru) 2006-11-10
DE602006021167D1 (de) 2011-05-19
EA014753B1 (ru) 2011-02-28
WO2006115436A1 (fr) 2006-11-02
DK1878431T3 (da) 2011-06-06

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