ATE503472T1 - Nateglinide-tablettenzubereitungen - Google Patents
Nateglinide-tablettenzubereitungenInfo
- Publication number
- ATE503472T1 ATE503472T1 AT05014497T AT05014497T ATE503472T1 AT E503472 T1 ATE503472 T1 AT E503472T1 AT 05014497 T AT05014497 T AT 05014497T AT 05014497 T AT05014497 T AT 05014497T AT E503472 T1 ATE503472 T1 AT E503472T1
- Authority
- AT
- Austria
- Prior art keywords
- meals
- tablet preparations
- carboxymethyl cellulose
- tablet composition
- nateglinide tablet
- Prior art date
Links
- OELFLUMRDSZNSF-BRWVUGGUSA-N nateglinide Chemical compound C1C[C@@H](C(C)C)CC[C@@H]1C(=O)N[C@@H](C(O)=O)CC1=CC=CC=C1 OELFLUMRDSZNSF-BRWVUGGUSA-N 0.000 title abstract 2
- 229960000698 nateglinide Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 2
- 235000012054 meals Nutrition 0.000 abstract 2
- 239000007916 tablet composition Substances 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31854196 | 1996-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE503472T1 true ATE503472T1 (de) | 2011-04-15 |
Family
ID=18100283
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97912459T ATE322260T1 (de) | 1996-11-15 | 1997-11-14 | Nateglinide zubereitung in tablettenform |
| AT05014497T ATE503472T1 (de) | 1996-11-15 | 1997-11-14 | Nateglinide-tablettenzubereitungen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97912459T ATE322260T1 (de) | 1996-11-15 | 1997-11-14 | Nateglinide zubereitung in tablettenform |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US6143323A (de) |
| EP (3) | EP2277517A1 (de) |
| JP (1) | JP4171091B2 (de) |
| KR (1) | KR100343062B1 (de) |
| CN (1) | CN1245158C (de) |
| AT (2) | ATE322260T1 (de) |
| AU (1) | AU718350B2 (de) |
| CA (1) | CA2271865C (de) |
| DE (2) | DE69735644T2 (de) |
| DK (1) | DK1586314T3 (de) |
| ES (2) | ES2257772T3 (de) |
| PT (2) | PT965339E (de) |
| TW (1) | TW492878B (de) |
| WO (1) | WO1998022105A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100343062B1 (ko) * | 1996-11-15 | 2002-07-02 | 에가시라 구니오 | 정제 조성물 |
| EP2263660B1 (de) | 1998-05-18 | 2017-09-27 | Takeda Pharmaceutical Company Limited | Im Munde zerfallende Tablette |
| DE69942777D1 (de) * | 1998-07-28 | 2010-10-28 | Takeda Pharmaceutical | Leicht zerfallende feste Zubereitung |
| JP2000119160A (ja) * | 1998-10-06 | 2000-04-25 | Kanebo Ltd | 皮膚化粧料 |
| CO5200844A1 (es) * | 1999-09-17 | 2002-09-27 | Novartis Ag | Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes |
| US6559188B1 (en) | 1999-09-17 | 2003-05-06 | Novartis Ag | Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes |
| US6878749B2 (en) | 1999-09-17 | 2005-04-12 | Novartis Ag | Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes |
| ES2248159T3 (es) | 1999-12-28 | 2006-03-16 | Ajinomoto Co., Inc. | Preparaciones orales para diabetes. |
| EP1283054A4 (de) * | 2000-03-17 | 2006-04-12 | Ajinomoto Kk | Medikamente zur behandlung von komplikationen des diabetes und neuropathien, und verwendung davon |
| WO2002032854A1 (en) * | 2000-10-18 | 2002-04-25 | Ajinomoto Co.,Inc. | Process for producing nateglinide crystal |
| ATE373635T1 (de) | 2000-10-18 | 2007-10-15 | Ajinomoto Kk | Verfahren zur herstellung von acylphenylalaninen |
| BR0114846A (pt) | 2000-10-24 | 2004-02-25 | Ajinomoto Kk | Método para produzir cristais de tipo b de nateglinida substancialmente livres de cristais de tipo h |
| PT1334721E (pt) * | 2000-10-24 | 2009-06-01 | Ajinomoto Kk | Preparações de fármacos hidrofílicos contendo nateglinida |
| AU2001295999A1 (en) * | 2000-10-24 | 2002-05-06 | Ajinomoto Co., Inc. | Nateglinide-containing preparations |
| US20080058424A1 (en) * | 2002-05-23 | 2008-03-06 | Cephalon, Inc. | Novel pharmaceutical formulations of modafinil |
| JP2003252749A (ja) * | 2002-03-04 | 2003-09-10 | Shin Etsu Chem Co Ltd | 外用基剤 |
| US6830759B2 (en) | 2002-06-28 | 2004-12-14 | Ajinomoto Co., Inc. | Antidiabetic preparation for oral administration |
| CN1247194C (zh) * | 2002-08-27 | 2006-03-29 | 石药集团中奇制药技术(石家庄)有限公司 | 一种那格列奈包合物 |
| US20040116532A1 (en) * | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
| US20050065183A1 (en) * | 2003-07-31 | 2005-03-24 | Indranil Nandi | Fexofenadine composition and process for preparing |
| WO2005013964A1 (ja) * | 2003-08-08 | 2005-02-17 | Ajinomoto Co., Inc. | ナテグリニド含有製剤 |
| WO2005016315A1 (en) * | 2003-08-14 | 2005-02-24 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of nateglinide and a high amount of a water-soluble filler |
| WO2005094812A1 (ja) * | 2004-04-01 | 2005-10-13 | Ajinomoto Co., Inc. | ナテグリニド含有製剤 |
| WO2005117840A1 (en) * | 2004-05-31 | 2005-12-15 | Ranbaxy Laboratories Limited | Stable pharmaceutical compositions comprising pulverized granules of nateglinide of form b |
| WO2006013444A1 (en) * | 2004-07-28 | 2006-02-09 | Ranbaxy Laboratories Limited | Preparations of stable pharmaceutical compositions of nateglinide and processes for their preparation |
| JP2008509144A (ja) * | 2004-08-04 | 2008-03-27 | アルザ・コーポレーシヨン | 上昇するゼロ次放出パターンを示す持続薬剤放出組成物、そのような組成物を製造する方法 |
| KR20070058540A (ko) * | 2004-10-01 | 2007-06-08 | 니폰 조키 세야쿠 가부시키가이샤 | 고형 의약제제 |
| US7276198B2 (en) * | 2004-12-28 | 2007-10-02 | The Goodyear Tire & Rubber Company | Method and mold for making tire with tie bar |
| JP4974057B2 (ja) * | 2005-01-31 | 2012-07-11 | 味の素株式会社 | 血糖降下剤を含有する、耐糖能異常、境界型糖尿病、インスリン抵抗性及び高インスリン血症の改善ないし治療用医薬組成物 |
| JPWO2008072532A1 (ja) * | 2006-12-07 | 2010-03-25 | 第一三共株式会社 | 貯蔵安定性が改善された医薬組成物 |
| WO2008072533A1 (ja) * | 2006-12-07 | 2008-06-19 | Daiichi Sankyo Company, Limited | 固形製剤の製造方法 |
| WO2008072535A1 (ja) * | 2006-12-07 | 2008-06-19 | Daiichi Sankyo Company, Limited | 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物 |
| US20100004279A1 (en) * | 2006-12-07 | 2010-01-07 | Tomoyuki Watanabe | Solid medicinal preparation containing mannitol or lactose |
| TWI405574B (zh) * | 2007-06-21 | 2013-08-21 | Otsuka Pharma Co Ltd | 藥學固體製劑及其製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6354321A (ja) * | 1985-03-27 | 1988-03-08 | Ajinomoto Co Inc | 血糖降下剤 |
| JP3586471B2 (ja) * | 1991-06-25 | 2004-11-10 | 三菱ウェルファーマ株式会社 | トラセミド含有医薬組成物 |
| DK0526171T3 (da) | 1991-07-30 | 1997-08-25 | Ajinomoto Kk | Krystaller af N-(trans-4-isopropylcyclohexylcarbonyl)-Dphenylalanin og fremgangsmåder til fremstilling deraf |
| EP0614358A1 (de) * | 1991-11-26 | 1994-09-14 | Warner-Lambert Company | Verfahren und zusammensetzung für die entwicklung einer gemfibrozil dosierungsform mit kontrollierter freigabe |
| KR100343062B1 (ko) * | 1996-11-15 | 2002-07-02 | 에가시라 구니오 | 정제 조성물 |
-
1997
- 1997-11-14 KR KR1019997004308A patent/KR100343062B1/ko not_active Expired - Lifetime
- 1997-11-14 CA CA002271865A patent/CA2271865C/en not_active Expired - Lifetime
- 1997-11-14 AT AT97912459T patent/ATE322260T1/de not_active IP Right Cessation
- 1997-11-14 WO PCT/JP1997/004152 patent/WO1998022105A1/ja not_active Ceased
- 1997-11-14 EP EP10010714A patent/EP2277517A1/de not_active Withdrawn
- 1997-11-14 PT PT97912459T patent/PT965339E/pt unknown
- 1997-11-14 ES ES97912459T patent/ES2257772T3/es not_active Expired - Lifetime
- 1997-11-14 EP EP05014497A patent/EP1586314B1/de not_active Expired - Lifetime
- 1997-11-14 AT AT05014497T patent/ATE503472T1/de active
- 1997-11-14 DK DK05014497.1T patent/DK1586314T3/da active
- 1997-11-14 DE DE69735644T patent/DE69735644T2/de not_active Expired - Lifetime
- 1997-11-14 ES ES05014497T patent/ES2364145T3/es not_active Expired - Lifetime
- 1997-11-14 EP EP97912459A patent/EP0965339B1/de not_active Expired - Lifetime
- 1997-11-14 AU AU49654/97A patent/AU718350B2/en not_active Ceased
- 1997-11-14 DE DE69740161T patent/DE69740161D1/de not_active Expired - Lifetime
- 1997-11-14 TW TW086117009A patent/TW492878B/zh not_active IP Right Cessation
- 1997-11-14 JP JP32974597A patent/JP4171091B2/ja not_active Expired - Lifetime
- 1997-11-14 PT PT05014497T patent/PT1586314E/pt unknown
- 1997-11-14 CN CNB971811407A patent/CN1245158C/zh not_active Expired - Lifetime
-
1999
- 1999-05-14 US US09/311,060 patent/US6143323A/en not_active Expired - Lifetime
-
2000
- 2000-09-29 US US09/672,896 patent/US6296872B1/en not_active Expired - Lifetime
-
2001
- 2001-08-03 US US09/920,830 patent/US6641841B2/en not_active Expired - Lifetime
-
2003
- 2003-02-05 US US10/358,324 patent/US6844008B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69740161D1 (de) | 2011-05-12 |
| JP4171091B2 (ja) | 2008-10-22 |
| EP2277517A1 (de) | 2011-01-26 |
| ATE322260T1 (de) | 2006-04-15 |
| KR100343062B1 (ko) | 2002-07-02 |
| US6143323A (en) | 2000-11-07 |
| EP0965339B1 (de) | 2006-04-05 |
| JPH10194969A (ja) | 1998-07-28 |
| EP1586314A1 (de) | 2005-10-19 |
| CA2271865A1 (en) | 1998-05-28 |
| US6641841B2 (en) | 2003-11-04 |
| DE69735644D1 (de) | 2006-05-18 |
| WO1998022105A1 (en) | 1998-05-28 |
| ES2364145T3 (es) | 2011-08-25 |
| DE69735644T2 (de) | 2007-05-03 |
| US6296872B1 (en) | 2001-10-02 |
| KR20000053312A (ko) | 2000-08-25 |
| PT965339E (pt) | 2006-06-30 |
| PT1586314E (pt) | 2011-07-01 |
| US20030147951A1 (en) | 2003-08-07 |
| DK1586314T3 (da) | 2011-06-20 |
| EP1586314B1 (de) | 2011-03-30 |
| US6844008B2 (en) | 2005-01-18 |
| US20020028239A1 (en) | 2002-03-07 |
| CN1242704A (zh) | 2000-01-26 |
| AU4965497A (en) | 1998-06-10 |
| CN1245158C (zh) | 2006-03-15 |
| TW492878B (en) | 2002-07-01 |
| CA2271865C (en) | 2003-10-14 |
| AU718350B2 (en) | 2000-04-13 |
| EP0965339A4 (de) | 2003-04-23 |
| EP0965339A1 (de) | 1999-12-22 |
| ES2257772T3 (es) | 2006-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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