ATE487478T1 - Herstellung eines neuen pharmazeutisch geeigneten losartan-salzes und von seinen formen mittels neuer reinigungs- und isolationsverfahren - Google Patents

Herstellung eines neuen pharmazeutisch geeigneten losartan-salzes und von seinen formen mittels neuer reinigungs- und isolationsverfahren

Info

Publication number
ATE487478T1
ATE487478T1 AT04706411T AT04706411T ATE487478T1 AT E487478 T1 ATE487478 T1 AT E487478T1 AT 04706411 T AT04706411 T AT 04706411T AT 04706411 T AT04706411 T AT 04706411T AT E487478 T1 ATE487478 T1 AT E487478T1
Authority
AT
Austria
Prior art keywords
new
production
forms
purification
isolation methods
Prior art date
Application number
AT04706411T
Other languages
English (en)
Inventor
Ljubomir Antoncic
Anton Copar
Peter Svete
Breda Husu-Kovacecic
Zoran Ham
Boris Marolt
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SI200300026A external-priority patent/SI21424A/sl
Priority claimed from SI200300025A external-priority patent/SI21423A/sl
Priority claimed from SI200300145A external-priority patent/SI21508A/sl
Priority claimed from SI200300157A external-priority patent/SI21509A/sl
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Application granted granted Critical
Publication of ATE487478T1 publication Critical patent/ATE487478T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT04706411T 2003-01-30 2004-01-29 Herstellung eines neuen pharmazeutisch geeigneten losartan-salzes und von seinen formen mittels neuer reinigungs- und isolationsverfahren ATE487478T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SI200300026A SI21424A (sl) 2003-01-30 2003-01-30 Postopek čiščenja losartana
SI200300025A SI21423A (sl) 2003-01-30 2003-01-30 Priprava novih farmacevtsko uporabnih oblik losartana z novimi metodami čiščenja in izolacije
SI200300145A SI21508A (sl) 2003-06-12 2003-06-12 Proces priprave tetrazolskih derivatov v novi kristalni obliki
SI200300157A SI21509A (sl) 2003-06-26 2003-06-26 Priprava tetrazolskega derivata v novi kristalni obliki
SI200300270 2003-11-05
PCT/SI2004/000001 WO2004066997A2 (en) 2003-01-30 2004-01-29 Preparation of new pharmaceutically suitable salt of losartan and forms thereof with new purification and isolation methods

Publications (1)

Publication Number Publication Date
ATE487478T1 true ATE487478T1 (de) 2010-11-15

Family

ID=32831169

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04706411T ATE487478T1 (de) 2003-01-30 2004-01-29 Herstellung eines neuen pharmazeutisch geeigneten losartan-salzes und von seinen formen mittels neuer reinigungs- und isolationsverfahren

Country Status (6)

Country Link
US (1) US7271269B2 (de)
EP (1) EP1589966B1 (de)
AT (1) ATE487478T1 (de)
DE (1) DE602004029982D1 (de)
SI (1) SI1589966T1 (de)
WO (1) WO2004066997A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20032472A1 (it) * 2003-12-16 2005-06-17 Dinamite Dipharma S P A In Forma A Bbreviata Diph Procedimento per la preparazione di losartan potassio cristallino
EP1729766A1 (de) * 2004-03-01 2006-12-13 LEK Pharmaceuticals D.D. Pharmazeutische formulierung
ITMI20050551A1 (it) * 2005-04-01 2006-10-02 Dipharma Spa Forma cristallina alfa di losartan potassio
EP1906936A2 (de) * 2005-05-18 2008-04-09 Combino Pharm, S.L. Formulierungen mit losartan und/oder dessen salzen
WO2007049292A1 (en) * 2005-10-27 2007-05-03 Lupin Limited Pharmaceutical formulation of losartan
DE602005024726D1 (de) * 2005-12-01 2010-12-23 Ulkar Kimya Sanayii Ve Ticaret Artan
WO2008018843A1 (en) * 2006-08-08 2008-02-14 Ulkar Kimya Sanayi Ve Ticaret As Process for producing useful salts form of biphenyl-tetrazole compounds
PE20081200A1 (es) 2006-12-04 2008-11-06 Bayer Schering Pharma Ag Sal de potasio cristalina de analogos de lipoxina a4
WO2013132511A1 (en) * 2012-03-09 2013-09-12 Hetero Research Foundation Novel polymorph of lurasidone hydrochloride

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE395341T1 (de) * 1991-11-18 2008-05-15 Du Pont 2-(2'-triphenylmethyl-2'h-tetrazol-5'- yl)phenylborsäure als zwischenprodukt zur synthese von a ii receptorenantagonisten
GB9406573D0 (en) 1994-03-31 1994-05-25 Merck Sharp & Dohme Medicaments
SE9502219D0 (sv) * 1995-06-19 1995-06-19 Astra Ab Novel medical use
CZ291672B6 (cs) * 1996-10-29 2003-04-16 Merck And Co., Inc. Způsob krystalizace draselné soli losartanu
US5795904A (en) 1996-12-06 1998-08-18 Merck & Co., Inc. Enhanced functional recovery of the heart by losartan treatment after an ischemic attach
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
EP1438027A1 (de) * 2001-10-25 2004-07-21 DepoMed, Inc. Behandlungsmethode unter verwendung einer losartan enthaltenden darreichungsform mit verlängerter magenverweilzeit
US20040097568A1 (en) * 2002-07-29 2004-05-20 Dr. Reddy's Laboratories Limited Crystalline form of losartan potassium

Also Published As

Publication number Publication date
WO2004066997A3 (en) 2004-11-11
US20060004207A1 (en) 2006-01-05
EP1589966B1 (de) 2010-11-10
US7271269B2 (en) 2007-09-18
WO2004066997A2 (en) 2004-08-12
EP1589966A2 (de) 2005-11-02
SI1589966T1 (sl) 2011-06-30
DE602004029982D1 (de) 2010-12-23

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