ATE474062T1 - Tests zur bestimmung tram-phosphorylierung modulierender verbindungen - Google Patents

Tests zur bestimmung tram-phosphorylierung modulierender verbindungen

Info

Publication number
ATE474062T1
ATE474062T1 AT06728129T AT06728129T ATE474062T1 AT E474062 T1 ATE474062 T1 AT E474062T1 AT 06728129 T AT06728129 T AT 06728129T AT 06728129 T AT06728129 T AT 06728129T AT E474062 T1 ATE474062 T1 AT E474062T1
Authority
AT
Austria
Prior art keywords
tram
phosphorylation
tests
modulating compounds
modulating
Prior art date
Application number
AT06728129T
Other languages
English (en)
Inventor
Luke O'neill
Anne Mcgettrick
Original Assignee
Trinity College Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0506768A external-priority patent/GB0506768D0/en
Priority claimed from GB0521325A external-priority patent/GB0521325D0/en
Application filed by Trinity College Dublin filed Critical Trinity College Dublin
Application granted granted Critical
Publication of ATE474062T1 publication Critical patent/ATE474062T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT06728129T 2005-04-02 2006-04-03 Tests zur bestimmung tram-phosphorylierung modulierender verbindungen ATE474062T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0506768A GB0506768D0 (en) 2005-04-02 2005-04-02 Assays relating to toll-like receptor 4 activity and compositions for modulating the same
US67482805P 2005-04-26 2005-04-26
GB0521325A GB0521325D0 (en) 2005-10-20 2005-10-20 Assays relating to toll-like receptor 4 activity and compositions for modulating the same
PCT/IE2006/000023 WO2006106492A2 (en) 2005-04-02 2006-04-03 Assays for determining compounds which modulate tram phosphorylation

Publications (1)

Publication Number Publication Date
ATE474062T1 true ATE474062T1 (de) 2010-07-15

Family

ID=37073841

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06728129T ATE474062T1 (de) 2005-04-02 2006-04-03 Tests zur bestimmung tram-phosphorylierung modulierender verbindungen

Country Status (8)

Country Link
US (1) US8221992B2 (de)
EP (1) EP1869205B1 (de)
JP (2) JP2008537880A (de)
AT (1) ATE474062T1 (de)
AU (1) AU2006231724B2 (de)
CA (1) CA2603868A1 (de)
DE (1) DE602006015451D1 (de)
WO (1) WO2006106492A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0620705D0 (en) * 2006-10-18 2006-11-29 Opsona Therapeutics Compounds for the modulation of toll-like receptor activity and assay methods for the identification of said compounds
CN102507707B (zh) * 2011-10-12 2015-10-21 山东大学 一种检测龈沟液中蛋白裂解酶含量的方法
JP2014117191A (ja) * 2012-12-13 2014-06-30 Fisheries Research Agency リン酸化中性スフィンゴミエリナーゼ１、抗リン酸化中性スフィンゴミエリナーゼ１抗体、中性スフィンゴミエリナーゼ１変異体、及びそれらの用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE350032T1 (de) * 1998-07-06 2007-01-15 Univ California Verwendung der protein-kinase-c-epsilon- inhibitoren zur behandlung von schmerzen
JP4230294B2 (ja) 2003-06-30 2009-02-25 独立行政法人科学技術振興機構 哺乳動物のＴｏｌｌ様受容体４に結合しタイプＩインターフェロン誘導を媒介する新規アダプター分子およびその利用
JP4236549B2 (ja) 2003-09-29 2009-03-11 独立行政法人科学技術振興機構 エンドトキシン不応答性モデル動物
US20060004043A1 (en) * 2003-11-19 2006-01-05 Bhagwat Shripad S Indazole compounds and methods of use thereof

Also Published As

Publication number Publication date
JP2012157358A (ja) 2012-08-23
WO2006106492A2 (en) 2006-10-12
AU2006231724A1 (en) 2006-10-12
AU2006231724B2 (en) 2012-04-26
WO2006106492A3 (en) 2007-02-01
DE602006015451D1 (de) 2010-08-26
JP2008537880A (ja) 2008-10-02
US8221992B2 (en) 2012-07-17
US20090123482A1 (en) 2009-05-14
EP1869205A2 (de) 2007-12-26
CA2603868A1 (en) 2006-10-12
EP1869205B1 (de) 2010-07-14

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