ATE476972T1 - Verwendung von valproinsäure zur topischen behandlung von leichter bis mittelschwerer akne vulgaris - Google Patents
Verwendung von valproinsäure zur topischen behandlung von leichter bis mittelschwerer akne vulgarisInfo
- Publication number
- ATE476972T1 ATE476972T1 AT07711939T AT07711939T ATE476972T1 AT E476972 T1 ATE476972 T1 AT E476972T1 AT 07711939 T AT07711939 T AT 07711939T AT 07711939 T AT07711939 T AT 07711939T AT E476972 T1 ATE476972 T1 AT E476972T1
- Authority
- AT
- Austria
- Prior art keywords
- vpa
- acne vulgaris
- mild
- valproic acid
- topical treatment
- Prior art date
Links
- NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical compound CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 title abstract 8
- 230000000699 topical effect Effects 0.000 title abstract 4
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract 3
- 206010000496 acne Diseases 0.000 title abstract 3
- 229960000604 valproic acid Drugs 0.000 title abstract 2
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960005280 isotretinoin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000009097 single-agent therapy Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06006847A EP1839656A1 (en) | 2006-03-31 | 2006-03-31 | Use of valproic acid for the topical treatment of mild to moderate acne vulgaris |
| PCT/EP2007/002201 WO2007112832A1 (en) | 2006-03-31 | 2007-03-13 | Use of valproic acid for the topical treatment of mild to moderate acne vulgaris |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476972T1 true ATE476972T1 (de) | 2010-08-15 |
Family
ID=36498743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07711939T ATE476972T1 (de) | 2006-03-31 | 2007-03-13 | Verwendung von valproinsäure zur topischen behandlung von leichter bis mittelschwerer akne vulgaris |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090186809A1 (enExample) |
| EP (2) | EP1839656A1 (enExample) |
| JP (1) | JP2009534306A (enExample) |
| AT (1) | ATE476972T1 (enExample) |
| DE (1) | DE602007008385D1 (enExample) |
| WO (1) | WO2007112832A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492438B2 (en) * | 2002-04-26 | 2013-07-23 | Asan Laboratories Company (Cayman), Limited | Treatment skin disorders |
| EP1491188A1 (en) * | 2003-06-25 | 2004-12-29 | G2M Cancer Drugs AG | Topical use of valproic acid for the prevention or treatment of skin disorders |
| CA2596210C (en) | 2005-02-03 | 2014-07-08 | Topotarget Uk Limited | Combination therapies using hdac inhibitors |
| ES2380887T3 (es) | 2005-05-13 | 2012-05-21 | Topotarget Uk Limited | Formulaciones farmacéuticas de inhibidores de la HDAC |
| US8828392B2 (en) * | 2005-11-10 | 2014-09-09 | Topotarget Uk Limited | Histone deacetylase (HDAC) inhibitors (PXD101) for the treatment of cancer alone or in combination with chemotherapeutic agent |
| EP2203421B1 (en) * | 2007-09-25 | 2014-05-07 | TopoTarget UK Limited | Methods of synthesis of certain n-hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamide compounds |
| US20110003777A1 (en) * | 2008-03-07 | 2011-01-06 | Topotarget A/S | Methods of Treatment Employing Prolonged Continuous Infusion of Belinostat |
| EP2367563A4 (en) | 2008-12-08 | 2012-12-19 | Univ Northwestern | PROCESS FOR HSF-1 MODULATION |
| GB0900555D0 (en) * | 2009-01-14 | 2009-02-11 | Topotarget As | New methods |
| AU2011213694B2 (en) * | 2010-02-05 | 2014-05-29 | Sunny Pharmtech, Inc. | Treatment skin disorders |
| KR101733189B1 (ko) | 2010-10-06 | 2017-05-08 | (주)아모레퍼시픽 | 손톱 또는 발톱 성장 촉진용 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1491188A1 (en) * | 2003-06-25 | 2004-12-29 | G2M Cancer Drugs AG | Topical use of valproic acid for the prevention or treatment of skin disorders |
| EP1591109B1 (en) * | 2004-04-30 | 2008-07-02 | TopoTarget Germany AG | Formulation comprising histone deacetylase inhibitor exhibiting biphasic release |
| JP5279268B2 (ja) * | 2004-07-28 | 2013-09-04 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ヒストンデアセチラーゼの新規な阻害剤としての置換されたプロペニルピペラジン誘導体 |
-
2006
- 2006-03-31 EP EP06006847A patent/EP1839656A1/en not_active Withdrawn
-
2007
- 2007-03-13 US US12/295,359 patent/US20090186809A1/en not_active Abandoned
- 2007-03-13 WO PCT/EP2007/002201 patent/WO2007112832A1/en not_active Ceased
- 2007-03-13 EP EP07711939A patent/EP2001458B1/en not_active Not-in-force
- 2007-03-13 DE DE602007008385T patent/DE602007008385D1/de active Active
- 2007-03-13 AT AT07711939T patent/ATE476972T1/de not_active IP Right Cessation
- 2007-03-13 JP JP2009501893A patent/JP2009534306A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2001458A1 (en) | 2008-12-17 |
| WO2007112832A1 (en) | 2007-10-11 |
| DE602007008385D1 (de) | 2010-09-23 |
| JP2009534306A (ja) | 2009-09-24 |
| EP2001458B1 (en) | 2010-08-11 |
| US20090186809A1 (en) | 2009-07-23 |
| EP1839656A1 (en) | 2007-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |