ATE473801T1 - Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte - Google Patents

Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte

Info

Publication number
ATE473801T1
ATE473801T1 AT05749421T AT05749421T ATE473801T1 AT E473801 T1 ATE473801 T1 AT E473801T1 AT 05749421 T AT05749421 T AT 05749421T AT 05749421 T AT05749421 T AT 05749421T AT E473801 T1 ATE473801 T1 AT E473801T1
Authority
AT
Austria
Prior art keywords
liquid
fluid
microblades
injecting
producing
Prior art date
Application number
AT05749421T
Other languages
English (en)
Inventor
Jeroen Mathijn Wissink
Rijn Cornelis Johannes Maria Van
Wietze Nijdam
Christiaan Goeting
Iwan Rutger Heskamp
Gerrit Jan Veldhuis
Original Assignee
Nanomi B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanomi B V filed Critical Nanomi B V
Application granted granted Critical
Publication of ATE473801T1 publication Critical patent/ATE473801T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B01F25/31421—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction the conduit being porous
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B01F25/31425—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction with a plurality of perforations in the axial and circumferential direction covering the whole surface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0427—Numerical distance values, e.g. separation, position
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0357—For producing uniform flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/212—System comprising plural fluidic devices or stages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Nozzles (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT05749421T 2004-05-25 2005-05-25 Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte ATE473801T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1026261A NL1026261C2 (nl) 2004-05-25 2004-05-25 Sproei inrichting met een nozzleplaat voorzien van structuren ter bevordering van self-breakup, een nozzleplaat, alsmede werkwijzen ter vervaardiging en toepassing van een dergelijke nozzleplaat.
PCT/NL2005/000385 WO2005115599A1 (en) 2004-05-25 2005-05-25 Device for generating microspheres from a fluid, method of injecting at least one first fluid into a second fluid, and an injection plate

Publications (1)

Publication Number Publication Date
ATE473801T1 true ATE473801T1 (de) 2010-07-15

Family

ID=34969103

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05749421T ATE473801T1 (de) 2004-05-25 2005-05-25 Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte

Country Status (9)

Country Link
US (1) US8100348B2 (de)
EP (1) EP1755773B1 (de)
CN (1) CN100563806C (de)
AT (1) ATE473801T1 (de)
DE (1) DE602005022309D1 (de)
DK (1) DK1755773T3 (de)
ES (1) ES2348954T3 (de)
NL (1) NL1026261C2 (de)
WO (1) WO2005115599A1 (de)

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NL1016030C1 (nl) 2000-08-28 2002-03-01 Aquamarijn Holding B V Sproei inrichting met een nozzleplaat, een nozzleplaat, alsmede werkwijzen ter vervaardiging en voor toepassing van een dergelijke nozzleplaat.
US8181941B2 (en) * 2006-03-04 2012-05-22 Hce, Llc Gas bubble storage
US20090023189A1 (en) * 2007-05-18 2009-01-22 Applera Corporation Apparatus and methods for preparation of subtantially uniform emulsions containing a particle
CN102124259B (zh) 2008-05-16 2015-12-16 哈佛大学 在包含微流体系统的流体系统中的阀和其它流动控制
EP2435461B1 (de) 2009-05-29 2017-08-09 Life Technologies Corporation Nukleinsäuregerüst-polymerpartikel und verfahren zu ihrer herstellung und verwendung
PL2859887T3 (pl) 2010-07-09 2017-10-31 Innocore Tech B V Biodegradowalne segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów
CA2841430C (en) 2011-03-30 2018-12-04 Gnubio, Inc. Injection of multiple volumes into or out of droplets
CN103946712A (zh) * 2011-09-30 2014-07-23 不列颠哥伦比亚大学 用于流动控制润湿的方法和设备
EP2948703B1 (de) * 2013-01-25 2019-03-13 Bio-Rad Laboratories, Inc. System und verfahren zur durchführung einer tropfeninflation
US9907876B2 (en) 2013-04-22 2018-03-06 The Regents Of The University Of California Switchable gas and liquid release and delivery devices, systems, and methods
USD732093S1 (en) * 2014-03-19 2015-06-16 Veeco Ald Inc. Gas tube assembly
USD732092S1 (en) * 2014-03-19 2015-06-16 Veeco Ald Inc. Gas injection plate
US11406742B2 (en) 2014-07-18 2022-08-09 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US9492594B2 (en) 2014-07-18 2016-11-15 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
EP3000528B1 (de) * 2014-09-25 2020-12-16 European Molecular Biology Laboratory Mikrofluidische vorrichtung zur erzeugung von kombinatorischen proben
EP3280541B1 (de) 2015-04-10 2025-12-03 The Regents of The University of California Digital steuerbare vorrichtung zur erzeugung und abgabe von düften
EP3352735B1 (de) 2015-09-21 2023-08-30 Teva Pharmaceuticals International GmbH Olanzapinformulierungen mit verzögerter freisetzung
AU2018238136A1 (en) 2017-03-20 2019-11-07 Teva Pharmaceuticals International Gmbh Sustained release olanzapine formulations
CN110799178A (zh) 2017-04-19 2020-02-14 纳诺米有限公司 用于制备基本上单分散的物质的颗粒的方法和系统
EP3687503A1 (de) 2017-09-26 2020-08-05 Nanomi B.V. Verfahren zur herstellung von mikropartikeln durch doppelemulsionstechnik
AU2019362775B2 (en) 2018-10-15 2025-09-25 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US20200376128A1 (en) 2019-06-01 2020-12-03 Lupin Holdings B.V. Monodisperse resorbable polyester polymer compositions, systems, and methods
WO2021013861A1 (en) 2019-07-22 2021-01-28 Nanomi, B.V. Sustained release trepostinil-compound microparticle compositions
CN112495300B (zh) * 2020-11-10 2022-02-01 清华大学 微喷嘴阵列膜及微液滴生成装置
EP4277661A1 (de) 2021-01-18 2023-11-22 Anton Frenkel Pharmazeutische darreichungsform
CN118284414A (zh) 2021-07-06 2024-07-02 M·哈斯莱顿 血清素再摄取抑制剂戒断综合征的治疗
CN116036951B (zh) * 2021-10-28 2024-09-20 中国石油天然气股份有限公司 一种数字化配药调剖集成装置及其操作方法
AU2023355823A1 (en) 2022-10-05 2025-04-17 Mireca Medicines Gmbh MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY

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DE2538190C3 (de) * 1975-08-27 1985-04-04 Rumpf, geb. Strupp, Lieselotte Clara, 7500 Karlsruhe Verfahren und Vorrichtung zur kontinuierlichen Fliehkraftsichtung eines stetigen Mengenstroms von körnigem Gut
JPS59145079A (ja) * 1983-02-08 1984-08-20 日鉄鉱業株式会社 粉体粒子の風力分級装置
US4657667A (en) * 1984-04-05 1987-04-14 The University Of Toronto Innovations Foundation Particle classifier
SU1296205A1 (ru) * 1984-12-29 1987-03-15 Дальневосточное высшее инженерное морское училище им.адм.Г.И.Невельского Способ приготовлени водотопливных эмульсий
JPH0619586B2 (ja) * 1986-05-12 1994-03-16 キヤノン株式会社 静電荷像現像用トナ−の製造方法
JP3123153B2 (ja) * 1991-11-11 2001-01-09 ミノルタ株式会社 静電荷像現像用トナーおよびその製造方法
JP3511238B2 (ja) 2000-10-13 2004-03-29 独立行政法人食品総合研究所 マイクロスフィアの製造方法および製造装置
JP2006507921A (ja) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置

Also Published As

Publication number Publication date
EP1755773A1 (de) 2007-02-28
CN100563806C (zh) 2009-12-02
ES2348954T3 (es) 2010-12-17
EP1755773B1 (de) 2010-07-14
DE602005022309D1 (de) 2010-08-26
WO2005115599A1 (en) 2005-12-08
CN1968737A (zh) 2007-05-23
US20070227591A1 (en) 2007-10-04
NL1026261C2 (nl) 2005-11-28
US8100348B2 (en) 2012-01-24
DK1755773T3 (da) 2010-11-01

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