ATE497958T1 - Verfahren zur herstellung von synthetischen derivaten von dibenzylbutyrolacton-lignanen mit antichagas eigenschaften - Google Patents
Verfahren zur herstellung von synthetischen derivaten von dibenzylbutyrolacton-lignanen mit antichagas eigenschaftenInfo
- Publication number
- ATE497958T1 ATE497958T1 AT03709465T AT03709465T ATE497958T1 AT E497958 T1 ATE497958 T1 AT E497958T1 AT 03709465 T AT03709465 T AT 03709465T AT 03709465 T AT03709465 T AT 03709465T AT E497958 T1 ATE497958 T1 AT E497958T1
- Authority
- AT
- Austria
- Prior art keywords
- cubebin
- lignans
- derivatives
- antichagas
- properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR0201237-5A BR0201237A (pt) | 2002-03-25 | 2002-03-25 | Processo de obtenção de lignanas dibenzilbutirolactÈnicas, processo de obtenção de derivados sintéticos de lignanas ostentando atividades quimioprofilática e terapêutica antichagásica |
| PCT/BR2003/000045 WO2003080600A1 (en) | 2002-03-25 | 2003-03-25 | Process to obtain dibenzylbutyrolactonic lignans; process to obtain synthetic derivatives from lignanes bearing anti-chagas chemoprophylactic and therapeutical activities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE497958T1 true ATE497958T1 (de) | 2011-02-15 |
Family
ID=39303809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03709465T ATE497958T1 (de) | 2002-03-25 | 2003-03-25 | Verfahren zur herstellung von synthetischen derivaten von dibenzylbutyrolacton-lignanen mit antichagas eigenschaften |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7317114B2 (de) |
| EP (1) | EP1487825B1 (de) |
| JP (2) | JP2005532277A (de) |
| AT (1) | ATE497958T1 (de) |
| AU (1) | AU2003213896A1 (de) |
| BR (1) | BR0201237A (de) |
| DE (1) | DE60335980D1 (de) |
| ES (1) | ES2362260T3 (de) |
| WO (1) | WO2003080600A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0501542A (pt) * | 2005-04-28 | 2006-12-12 | Fundacao De Amparo A Pesquisa | processo de obtenção de lignanas dibenzilbutirolactÈnicas, tetrahidrofuránicas e de seus derivados sintéticos e semi-sintéticos, suas atividades analgésica e antiinflamatória, formulações tópicas e/ou sistêmicas contendo tais lignanas e respectivo método terapêutico |
| BRPI0503951A (pt) * | 2005-07-15 | 2007-03-06 | Fundacao De Amparo A Pesquisa | processo de obtenção de derivados sintéticos e semi-sintéticos de lignanas, suas atividades antiparasitárias e respectivas formulações farmacêuticas, englobando o método terapêutico utilizando tais lignanas no tratamento de parasitoses |
| CH698627B1 (de) * | 2007-08-16 | 2009-09-15 | Alpinia Laudanum Inst Of Phytopharmaceutical | Herstellung und Verwendung von Extrakten oder Extraktivstoffen aus Piper cubeba L. als wirksame Bestandteile in einem Medikament zur Behandlung von Krebserkrankungen. |
| WO2011075801A1 (pt) | 2009-12-21 | 2011-06-30 | Acef S.A. | Cubebina, lignana dibenzilbutirolactólica, seus derivados semi-sintéticos e sintéticos, bem como outras lignanas e neolignanas como agente vasodilatador na terapia da disfunção erétil |
| CN102603754B (zh) * | 2012-04-06 | 2015-06-17 | 苏州大学 | 一种两面针喹诺酮类生物碱的制备及应用 |
| WO2014086379A1 (en) | 2012-12-03 | 2014-06-12 | Alpinia Laudanum Institute Of Phytopharmaceutical Sciences Ag | Lignan compositions |
| JP7197908B2 (ja) * | 2019-03-04 | 2022-12-28 | 株式会社ナチュファルマ琉球 | 骨減少性疾患の予防及び／又は治療用組成物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK346987D0 (da) * | 1987-07-06 | 1987-07-06 | Hans Goeran Magnusson | Fremgangsmaade til fremstilling af tetrahydrofuranforbindelser |
-
2002
- 2002-03-25 BR BR0201237-5A patent/BR0201237A/pt active Search and Examination
-
2003
- 2003-03-25 EP EP03709465A patent/EP1487825B1/de not_active Expired - Lifetime
- 2003-03-25 JP JP2003578354A patent/JP2005532277A/ja active Pending
- 2003-03-25 ES ES03709465T patent/ES2362260T3/es not_active Expired - Lifetime
- 2003-03-25 AT AT03709465T patent/ATE497958T1/de not_active IP Right Cessation
- 2003-03-25 DE DE60335980T patent/DE60335980D1/de not_active Expired - Lifetime
- 2003-03-25 WO PCT/BR2003/000045 patent/WO2003080600A1/en active Application Filing
- 2003-03-25 US US10/508,875 patent/US7317114B2/en not_active Expired - Fee Related
- 2003-03-25 AU AU2003213896A patent/AU2003213896A1/en not_active Abandoned
-
2007
- 2007-12-06 US US11/951,460 patent/US7521569B2/en not_active Expired - Fee Related
-
2010
- 2010-12-10 JP JP2010275582A patent/JP2011098968A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE60335980D1 (de) | 2011-03-24 |
| US20080090901A1 (en) | 2008-04-17 |
| EP1487825A1 (de) | 2004-12-22 |
| US20050154215A1 (en) | 2005-07-14 |
| ES2362260T3 (es) | 2011-06-30 |
| WO2003080600A1 (en) | 2003-10-02 |
| JP2005532277A (ja) | 2005-10-27 |
| US7317114B2 (en) | 2008-01-08 |
| JP2011098968A (ja) | 2011-05-19 |
| US7521569B2 (en) | 2009-04-21 |
| AU2003213896A1 (en) | 2003-10-08 |
| EP1487825B1 (de) | 2011-02-09 |
| BR0201237A (pt) | 2003-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |