ATE488526T1 - Chimärer impfstoff für haemophilus influenzae- induzierte infektion - Google Patents
Chimärer impfstoff für haemophilus influenzae- induzierte infektionInfo
- Publication number
- ATE488526T1 ATE488526T1 AT06800001T AT06800001T ATE488526T1 AT E488526 T1 ATE488526 T1 AT E488526T1 AT 06800001 T AT06800001 T AT 06800001T AT 06800001 T AT06800001 T AT 06800001T AT E488526 T1 ATE488526 T1 AT E488526T1
- Authority
- AT
- Austria
- Prior art keywords
- haemophilus influenzae
- protein
- chimeric vaccine
- induced infection
- nthi
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000606790 Haemophilus Species 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
- 206010028347 Muscle twitching Diseases 0.000 abstract 1
- 101710167675 Outer membrane protein P5 Proteins 0.000 abstract 1
- 241001377010 Pila Species 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1242—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69764205P | 2005-07-08 | 2005-07-08 | |
| US80183506P | 2006-05-19 | 2006-05-19 | |
| PCT/US2006/026183 WO2007008527A2 (en) | 2005-07-08 | 2006-07-05 | Chimeric vaccine for haemophilus influenzae-induced disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE488526T1 true ATE488526T1 (de) | 2010-12-15 |
Family
ID=37441871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06800001T ATE488526T1 (de) | 2005-07-08 | 2006-07-05 | Chimärer impfstoff für haemophilus influenzae- induzierte infektion |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7811591B2 (enExample) |
| EP (2) | EP1904519B1 (enExample) |
| JP (2) | JP2009500037A (enExample) |
| AT (1) | ATE488526T1 (enExample) |
| CA (1) | CA2613970C (enExample) |
| DE (1) | DE602006018308D1 (enExample) |
| WO (1) | WO2007008527A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9812613D0 (en) * | 1998-06-11 | 1998-08-12 | Smithkline Beecham Biolog | Vaccine |
| ATE488526T1 (de) * | 2005-07-08 | 2010-12-15 | Nationwide Childrens Hospital | Chimärer impfstoff für haemophilus influenzae- induzierte infektion |
| TW201302779A (zh) * | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| GB201218660D0 (en) | 2012-10-17 | 2012-11-28 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| CN104853768B (zh) * | 2012-10-17 | 2019-04-19 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合物 |
| AU2014225330B2 (en) | 2013-03-08 | 2018-11-01 | Lauren O. Bakaletz | Transcutaneous dosage formulation |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US20180207067A1 (en) | 2015-07-14 | 2018-07-26 | Research Institute at Nationwide Children's Hospit al | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| HK1255383A1 (zh) | 2015-07-31 | 2019-08-16 | The Research Institute At Nationwide Children's Hospital | 去除生物膜的肽及抗體 |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| EP3565589A1 (en) | 2017-01-04 | 2019-11-13 | Research Institute at Nationwide Children's Hospital | Dnabii vaccines and antibodies with enhanced activity |
| EP3860718A4 (en) | 2018-10-05 | 2022-08-31 | Research Institute at Nationwide Children's Hospital | HMGB1 PROTEIN DERIVATIVES FOR BIOFILM REMOVAL |
| US12116614B2 (en) | 2020-06-30 | 2024-10-15 | Research Institute At Nationwide Children's Hospital | Methods for determining antibiotic sensitivity |
| CN112961241B (zh) * | 2020-06-30 | 2022-04-22 | 广州百暨基因科技有限公司 | 抗b7h3抗体及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US19005A (en) | 1857-12-29 | de witt | ||
| US697642A (en) | 1901-03-09 | 1902-04-15 | Liberty Millet | Process of strengthening clay hydraulic pipe, vases, crockery-ware, &c. |
| US801835A (en) | 1905-02-25 | 1905-10-17 | Rudolph H Apelt | Ball-bearing. |
| US1900504A (en) | 1930-11-25 | 1933-03-07 | Ingersoll Rand Co | Condensing apparatus |
| WO1994026304A1 (en) * | 1993-05-18 | 1994-11-24 | Ohio State Research Foundation | Otitis media vaccine |
| DE4336530C1 (de) | 1993-10-26 | 1995-04-13 | Max Planck Gesellschaft | Rekombinante PilC-Proteine, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US6355450B1 (en) | 1995-04-21 | 2002-03-12 | Human Genome Sciences, Inc. | Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof |
| US5843464A (en) * | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
| GB9812613D0 (en) * | 1998-06-11 | 1998-08-12 | Smithkline Beecham Biolog | Vaccine |
| ES2387215T3 (es) * | 2003-12-23 | 2012-09-18 | Nationwide Children's Hospital, Inc. | Pili de tipo IV de la Haemophilus influenzae |
| ATE488526T1 (de) * | 2005-07-08 | 2010-12-15 | Nationwide Childrens Hospital | Chimärer impfstoff für haemophilus influenzae- induzierte infektion |
-
2006
- 2006-07-05 AT AT06800001T patent/ATE488526T1/de not_active IP Right Cessation
- 2006-07-05 US US11/994,830 patent/US7811591B2/en active Active
- 2006-07-05 EP EP06800001A patent/EP1904519B1/en not_active Not-in-force
- 2006-07-05 JP JP2008520357A patent/JP2009500037A/ja active Pending
- 2006-07-05 DE DE602006018308T patent/DE602006018308D1/de active Active
- 2006-07-05 WO PCT/US2006/026183 patent/WO2007008527A2/en not_active Ceased
- 2006-07-05 EP EP10174620A patent/EP2298794A3/en not_active Withdrawn
- 2006-07-05 CA CA2613970A patent/CA2613970C/en not_active Expired - Fee Related
-
2009
- 2009-10-14 JP JP2009237768A patent/JP2010172332A/ja active Pending
-
2010
- 2010-10-05 US US12/898,287 patent/US8263363B2/en active Active
-
2012
- 2012-09-10 US US13/608,500 patent/US8741304B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20130064828A1 (en) | 2013-03-14 |
| EP1904519A2 (en) | 2008-04-02 |
| JP2010172332A (ja) | 2010-08-12 |
| EP1904519B1 (en) | 2010-11-17 |
| DE602006018308D1 (de) | 2010-12-30 |
| US8741304B2 (en) | 2014-06-03 |
| WO2007008527A2 (en) | 2007-01-18 |
| CA2613970C (en) | 2015-12-08 |
| CA2613970A1 (en) | 2007-01-18 |
| EP2298794A2 (en) | 2011-03-23 |
| JP2009500037A (ja) | 2009-01-08 |
| US8263363B2 (en) | 2012-09-11 |
| US7811591B2 (en) | 2010-10-12 |
| US20110081357A1 (en) | 2011-04-07 |
| US20080311110A1 (en) | 2008-12-18 |
| EP2298794A3 (en) | 2011-04-06 |
| WO2007008527A3 (en) | 2007-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |