ATE483972T1 - Reagenzien und verfahren für krebsprognose und pathologische einstufung - Google Patents
Reagenzien und verfahren für krebsprognose und pathologische einstufungInfo
- Publication number
- ATE483972T1 ATE483972T1 AT07757161T AT07757161T ATE483972T1 AT E483972 T1 ATE483972 T1 AT E483972T1 AT 07757161 T AT07757161 T AT 07757161T AT 07757161 T AT07757161 T AT 07757161T AT E483972 T1 ATE483972 T1 AT E483972T1
- Authority
- AT
- Austria
- Prior art keywords
- reagents
- methods
- cancer prognosis
- pathological grading
- grading
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 230000001575 pathological effect Effects 0.000 title 1
- 238000004393 prognosis Methods 0.000 title 1
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77456306P | 2006-02-16 | 2006-02-16 | |
PCT/US2007/062362 WO2007095644A2 (en) | 2006-02-16 | 2007-02-16 | Reagents and methods for cancer prognosis and pathological staging |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE483972T1 true ATE483972T1 (de) | 2010-10-15 |
Family
ID=38335516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07757161T ATE483972T1 (de) | 2006-02-16 | 2007-02-16 | Reagenzien und verfahren für krebsprognose und pathologische einstufung |
Country Status (10)
Country | Link |
---|---|
US (2) | US20070207489A1 (de) |
EP (2) | EP2290361A1 (de) |
JP (1) | JP5143026B2 (de) |
CN (2) | CN101384901A (de) |
AT (1) | ATE483972T1 (de) |
AU (1) | AU2007214427B2 (de) |
CA (1) | CA2642542C (de) |
DE (1) | DE602007009645D1 (de) |
ES (1) | ES2354181T3 (de) |
WO (1) | WO2007095644A2 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007137187A2 (en) | 2006-05-18 | 2007-11-29 | Molecular Profiling Institute, Inc. | System and method for determining individualized medical intervention for a disease state |
US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
US9697582B2 (en) | 2006-11-16 | 2017-07-04 | Visiopharm A/S | Methods for obtaining and analyzing images |
DK2156370T3 (da) | 2007-05-14 | 2012-01-23 | Historx Inc | Kompartmentadskillelse ved pixelkarakterisering under anvendelse af billeddata-clustering |
EP2162728B1 (de) | 2007-06-15 | 2016-07-27 | Novartis AG | Mikroskopisches system und verfahren zur erfassung von standardisierten daten |
CA2604317C (en) | 2007-08-06 | 2017-02-28 | Historx, Inc. | Methods and system for validating sample images for quantitative immunoassays |
CA2596204C (en) | 2007-08-07 | 2019-02-26 | Historx, Inc. | Method and system for determining an optimal dilution of a reagent |
WO2009029810A1 (en) | 2007-08-31 | 2009-03-05 | Historx, Inc. | Automatic exposure time selection for imaging tissue |
EP2327040B1 (de) | 2008-08-15 | 2013-12-18 | Visiopharm A/s | Verfahren und system zum bestimmen eines ziels in einer biologischen probe durch bildanalyse |
US8583380B2 (en) | 2008-09-05 | 2013-11-12 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
ES2573945T3 (es) | 2008-09-16 | 2016-06-13 | Novartis Ag | Cuantificación reproducible de expresión de biomarcadores |
GB2463401B (en) | 2008-11-12 | 2014-01-29 | Caris Life Sciences Luxembourg Holdings S A R L | Characterizing prostate disorders by analysis of microvesicles |
US20120003664A1 (en) * | 2008-12-09 | 2012-01-05 | Uffe Lovborg | Method for evaluating pre-treatment |
WO2010083252A2 (en) | 2009-01-14 | 2010-07-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Ratio based biomarkers and methods of use thereof |
CA2791905A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Biomarkers for theranostics |
AU2011237669B2 (en) | 2010-04-06 | 2016-09-08 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for disease |
MX2012012736A (es) * | 2010-05-07 | 2013-02-26 | Hoffmann La Roche | Metodo de diagnostico para la deteccion de celulas ex vivo. |
CN101876659B (zh) * | 2010-06-29 | 2013-02-13 | 同济大学 | 用于检测肿瘤的量子点试剂盒 |
US9309556B2 (en) | 2010-09-24 | 2016-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Direct capture, amplification and sequencing of target DNA using immobilized primers |
US9410207B2 (en) | 2011-12-30 | 2016-08-09 | Abbott Molecular Inc. | Method and compositions for detecting epidermal growth factor receptor variant forms in cancer cells |
EP3100054B1 (de) * | 2014-01-28 | 2022-02-23 | Quest Diagnostics Investments Incorporated | Verfahren und zusammensetzungen zum nachweis eines adenoma-adenokarzinom-übergangs bei krebs |
CN103882139B (zh) * | 2014-04-04 | 2015-06-03 | 上海赛安生物医药科技有限公司 | 一种用于化疗方案选择的多重基因检测试剂盒 |
EP3249401B1 (de) | 2015-01-22 | 2019-12-25 | Konica Minolta, Inc. | Quantifizierungsverfahren für biologische substanz, pathologisches diagnoseunterstützungssystem und programm |
CN107688092B (zh) * | 2017-08-18 | 2020-05-19 | 国家纳米科学中心 | 一种用于癌症患者预后评估的方法 |
JP7025730B2 (ja) | 2018-02-28 | 2022-02-25 | 日東紡績株式会社 | 固定化細胞又はffpe組織切片から抗原性を増強した細胞核を脱離する方法並びにそのための抗原賦活剤及びキット |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4196265A (en) * | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
US6872817B1 (en) | 1986-01-16 | 2005-03-29 | The Regents Of The Univ. Of California | Method of staining target interphase chromosomal DNA |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
US6326148B1 (en) | 1999-07-12 | 2001-12-04 | The Regents Of The University Of California | Detection of copy number changes in colon cancer |
WO2001092338A1 (en) * | 2000-06-01 | 2001-12-06 | The Brigham And Women's Hospital, Inc. | Diagnosis of endometrial precancers |
JP2005516217A (ja) * | 2001-02-16 | 2005-06-02 | イムニベスト・コーポレイション | 循環している癌細胞の急速かつ効果的な単離のための方法および試薬 |
US20030190602A1 (en) * | 2001-03-12 | 2003-10-09 | Monogen, Inc. | Cell-based detection and differentiation of disease states |
US20040132097A1 (en) * | 2002-06-19 | 2004-07-08 | Bacus Sarah S. | Method for predicting response to epidermal growth factor receptor-directed therapy |
EP2277867B1 (de) * | 2002-07-15 | 2012-12-05 | Symphony Evolution, Inc. | Verbindungen, pharmazeutische Zusammensetzungen die diese enthalten und ihre Verwendung zur Behandlung von Krebs |
US20040106141A1 (en) * | 2002-11-05 | 2004-06-03 | The Regents Of The University Of California | Methods and materials for examining pathways associated with glioblastoma progression |
WO2004111273A2 (en) * | 2003-05-30 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for response to egfr inhibitor drugs |
DE10345021A1 (de) * | 2003-09-23 | 2005-05-04 | Univ Potsdam | Verfahren zur nichtinvasiven Früherkennung von Dickdarmkrebs und/oder Darmkrebsvorläuferzellen |
US9086403B2 (en) * | 2004-06-03 | 2015-07-21 | The Johns Hopkins University | Methods of screening for cell proliferation or neoplastic disorders |
EP1766068A4 (de) * | 2004-06-04 | 2010-03-03 | Genentech Inc | Egfr-mutationen |
EP1812864A2 (de) * | 2004-10-07 | 2007-08-01 | Emory University | Multifunktionale nanopartikelkonjugate und ihre verwendung |
EP2473495A1 (de) * | 2009-09-18 | 2012-07-11 | Almac Discovery Limited | Pharmazeutische verbindungen |
-
2007
- 2007-02-16 JP JP2008555532A patent/JP5143026B2/ja not_active Expired - Fee Related
- 2007-02-16 AT AT07757161T patent/ATE483972T1/de not_active IP Right Cessation
- 2007-02-16 EP EP10012955A patent/EP2290361A1/de not_active Withdrawn
- 2007-02-16 ES ES07757161T patent/ES2354181T3/es active Active
- 2007-02-16 EP EP07757161A patent/EP1984735B1/de not_active Not-in-force
- 2007-02-16 AU AU2007214427A patent/AU2007214427B2/en not_active Ceased
- 2007-02-16 US US11/707,691 patent/US20070207489A1/en not_active Abandoned
- 2007-02-16 CN CNA2007800057525A patent/CN101384901A/zh active Pending
- 2007-02-16 DE DE602007009645T patent/DE602007009645D1/de active Active
- 2007-02-16 CN CN201510119060.XA patent/CN104749378A/zh active Pending
- 2007-02-16 WO PCT/US2007/062362 patent/WO2007095644A2/en active Application Filing
- 2007-02-16 CA CA2642542A patent/CA2642542C/en not_active Expired - Fee Related
-
2010
- 2010-01-19 US US12/690,008 patent/US20100184099A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2642542A1 (en) | 2007-08-23 |
JP5143026B2 (ja) | 2013-02-13 |
CA2642542C (en) | 2012-09-25 |
EP2290361A1 (de) | 2011-03-02 |
WO2007095644A2 (en) | 2007-08-23 |
US20100184099A1 (en) | 2010-07-22 |
CN101384901A (zh) | 2009-03-11 |
US20070207489A1 (en) | 2007-09-06 |
EP1984735B1 (de) | 2010-10-06 |
EP1984735A2 (de) | 2008-10-29 |
AU2007214427A1 (en) | 2007-08-23 |
ES2354181T3 (es) | 2011-03-10 |
CN104749378A (zh) | 2015-07-01 |
WO2007095644A3 (en) | 2007-12-27 |
JP2009527740A (ja) | 2009-07-30 |
AU2007214427B2 (en) | 2011-11-10 |
DE602007009645D1 (de) | 2010-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |