ATE471720T1 - Erhöhung des adenosin-spiegels durch cytokin- induzierte expression von cd73 - Google Patents
Erhöhung des adenosin-spiegels durch cytokin- induzierte expression von cd73Info
- Publication number
- ATE471720T1 ATE471720T1 AT04721913T AT04721913T ATE471720T1 AT E471720 T1 ATE471720 T1 AT E471720T1 AT 04721913 T AT04721913 T AT 04721913T AT 04721913 T AT04721913 T AT 04721913T AT E471720 T1 ATE471720 T1 AT E471720T1
- Authority
- AT
- Austria
- Prior art keywords
- cytokine
- induced expression
- adenosine levels
- increasing adenosine
- increasing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cell Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI20030467A FI20030467A0 (fi) | 2003-03-28 | 2003-03-28 | Menetelmä tulehdustilojen hoitamiseen |
US51542503P | 2003-10-30 | 2003-10-30 | |
PCT/FI2004/000158 WO2004084933A1 (en) | 2003-03-28 | 2004-03-19 | Elevation of adenosine level by cytokine-induced expression of cd73 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE471720T1 true ATE471720T1 (de) | 2010-07-15 |
Family
ID=33099764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04721913T ATE471720T1 (de) | 2003-03-28 | 2004-03-19 | Erhöhung des adenosin-spiegels durch cytokin- induzierte expression von cd73 |
Country Status (9)
Country | Link |
---|---|
US (3) | US7534423B2 (de) |
EP (1) | EP1608400B1 (de) |
JP (1) | JP2011225607A (de) |
AT (1) | ATE471720T1 (de) |
CA (1) | CA2519465C (de) |
CY (1) | CY1111215T1 (de) |
DE (1) | DE602004027797D1 (de) |
PL (1) | PL1608400T3 (de) |
WO (1) | WO2004084933A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070160645A1 (en) * | 2001-10-25 | 2007-07-12 | Jakob Vinten-Johansen | PostConditioning System And Method For The Reduction Of Ischemic-Reperfusion Injury In The Heart And Other Organs |
ES2316618T3 (es) | 2001-10-25 | 2009-04-16 | Emory University | Cateter para perfusion modificada. |
WO2006069170A2 (en) * | 2004-12-22 | 2006-06-29 | Emory University | Therapeutic adjuncts to enhance the organ protective effects of postconditioning |
ATE471720T1 (de) | 2003-03-28 | 2010-07-15 | Faron Pharmaceuticals Oy | Erhöhung des adenosin-spiegels durch cytokin- induzierte expression von cd73 |
FI20051003A0 (fi) | 2005-10-07 | 2005-10-07 | Faron Pharmaceuticals Oy | Menetelmä iskemiareperfuusiovaurion tai monielinhäiriön hoitamiseksi tai estämiseksi |
FI20070795A0 (fi) * | 2007-10-24 | 2007-10-24 | Faron Pharmaceuticals Oy | Uusi biomarkkeri sairauksien kehittämisen tarkkailuun ja terapioiden tehon arviointiin |
US8975081B2 (en) * | 2007-10-24 | 2015-03-10 | Faron Pharmaceuticals Oy | Biomarker for monitoring development of diseases and assessing the efficacy of therapies |
US20090130092A1 (en) | 2007-10-30 | 2009-05-21 | Pinsky David J | Nucleotide phosphate dissipation as a treatment for vascular disorders |
WO2009106368A1 (en) * | 2008-02-29 | 2009-09-03 | Gelato Corporation N.V. | Method for increasing the activity of the immune system of a mammal at risk of inflammatory diseases |
CN102014959B (zh) * | 2008-03-10 | 2016-01-20 | 康奈尔大学 | 血脑屏障通透性的调节 |
IN2012DN02753A (de) | 2009-08-31 | 2015-09-18 | Amplimmune Inc | |
CN107441480A (zh) | 2010-06-30 | 2017-12-08 | 卡姆普根有限公司 | 多肽及其作为用于治疗多发性硬化、类风湿性关节炎以及其他自身免疫病症的药物的用途 |
CU23963B1 (es) * | 2011-07-01 | 2013-12-11 | Ct De Ingeniería Genética Y Biotecnología | Composiciones farmacéuticas a partir de derivados de la c-ficocianina y combinaciones con interferones del tipo i para el tratamiento de enfermedades cerebrales isquémicas y neurodegenerativas |
WO2013040552A2 (en) | 2011-09-16 | 2013-03-21 | Georgia Health Sciences University | Methods of promoting immune tolerance |
WO2013082458A1 (en) | 2011-12-02 | 2013-06-06 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
EP2934575A2 (de) | 2012-12-19 | 2015-10-28 | Amplimmune, Inc. | B7-h4-spezifische antikörper sowie zusammensetzungen und verfahren zur verwendung davon |
ES2957882T3 (es) | 2015-09-04 | 2024-01-29 | Univ Yale | Nanocomposiciones de ácidos biliares poliméricos dirigidas al páncreas y al colon |
FI126979B (en) | 2016-02-29 | 2017-09-15 | Faron Pharmaceuticals Oy | Lyophilized pharmaceutical formulation and use thereof |
WO2017155981A1 (en) | 2016-03-07 | 2017-09-14 | Massachusetts Institute Of Technology | Protein-chaperoned t-cell vaccines |
US20190117799A1 (en) | 2016-04-01 | 2019-04-25 | The Brigham And Women's Hospital, Inc. | Stimuli-responsive nanoparticles for biomedical applications |
RU2757394C2 (ru) | 2016-08-03 | 2021-10-14 | Нексткьюр, Инк. | Композиции и способы для модуляции передачи сигнала lair |
EP4360714A2 (de) | 2016-09-21 | 2024-05-01 | Nextcure, Inc. | Antikörper für siglec-15 und verfahren zur verwendung davon |
US11390675B2 (en) | 2016-09-21 | 2022-07-19 | Nextcure, Inc. | Antibodies for Siglec-15 and methods of use thereof |
AU2018329840A1 (en) | 2017-09-07 | 2020-03-19 | Augusta University Research Institute, Inc. | Specific Akt3 activator and uses thereof |
EP3911302A1 (de) | 2019-01-17 | 2021-11-24 | Georgia Tech Research Corporation | Arzneimittelabgabesysteme mit oxidierten cholesterinen |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341369C (en) * | 1985-10-14 | 2002-06-18 | Michel Revel | Human interferon-.beta.2a and interferon-.beta.2b; vectors containing genes coding for said interferons: cell lines producing same and use of said interferons as pharmaceuticals |
GB9702021D0 (en) * | 1997-01-31 | 1997-03-19 | Imperial College | Medicaments |
EP1221976A4 (de) * | 1999-09-28 | 2003-12-03 | Amarillo Biosciences Inc | Ifn-gama in niedriger dosierung zur behandlung von erkrankungen |
DE60129472T2 (de) | 2001-04-03 | 2008-04-17 | U-Cytech B.V. | Behandlung von hypoxya/ischaemia blutflusswiderstand mit beta-interferon |
WO2002089828A2 (en) | 2001-05-04 | 2002-11-14 | Institute Of Molecular And Cell Biology | Interferons in the treatment of ischemia |
US6911198B2 (en) | 2001-09-17 | 2005-06-28 | Yeda Research And Development Co. Ltd. | Method and pharmaceutical composition for treating inflammation |
WO2003075944A2 (en) | 2002-03-12 | 2003-09-18 | Maxygen Aps | Interferon beta-like molecules for treatment of stroke |
ATE471720T1 (de) | 2003-03-28 | 2010-07-15 | Faron Pharmaceuticals Oy | Erhöhung des adenosin-spiegels durch cytokin- induzierte expression von cd73 |
-
2004
- 2004-03-19 AT AT04721913T patent/ATE471720T1/de active
- 2004-03-19 PL PL04721913T patent/PL1608400T3/pl unknown
- 2004-03-19 CA CA2519465A patent/CA2519465C/en not_active Expired - Lifetime
- 2004-03-19 EP EP04721913A patent/EP1608400B1/de not_active Expired - Lifetime
- 2004-03-19 DE DE602004027797T patent/DE602004027797D1/de not_active Expired - Lifetime
- 2004-03-19 US US10/546,653 patent/US7534423B2/en active Active
- 2004-03-19 WO PCT/FI2004/000158 patent/WO2004084933A1/en active Application Filing
-
2005
- 2005-10-05 US US11/242,937 patent/US7727521B2/en active Active
-
2009
- 2009-04-24 US US12/429,436 patent/US20090269303A1/en not_active Abandoned
-
2010
- 2010-08-17 CY CY20101100758T patent/CY1111215T1/el unknown
-
2011
- 2011-07-22 JP JP2011161110A patent/JP2011225607A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20090269303A1 (en) | 2009-10-29 |
JP2011225607A (ja) | 2011-11-10 |
CA2519465A1 (en) | 2004-10-07 |
PL1608400T3 (pl) | 2010-11-30 |
WO2004084933A1 (en) | 2004-10-07 |
EP1608400A1 (de) | 2005-12-28 |
US7534423B2 (en) | 2009-05-19 |
US20060198821A1 (en) | 2006-09-07 |
US7727521B2 (en) | 2010-06-01 |
CA2519465C (en) | 2016-08-02 |
EP1608400B1 (de) | 2010-06-23 |
DE602004027797D1 (de) | 2010-08-05 |
US20060034801A1 (en) | 2006-02-16 |
CY1111215T1 (el) | 2015-06-11 |
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Legal Events
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