ATE492562T1 - Rekombinanter antikörper gegen humanen insulin- like growth factor - Google Patents
Rekombinanter antikörper gegen humanen insulin- like growth factorInfo
- Publication number
- ATE492562T1 ATE492562T1 AT04773541T AT04773541T ATE492562T1 AT E492562 T1 ATE492562 T1 AT E492562T1 AT 04773541 T AT04773541 T AT 04773541T AT 04773541 T AT04773541 T AT 04773541T AT E492562 T1 ATE492562 T1 AT E492562T1
- Authority
- AT
- Austria
- Prior art keywords
- antibody
- growth factor
- human insulin
- antibody fragment
- recombinant antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003331509 | 2003-09-24 | ||
PCT/JP2004/014453 WO2005028515A1 (ja) | 2003-09-24 | 2004-09-24 | ヒトインスリン様成長因子に対する遺伝子組換え抗体 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE492562T1 true ATE492562T1 (de) | 2011-01-15 |
Family
ID=34373044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04773541T ATE492562T1 (de) | 2003-09-24 | 2004-09-24 | Rekombinanter antikörper gegen humanen insulin- like growth factor |
Country Status (7)
Country | Link |
---|---|
US (1) | US7498415B2 (de) |
EP (1) | EP1676862B1 (de) |
JP (1) | JP4620591B2 (de) |
AT (1) | ATE492562T1 (de) |
CA (1) | CA2540138C (de) |
DE (1) | DE602004030700D1 (de) |
WO (1) | WO2005028515A1 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8195659B2 (en) * | 2005-08-23 | 2012-06-05 | Ricoh Co. Ltd. | Integration and use of mixed media documents |
EP1979001B1 (de) | 2005-12-13 | 2012-04-11 | Medimmune Limited | Proteine die spezifisch insulin-ähnliche wachstumsfaktoren binden, und deren anwendungen |
PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
CA2723722A1 (en) * | 2008-05-09 | 2009-11-12 | Dyax Corp. | Igf-ii/gf-iie binding proteins |
WO2010045315A1 (en) | 2008-10-14 | 2010-04-22 | Dyax Corp. | Use of igf-ii/igf-iie binding for the treatment and prevention of systemic sclerosis associated pulmonary fibrosis |
HUE026374T2 (en) | 2008-12-12 | 2016-05-30 | Boehringer Ingelheim Int | Anti-IGF antibody |
US20100316639A1 (en) | 2009-06-16 | 2010-12-16 | Genentech, Inc. | Biomarkers for igf-1r inhibitor therapy |
CA2774953A1 (en) * | 2009-10-07 | 2011-04-14 | The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services | Human domain antibodies against components of the human insulin-like growth factor (igf) system |
WO2013015821A1 (en) | 2011-07-22 | 2013-01-31 | The Research Foundation Of State University Of New York | Antibodies to the b12-transcobalamin receptor |
US9120858B2 (en) | 2011-07-22 | 2015-09-01 | The Research Foundation Of State University Of New York | Antibodies to the B12-transcobalamin receptor |
CA2896082A1 (en) * | 2012-12-21 | 2014-06-26 | Joel R. L. Ehrenkranz | Supplements and monitoring systems for dosing of the supplements |
US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
SG11202010025YA (en) | 2018-05-31 | 2020-11-27 | Glyconex Inc | Therapeutic antibodies binding to biantennary lewis b and lewis y antigens |
CA3105222A1 (en) | 2018-07-17 | 2020-01-23 | Humabs Biomed Sa | Antibodies against campylobacter species |
JP2023512684A (ja) | 2020-02-03 | 2023-03-28 | ヴィア・バイオテクノロジー・インコーポレイテッド | Sars-cov-2に対する抗体およびそれを使用する方法 |
DK3872091T3 (da) | 2020-02-26 | 2023-09-11 | Vir Biotechnology Inc | Antistoffer mod sars-cov-2 |
WO2021203053A1 (en) | 2020-04-03 | 2021-10-07 | Vir Biotechnology, Inc. | Immunotherapy targeting a conserved region in sars coronaviruses |
BR112022020706A2 (pt) | 2020-04-14 | 2022-11-29 | Vir Biotechnology Inc | Anticorpos contra sars-cov-2 e métodos de uso dos mesmos |
AU2021268361A1 (en) | 2020-05-08 | 2022-12-08 | Vir Biotechnology, Inc. | Antibodies against SARS-CoV-2 |
WO2021247925A1 (en) | 2020-06-03 | 2021-12-09 | Vir Biotechnology, Inc. | Structure-guided immunotherapy against sars-cov-2 |
AU2021288203A1 (en) | 2020-06-12 | 2023-01-19 | Vir Biotechnology, Inc. | Antibody therapies for SARS-CoV-2 infection |
EP4217385A2 (de) | 2020-09-28 | 2023-08-02 | VIR Biotechnology, Inc. | Antikörper gegen sars-cov-2 |
TW202235105A (zh) | 2020-11-23 | 2022-09-16 | 美商維爾生物科技股份有限公司 | 抗流感抗體及其組合 |
CA3197537A1 (en) | 2020-11-23 | 2022-05-27 | Davide Corti | Antibodies against influenza a viruses |
US20240092876A1 (en) | 2020-11-23 | 2024-03-21 | Vir Biotechnology, Inc. | Broadly neutralizing antibodies against influenza neuraminidase |
TW202235107A (zh) | 2020-11-25 | 2022-09-16 | 美商維爾生物科技股份有限公司 | 結合至多種乙型冠狀病毒的抗體 |
US20220259319A1 (en) * | 2021-01-21 | 2022-08-18 | Twist Bioscience Corporation | Methods and compositions relating to adenosine receptors |
WO2022204202A1 (en) | 2021-03-23 | 2022-09-29 | Vir Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
AU2022280767A1 (en) | 2021-05-24 | 2024-01-18 | Humabs Biomed Sa | Engineered polypeptides |
WO2023034871A1 (en) | 2021-09-01 | 2023-03-09 | Vir Biotechnology, Inc. | High concentration antibody therapies for sars-cov-2 infection |
WO2023034866A1 (en) | 2021-09-01 | 2023-03-09 | Vir Biotechnology, Inc. | Antibody therapies for sars-cov-2 infection in pediatric subjects |
WO2023201256A1 (en) | 2022-04-12 | 2023-10-19 | Vir Biotechnology, Inc. | High dose antibody therapies for sars-cov-2 infection |
WO2023230448A1 (en) | 2022-05-23 | 2023-11-30 | Vir Biotechnology, Inc. | Combination immunotherapy for influenza |
WO2023230445A2 (en) | 2022-05-23 | 2023-11-30 | Humabs Biomed Sa | Broadly neutralizing antibodies against influenza neuraminidase |
WO2023245078A1 (en) | 2022-06-15 | 2023-12-21 | Humabs Biomed Sa | Anti-parvovirus antibodies and uses thereof |
WO2024006472A1 (en) | 2022-06-30 | 2024-01-04 | Vir Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
WO2024026411A1 (en) | 2022-07-27 | 2024-02-01 | Humabs Biomed Sa | Broadly neutralizing antibodies against rsv and mpv paramyxoviruses |
WO2024112818A1 (en) | 2022-11-22 | 2024-05-30 | Humabs Biomed Sa | Engineered anti-sars-cov-2 antibodies and uses thereof |
WO2024118998A2 (en) | 2022-12-01 | 2024-06-06 | Vir Biotechnology, Inc. | Engineered anti-sars-cov-2 antibodies and methods of using the same |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2433883C2 (de) | 1973-07-20 | 1986-03-27 | Research Corp., New York, N.Y. | Verwendung von physiologisch aktiven Polypeptiden |
WO1985003934A1 (en) | 1984-03-06 | 1985-09-12 | Takeda Chemical Industries, Ltd. | Chemically modified protein and process for its preparation |
AU1232188A (en) * | 1987-05-29 | 1988-12-01 | Mallinckrodt, Inc. | Novel pair of monoclonal antibodies to insulin-like growth factor i permits immunometric assay for igf-i |
JP2958019B2 (ja) | 1988-05-06 | 1999-10-06 | 住友製薬株式会社 | ポリエチレングリコール誘導体、修飾ペプチドおよびその製造方法 |
JPH02257891A (ja) | 1989-03-31 | 1990-10-18 | Kyowa Hakko Kogyo Co Ltd | 組換え動物細胞による蛋白質の製造 |
CA2058041A1 (en) | 1990-06-27 | 1991-12-28 | Katsuichi Sakano | Anti-igf-ii monoclonal antibody |
GB9217696D0 (en) * | 1992-08-20 | 1992-09-30 | Agricultural & Food Res | Use of specific binding molecules |
AU690474B2 (en) | 1995-09-11 | 1998-04-23 | Kyowa Hakko Kirin Co., Ltd. | Antibody againts alpha-chain of human interleukin 5 receptor |
OA12589A (en) * | 2001-01-05 | 2006-06-08 | Abgenix Inc | Antibodies to insulin-like growth factor i receptor. |
ATE444972T1 (de) | 2002-04-30 | 2009-10-15 | Kyowa Hakko Kirin Co Ltd | ANTIKÖRPER GEGEN DEN HUMANEN ßINSULIN-LIKEß WACHSTUMSFAKTOR |
JP2003310275A (ja) * | 2002-04-30 | 2003-11-05 | Kyowa Hakko Kogyo Co Ltd | ヒトインスリン様成長因子に対する遺伝子組換え抗体 |
WO2005018671A1 (ja) * | 2003-08-21 | 2005-03-03 | Kyowa Hakko Kogyo Co., Ltd. | 癌転移阻害剤 |
-
2004
- 2004-09-24 US US10/573,378 patent/US7498415B2/en not_active Expired - Fee Related
- 2004-09-24 AT AT04773541T patent/ATE492562T1/de not_active IP Right Cessation
- 2004-09-24 JP JP2005514152A patent/JP4620591B2/ja not_active Expired - Fee Related
- 2004-09-24 CA CA2540138A patent/CA2540138C/en not_active Expired - Fee Related
- 2004-09-24 EP EP04773541A patent/EP1676862B1/de not_active Not-in-force
- 2004-09-24 WO PCT/JP2004/014453 patent/WO2005028515A1/ja active Application Filing
- 2004-09-24 DE DE602004030700T patent/DE602004030700D1/de active Active
Also Published As
Publication number | Publication date |
---|---|
CA2540138C (en) | 2013-07-30 |
EP1676862A1 (de) | 2006-07-05 |
EP1676862A4 (de) | 2007-08-08 |
JP4620591B2 (ja) | 2011-01-26 |
CA2540138A1 (en) | 2005-03-31 |
JPWO2005028515A1 (ja) | 2007-11-15 |
EP1676862B1 (de) | 2010-12-22 |
WO2005028515A1 (ja) | 2005-03-31 |
US7498415B2 (en) | 2009-03-03 |
US20060240015A1 (en) | 2006-10-26 |
DE602004030700D1 (de) | 2011-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |