ATE488556T1 - Verbesserte photostabile fret-kompetente biarsentetracysteinsonden auf basis fluorierter fluoreszeine - Google Patents

Verbesserte photostabile fret-kompetente biarsentetracysteinsonden auf basis fluorierter fluoreszeine

Info

Publication number
ATE488556T1
ATE488556T1 AT07725771T AT07725771T ATE488556T1 AT E488556 T1 ATE488556 T1 AT E488556T1 AT 07725771 T AT07725771 T AT 07725771T AT 07725771 T AT07725771 T AT 07725771T AT E488556 T1 ATE488556 T1 AT E488556T1
Authority
AT
Austria
Prior art keywords
biarsentetracystone
fluorescine
fluorized
fret
competent
Prior art date
Application number
AT07725771T
Other languages
English (en)
Inventor
Elisabeth A Jares-Erijman
Carla C Spagnuolo
Rolf J Vermeij
Thomas M Jovin
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of ATE488556T1 publication Critical patent/ATE488556T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00Diaryl- or thriarylmethane dyes
    • C09B11/04Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/06Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
    • C09B11/08Phthaleins; Phenolphthaleins; Fluorescein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Coloring (AREA)
AT07725771T 2006-06-12 2007-06-01 Verbesserte photostabile fret-kompetente biarsentetracysteinsonden auf basis fluorierter fluoreszeine ATE488556T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06012026 2006-06-12
PCT/EP2007/004891 WO2007144077A2 (en) 2006-06-12 2007-06-01 Improved photostable fret-competent biarsenical-tetracysteine probes based on fluorinated fluoresceins

Publications (1)

Publication Number Publication Date
ATE488556T1 true ATE488556T1 (de) 2010-12-15

Family

ID=38691711

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07725771T ATE488556T1 (de) 2006-06-12 2007-06-01 Verbesserte photostabile fret-kompetente biarsentetracysteinsonden auf basis fluorierter fluoreszeine

Country Status (5)

Country Link
US (1) US20090098596A1 (de)
EP (1) EP2029673B1 (de)
AT (1) ATE488556T1 (de)
DE (1) DE602007010621D1 (de)
WO (1) WO2007144077A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010037001A1 (de) * 2010-08-16 2012-02-16 Evocatal Gmbh Neue Biosensoren und deren Verwendung
GB201019303D0 (en) 2010-11-15 2010-12-29 Strom Hans E P Agents and methods for visualising analytes
EP4111203A1 (de) * 2020-02-28 2023-01-04 Technische Universität Berlin Fluoreszierende sonden zum nachweis von verkalkungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162931A (en) * 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
US6054271A (en) * 1997-10-21 2000-04-25 The Regents Of The University Of California Methods of using synthetic molecules and target sequences
US6008378A (en) * 1997-10-21 1999-12-28 The Regents Of The University Of California Synthetic molecules that specifically react with target sequences
US7326771B2 (en) * 2003-08-25 2008-02-05 Monterey Bay Aquarium Research Institute Long-wavelength FPs
US20050176065A1 (en) * 2003-10-22 2005-08-11 Invitrogen Corporation Target sequences for synthetic molecules
US20050239135A1 (en) * 2003-10-24 2005-10-27 Bogoev Roumen A Compositions, methods and kits for biarsenical fluorophore labeling
EP1866387B1 (de) * 2005-03-09 2013-05-08 Cepheid Polare farbstoffe

Also Published As

Publication number Publication date
WO2007144077A2 (en) 2007-12-21
WO2007144077A3 (en) 2008-04-17
DE602007010621D1 (de) 2010-12-30
US20090098596A1 (en) 2009-04-16
EP2029673B1 (de) 2010-11-17
EP2029673A2 (de) 2009-03-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties