ATE482231T1 - Anhydrothrombinderivate und verfahren zu deren herstellung, die blutplättchenagglutination induzierende zusammensetzungen, verfahren zur induktion der blutplättchenagglutination, klinische testreagenzien, klinisches testverfahren, thromboseinhibitoren, adsorbens und verfahren - Google Patents
Anhydrothrombinderivate und verfahren zu deren herstellung, die blutplättchenagglutination induzierende zusammensetzungen, verfahren zur induktion der blutplättchenagglutination, klinische testreagenzien, klinisches testverfahren, thromboseinhibitoren, adsorbens und verfahrenInfo
- Publication number
- ATE482231T1 ATE482231T1 AT02705334T AT02705334T ATE482231T1 AT E482231 T1 ATE482231 T1 AT E482231T1 AT 02705334 T AT02705334 T AT 02705334T AT 02705334 T AT02705334 T AT 02705334T AT E482231 T1 ATE482231 T1 AT E482231T1
- Authority
- AT
- Austria
- Prior art keywords
- agglutination
- methods
- anhydrothrombin
- clinical test
- inducing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001079469 | 2001-03-19 | ||
| PCT/JP2002/002594 WO2002077031A1 (en) | 2001-03-19 | 2002-03-19 | Thrombin derivatives and process for producing the same, anhydrothrombin derivatives and process for producing the same, platelet agglutination-inducing compositions, method of inducing platelet agglutination, clinical test reagents, clinical test method, thrombosis inhibitors, adsorbent and process for producing the same, |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482231T1 true ATE482231T1 (de) | 2010-10-15 |
Family
ID=18935915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02705334T ATE482231T1 (de) | 2001-03-19 | 2002-03-19 | Anhydrothrombinderivate und verfahren zu deren herstellung, die blutplättchenagglutination induzierende zusammensetzungen, verfahren zur induktion der blutplättchenagglutination, klinische testreagenzien, klinisches testverfahren, thromboseinhibitoren, adsorbens und verfahren |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6946279B2 (de) |
| EP (1) | EP1371663B1 (de) |
| JP (1) | JP4137642B2 (de) |
| KR (1) | KR100863078B1 (de) |
| CN (1) | CN1281624C (de) |
| AT (1) | ATE482231T1 (de) |
| AU (1) | AU2002238965B8 (de) |
| CA (1) | CA2441201A1 (de) |
| DE (1) | DE60237757D1 (de) |
| WO (1) | WO2002077031A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060133031A (ko) * | 2004-03-19 | 2006-12-22 | 칫소가부시키가이샤 | 트롬빈 유도체 및 그것을 포함하는 의약 조성물 |
| CN114958963B (zh) * | 2022-07-29 | 2023-09-05 | 深圳传世生物医疗有限公司 | 一种作用于凝血酶的抗凝药物检测试剂盒及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59408292D1 (de) * | 1993-02-19 | 1999-07-01 | Hoffmann La Roche | Racemisierungsfreie Herstellung von Amiden und Peptiden in Gegenwart katalytischer Mengen einer N-Hydroxy-Verbindung |
| FR2701951B1 (fr) | 1993-02-24 | 1995-06-09 | Adir | Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| JPH1149800A (ja) * | 1997-06-05 | 1999-02-23 | Fujimori Kogyo Kk | アンヒドロトロンビンの合成方法 |
| EP0882789A3 (de) * | 1997-06-05 | 2001-09-26 | Fujimori Kogyo Co., Ltd. | Verfahren für die Synthese von Anhydrothrombin |
| AU5709500A (en) | 1999-07-08 | 2001-01-30 | Fujimori Kogyo Co. Ltd. | Serine protease inhibitor |
-
2002
- 2002-03-19 WO PCT/JP2002/002594 patent/WO2002077031A1/ja not_active Ceased
- 2002-03-19 AU AU2002238965A patent/AU2002238965B8/en not_active Ceased
- 2002-03-19 EP EP02705334A patent/EP1371663B1/de not_active Expired - Lifetime
- 2002-03-19 DE DE60237757T patent/DE60237757D1/de not_active Expired - Lifetime
- 2002-03-19 JP JP2002576289A patent/JP4137642B2/ja not_active Expired - Fee Related
- 2002-03-19 US US10/472,237 patent/US6946279B2/en not_active Expired - Fee Related
- 2002-03-19 KR KR1020037011791A patent/KR100863078B1/ko not_active Expired - Fee Related
- 2002-03-19 CN CNB028067908A patent/CN1281624C/zh not_active Expired - Fee Related
- 2002-03-19 CA CA002441201A patent/CA2441201A1/en not_active Abandoned
- 2002-03-19 AT AT02705334T patent/ATE482231T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60237757D1 (de) | 2010-11-04 |
| WO2002077031A1 (en) | 2002-10-03 |
| EP1371663A1 (de) | 2003-12-17 |
| AU2002238965B8 (en) | 2007-05-17 |
| EP1371663A4 (de) | 2004-09-15 |
| AU2002238965A1 (en) | 2002-10-08 |
| CN1498226A (zh) | 2004-05-19 |
| KR20030088451A (ko) | 2003-11-19 |
| EP1371663B1 (de) | 2010-09-22 |
| JP4137642B2 (ja) | 2008-08-20 |
| KR100863078B1 (ko) | 2008-10-10 |
| US6946279B2 (en) | 2005-09-20 |
| CA2441201A1 (en) | 2002-10-03 |
| JPWO2002077031A1 (ja) | 2004-07-15 |
| AU2002238965B2 (en) | 2007-04-19 |
| CN1281624C (zh) | 2006-10-25 |
| US20040096953A1 (en) | 2004-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |