ATE497950T1 - Isochinolin-1,3,4-trion, synthetisches verfahren und dessen verwendung - Google Patents
Isochinolin-1,3,4-trion, synthetisches verfahren und dessen verwendungInfo
- Publication number
- ATE497950T1 ATE497950T1 AT04738186T AT04738186T ATE497950T1 AT E497950 T1 ATE497950 T1 AT E497950T1 AT 04738186 T AT04738186 T AT 04738186T AT 04738186 T AT04738186 T AT 04738186T AT E497950 T1 ATE497950 T1 AT E497950T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- alkoxyl
- groups including
- hydroxyl
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNA03129250XA CN1566099A (zh) | 2003-06-13 | 2003-06-13 | 异喹啉-1,3,4-三酮类化合物、制备方法及其用途 |
PCT/CN2004/000567 WO2004111010A1 (fr) | 2003-06-13 | 2004-05-31 | Isoquinoline-1,3,4-trione, procede synthetique et utilisation correspondante |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE497950T1 true ATE497950T1 (de) | 2011-02-15 |
Family
ID=33546182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04738186T ATE497950T1 (de) | 2003-06-13 | 2004-05-31 | Isochinolin-1,3,4-trion, synthetisches verfahren und dessen verwendung |
Country Status (6)
Country | Link |
---|---|
US (1) | US7683073B2 (de) |
EP (1) | EP1640367B1 (de) |
CN (1) | CN1566099A (de) |
AT (1) | ATE497950T1 (de) |
DE (1) | DE602004031338D1 (de) |
WO (1) | WO2004111010A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7402596B2 (en) * | 2005-03-24 | 2008-07-22 | Renovis, Inc. | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof |
WO2007109154A2 (en) * | 2006-03-16 | 2007-09-27 | Renovis, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
TWI464148B (zh) * | 2006-03-16 | 2014-12-11 | Evotec Us Inc | 作為p2x7調節劑之雙環雜芳基化合物與其用途 |
FR2911143A1 (fr) * | 2007-01-05 | 2008-07-11 | Servier Lab | Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives. |
US8093265B2 (en) | 2007-03-09 | 2012-01-10 | Renovis, Inc. | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof |
EP2729007A1 (de) | 2011-07-04 | 2014-05-14 | Bayer Intellectual Property GmbH | Verwendung substituierter isochinolinone, isochinolindione, isochinolintrione und dihydroisochinolinone oder jeweils deren salze als wirkstoffe gegen abiotischen pflanzenstress |
JP6280912B2 (ja) * | 2013-03-14 | 2018-02-14 | 武田薬品工業株式会社 | 複素環化合物 |
WO2015002231A1 (ja) | 2013-07-03 | 2015-01-08 | 武田薬品工業株式会社 | 複素環化合物 |
EP3018123B1 (de) | 2013-07-03 | 2023-05-10 | Takeda Pharmaceutical Company Limited | Amidverbindung |
AU2015210833B2 (en) | 2014-02-03 | 2019-01-03 | Vitae Pharmaceuticals, Llc | Dihydropyrrolopyridine inhibitors of ROR-gamma |
JP6564029B2 (ja) | 2014-10-14 | 2019-08-21 | ヴァイティー ファーマシューティカルズ,エルエルシー | Ror−ガンマのジヒドロピロロピリジン阻害剤 |
US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
EP3331876B1 (de) | 2015-08-05 | 2020-10-07 | Vitae Pharmaceuticals, LLC | Modulatoren von ror-gamma |
MX2018006223A (es) | 2015-11-20 | 2018-12-19 | Vitae Pharmaceuticals Inc | Moduladores de ror-gamma. |
TW202220968A (zh) | 2016-01-29 | 2022-06-01 | 美商維它藥物有限責任公司 | ROR-γ調節劑 |
US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
EP3658555A1 (de) | 2017-07-24 | 2020-06-03 | Vitae Pharmaceuticals, LLC | Ror-inhibitoren |
WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5843943A (en) * | 1994-12-29 | 1998-12-01 | The Regents Of The University Of California | Compounds for inhibition of ceramide-mediated signal transduction |
-
2003
- 2003-06-13 CN CNA03129250XA patent/CN1566099A/zh active Pending
-
2004
- 2004-05-31 EP EP04738186A patent/EP1640367B1/de not_active Expired - Lifetime
- 2004-05-31 WO PCT/CN2004/000567 patent/WO2004111010A1/zh active Application Filing
- 2004-05-31 DE DE602004031338T patent/DE602004031338D1/de not_active Expired - Lifetime
- 2004-05-31 AT AT04738186T patent/ATE497950T1/de not_active IP Right Cessation
-
2005
- 2005-12-13 US US11/301,638 patent/US7683073B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1566099A (zh) | 2005-01-19 |
US7683073B2 (en) | 2010-03-23 |
EP1640367A1 (de) | 2006-03-29 |
US20060135557A1 (en) | 2006-06-22 |
EP1640367A4 (de) | 2008-12-10 |
WO2004111010A1 (fr) | 2004-12-23 |
EP1640367B1 (de) | 2011-02-09 |
DE602004031338D1 (de) | 2011-03-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE497950T1 (de) | Isochinolin-1,3,4-trion, synthetisches verfahren und dessen verwendung | |
TW200505907A (en) | Piperidine-benzenesulfonamide derivatives | |
MY141308A (en) | Malonamide derivatives | |
MY140470A (en) | Substituted acylpiperazine derivatives | |
NO994452D0 (no) | Substituerte 4-arylmetylen-2-imino-2,3-dihydrotiazoler og derivater, og deres farmasöytiske anvendelse | |
DE3855144T2 (de) | Verwendung von bestimmten 5-HT3-Rezeptorantagonisten zur Behandlung von Eingeweideschmerzen | |
UA80841C2 (en) | Fatty acid amide hydrolase inhibitors, pharmaceutical composition (variants) and method to treat appetite disorders, glaucoma, pain, and related neurological disorders (variants) | |
ATE556085T1 (de) | Phosphoramiditverbindung und verfahren zur herstellung von oligo-rna | |
DE3850306T2 (de) | Camptothecin-Derivate und Verfahren zu ihrer Herstellung. | |
WO2007071632A3 (en) | 2-pyridin-2-yl-quinazoline derivatives as potassium channel modulating agents for the treatment of respiratory diseases | |
SE0202134D0 (sv) | Therapeutic agents | |
MY124316A (en) | Pyridazino quinoline compounds. | |
CY1109220T1 (el) | Παραγωγα ν-ακυλαμινοβενζολιου ως εκλεκτικοι αναστολεις της οξειδασης μονοαμινης β | |
ES2132284T3 (es) | Derivados de carbamato de 2-(piperidin-4-il, piridin-4-il y tetrahidropiridin-4-il)-benzofurano-7, su preparacion y su uso como inhibidores de acetilcolinesterasa. | |
DE602004031722D1 (de) | Kondensierte bizyklisch substituierte amine als histamin 3 rezeptor liganden | |
ATE201687T1 (de) | Galanthamin-derivat, ein verfahren zu seiner herstellung und seine verwendung als medikament | |
HUP0303034A2 (hu) | Új 7-azaindol-származékok, foszfodiészteráz-4 inhibitorjakénti alkalmazásuk és eljárás az előállításukra | |
WO2003082861A3 (en) | Morpholinyl-urea derivatives for use of the treatment of inflammatory diseases | |
ATE211474T1 (de) | Galanthamin derivate, verfahren zu ihrer herstellung und ihre verwendung als medikamente | |
MXPA04005940A (es) | Acidos 3-(imidazolil)-2-aminopropanoicos. | |
ATE66913T1 (de) | Amidverbindungen, verfahren zu ihrer herstellung und zusammensetzung zur aktivierung gastromotorischer funktionen. | |
RU2004117531A (ru) | Использование производных 2-амино-4-пиридилметилтиазолина в качестве ингибиторов индуцибельной no-синтазы | |
NO941516L (no) | 3-kinolylsubstituerte dihydropyridiner, fremgangsmåter for deres fremstilling og deres anvendelse | |
ATE211137T1 (de) | Substituierte benzylthienylpiperazine, ihre anwendung als arzneimittel und verfahren für ihre herstellung | |
DE602004025935D1 (de) | Histondeacetylaseinhibitor und verfahren zu dessen herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |