ATE496923T1 - Neues verfahren für die zubereitung von 3-methyl- 4-phenylisoxazoloä3,4-düpyridazin-7(6h)-on - Google Patents

Neues verfahren für die zubereitung von 3-methyl- 4-phenylisoxazoloä3,4-düpyridazin-7(6h)-on

Info

Publication number
ATE496923T1
ATE496923T1 AT08707692T AT08707692T ATE496923T1 AT E496923 T1 ATE496923 T1 AT E496923T1 AT 08707692 T AT08707692 T AT 08707692T AT 08707692 T AT08707692 T AT 08707692T AT E496923 T1 ATE496923 T1 AT E496923T1
Authority
AT
Austria
Prior art keywords
düpyridazine
methyl
preparation
new process
new
Prior art date
Application number
AT08707692T
Other languages
English (en)
Inventor
Hereu Iolanda Marchueta
Masia Xavier Serra
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Sa filed Critical Almirall Sa
Application granted granted Critical
Publication of ATE496923T1 publication Critical patent/ATE496923T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT08707692T 2007-03-02 2008-02-13 Neues verfahren für die zubereitung von 3-methyl- 4-phenylisoxazoloä3,4-düpyridazin-7(6h)-on ATE496923T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200700564A ES2320954B1 (es) 2007-03-02 2007-03-02 Nuevo procedimiento de preparacion de 3-metil-4-fenilisoxazolo (3,4-d)iridazin-7(6h)-ona.
PCT/EP2008/001080 WO2008107064A1 (en) 2007-03-02 2008-02-13 New process for preparing 3-methyl-4-phenylisoxazolo[3,4-d]pyridazin-7(6h)-one

Publications (1)

Publication Number Publication Date
ATE496923T1 true ATE496923T1 (de) 2011-02-15

Family

ID=38617235

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08707692T ATE496923T1 (de) 2007-03-02 2008-02-13 Neues verfahren für die zubereitung von 3-methyl- 4-phenylisoxazoloä3,4-düpyridazin-7(6h)-on

Country Status (23)

Country Link
US (1) US20100137591A1 (de)
EP (1) EP2125830B1 (de)
JP (1) JP2010520158A (de)
KR (1) KR20090116753A (de)
CN (1) CN101679453A (de)
AR (1) AR065511A1 (de)
AT (1) ATE496923T1 (de)
AU (1) AU2008224206A1 (de)
BR (1) BRPI0807273A2 (de)
CA (1) CA2679619A1 (de)
CL (1) CL2008000598A1 (de)
DE (1) DE602008004742D1 (de)
EC (1) ECSP099558A (de)
ES (1) ES2320954B1 (de)
IL (1) IL200166A0 (de)
MX (1) MX2009009232A (de)
NZ (1) NZ578671A (de)
PE (1) PE20081793A1 (de)
RU (1) RU2009136314A (de)
TW (1) TW200844105A (de)
UY (1) UY30913A1 (de)
WO (1) WO2008107064A1 (de)
ZA (1) ZA200905193B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2211344B1 (es) * 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
ES2251866B1 (es) 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
ES2251867B1 (es) * 2004-06-21 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679696A (en) * 1992-07-28 1997-10-21 Rhone-Poulenc Rorer Limited Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic-or heteroatom-containing linking group
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
DE19540475A1 (de) * 1995-10-20 1997-04-24 Schering Ag Chirale Methylphenyloxazolidinone
PL329922A1 (en) * 1996-05-20 1999-04-26 Darwin Discovery Ltd Quinoline carboxamides as inhibitors of the tumour necrosis factor and of phosphodiesterase
RU2162467C2 (ru) * 1996-05-20 2001-01-27 Дарвин Дискавери Лимитед Карбоксамиды бензофурана и их фармацевтическая композиция
AU751453C (en) * 1997-11-25 2003-04-10 Warner-Lambert Company Benzenesulfonamide inhibitors of PDE-IV and their therapeutic use
WO2000050402A1 (en) * 1999-02-25 2000-08-31 Merck Frosst Canada & Co. Pde iv inhibiting compounds, compositions and methods of treatment
US6699890B2 (en) * 2000-12-22 2004-03-02 Memory Pharmaceuticals Corp. Phosphodiesterase 4 inhibitors
CN1604776A (zh) * 2001-10-16 2005-04-06 记忆药物公司 作为用于治疗神经病综合症的pde-4抑制剂的4-(4-烷氧基-3-羟基苯基)-2-吡咯烷酮衍生物
AR037517A1 (es) * 2001-11-05 2004-11-17 Novartis Ag Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
ES2195785B1 (es) * 2002-05-16 2005-03-16 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
CN100513397C (zh) * 2002-11-19 2009-07-15 记忆药物公司 磷酸二酯酶4抑制剂
ES2211344B1 (es) * 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
RU2379292C2 (ru) * 2003-04-18 2010-01-20 Мемори Фармасьютиклз Корпорейшн Производные пиразола в качестве ингибиторов фосфодиэстеразы 4
ES2232306B1 (es) * 2003-11-10 2006-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
ES2251866B1 (es) * 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
ES2251867B1 (es) * 2004-06-21 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
EP2222639A1 (de) * 2007-11-21 2010-09-01 Decode Genetics EHF Biaryle als pde4-inhibitoren zur behandlung von lungen- und herz-kreislauf-erkrankungen

Also Published As

Publication number Publication date
JP2010520158A (ja) 2010-06-10
US20100137591A1 (en) 2010-06-03
KR20090116753A (ko) 2009-11-11
UY30913A1 (es) 2008-07-31
ES2320954A1 (es) 2009-05-29
AR065511A1 (es) 2009-06-10
NZ578671A (en) 2011-04-29
IL200166A0 (en) 2010-04-15
EP2125830B1 (de) 2011-01-26
ZA200905193B (en) 2010-05-26
ES2320954B1 (es) 2010-03-16
CA2679619A1 (en) 2008-09-12
EP2125830A1 (de) 2009-12-02
MX2009009232A (es) 2009-10-12
ECSP099558A (es) 2009-09-29
CN101679453A (zh) 2010-03-24
BRPI0807273A2 (pt) 2014-04-29
CL2008000598A1 (es) 2008-09-05
TW200844105A (en) 2008-11-16
DE602008004742D1 (de) 2011-03-10
WO2008107064A1 (en) 2008-09-12
AU2008224206A1 (en) 2008-09-12
RU2009136314A (ru) 2011-04-10
PE20081793A1 (es) 2008-12-18

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