ATE469901T1 - Verfahren zur herstellung 1-substituierter 1h- imidazoä4,5-cüchinolin-4-aminverbindungen und zwischenprodukte dafür - Google Patents
Verfahren zur herstellung 1-substituierter 1h- imidazoä4,5-cüchinolin-4-aminverbindungen und zwischenprodukte dafürInfo
- Publication number
- ATE469901T1 ATE469901T1 AT06708801T AT06708801T ATE469901T1 AT E469901 T1 ATE469901 T1 AT E469901T1 AT 06708801 T AT06708801 T AT 06708801T AT 06708801 T AT06708801 T AT 06708801T AT E469901 T1 ATE469901 T1 AT E469901T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- amine compounds
- imidazoä4
- cuchinolin
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000013067 intermediate product Substances 0.000 title 1
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- HQBUPOAKJGJGCD-UHFFFAOYSA-N 3h-imidazo[4,5-c]quinolin-4-amine Chemical class NC1=NC2=CC=CC=C2C2=C1N=CN2 HQBUPOAKJGJGCD-UHFFFAOYSA-N 0.000 abstract 1
- 150000003948 formamides Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05102229 | 2005-03-21 | ||
| PCT/EP2006/060887 WO2006100226A1 (en) | 2005-03-21 | 2006-03-20 | Method for making 1-substituted 1h-imidazo[4,5-c]quinolin-4-amine compounds and intermediates therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE469901T1 true ATE469901T1 (de) | 2010-06-15 |
Family
ID=36591271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06708801T ATE469901T1 (de) | 2005-03-21 | 2006-03-20 | Verfahren zur herstellung 1-substituierter 1h- imidazoä4,5-cüchinolin-4-aminverbindungen und zwischenprodukte dafür |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8106202B2 (de) |
| EP (1) | EP1879893B1 (de) |
| JP (1) | JP2008533189A (de) |
| KR (1) | KR20070113309A (de) |
| CN (1) | CN101146810A (de) |
| AT (1) | ATE469901T1 (de) |
| AU (1) | AU2006226412A1 (de) |
| BR (1) | BRPI0609399A2 (de) |
| CA (1) | CA2601542C (de) |
| CY (1) | CY1111227T1 (de) |
| DE (1) | DE602006014677D1 (de) |
| DK (1) | DK1879893T3 (de) |
| ES (1) | ES2346687T3 (de) |
| IL (1) | IL186040A (de) |
| MX (1) | MX2007011238A (de) |
| PL (1) | PL1879893T3 (de) |
| PT (1) | PT1879893E (de) |
| RU (1) | RU2007139008A (de) |
| SI (1) | SI1879893T1 (de) |
| WO (1) | WO2006100226A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009504803A (ja) | 2005-08-22 | 2009-02-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Ｔｌｒアゴニスト |
| EP2029597A4 (de) | 2006-05-31 | 2011-11-23 | Univ California | Purinanaloga |
| US7943771B2 (en) * | 2007-01-24 | 2011-05-17 | Chemagis Ltd. | Imiquimod production process |
| ES2456964T3 (es) | 2007-02-07 | 2014-04-24 | The Regents Of The University Of California | Conjugados de agonistas de TLR sintéticos y usos de los mismos |
| US7659398B2 (en) | 2007-02-14 | 2010-02-09 | Chemagis Ltd. | Imiquimod production process |
| WO2010088924A1 (en) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
| WO2010093436A2 (en) | 2009-02-11 | 2010-08-19 | Carson Dennis A | Toll-like receptor modulators and treatment of diseases |
| CA2974153A1 (en) | 2015-02-03 | 2016-08-11 | Trillium Therapeutics Inc. | Fluorinated imidazo[4,5-c]quinoline derivatives as inhibitors of bromodomain containing proteins |
| DK3560924T3 (da) | 2015-04-02 | 2021-06-28 | Merck Patent Gmbh | Imidazolonylquinoliner og deres anvendelse som atm-kinase-inhibitorer |
| US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
| FR3113287B1 (fr) | 2020-08-07 | 2023-06-23 | Phv Pharma | Procédé industriel de synthèse de l’imiquimod à partir de la quinolèine-2,4-diol applicable à son utilisation pharmaceutique |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73534A (en) * | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| US5741908A (en) * | 1996-06-21 | 1998-04-21 | Minnesota Mining And Manufacturing Company | Process for reparing imidazoquinolinamines |
| US7323568B2 (en) * | 2005-12-12 | 2008-01-29 | Chemagis Ltd. | Process for preparing Imiquimod |
-
2006
- 2006-03-20 CA CA2601542A patent/CA2601542C/en not_active Expired - Lifetime
- 2006-03-20 RU RU2007139008/04A patent/RU2007139008A/ru not_active Application Discontinuation
- 2006-03-20 AU AU2006226412A patent/AU2006226412A1/en not_active Abandoned
- 2006-03-20 DK DK06708801.3T patent/DK1879893T3/da active
- 2006-03-20 SI SI200630750T patent/SI1879893T1/sl unknown
- 2006-03-20 US US11/886,726 patent/US8106202B2/en active Active
- 2006-03-20 BR BRPI0609399-0A patent/BRPI0609399A2/pt not_active Application Discontinuation
- 2006-03-20 AT AT06708801T patent/ATE469901T1/de active
- 2006-03-20 PL PL06708801T patent/PL1879893T3/pl unknown
- 2006-03-20 CN CNA2006800092878A patent/CN101146810A/zh active Pending
- 2006-03-20 WO PCT/EP2006/060887 patent/WO2006100226A1/en not_active Ceased
- 2006-03-20 MX MX2007011238A patent/MX2007011238A/es not_active Application Discontinuation
- 2006-03-20 DE DE602006014677T patent/DE602006014677D1/de not_active Expired - Lifetime
- 2006-03-20 JP JP2008502393A patent/JP2008533189A/ja active Pending
- 2006-03-20 PT PT06708801T patent/PT1879893E/pt unknown
- 2006-03-20 EP EP06708801A patent/EP1879893B1/de not_active Expired - Lifetime
- 2006-03-20 ES ES06708801T patent/ES2346687T3/es not_active Expired - Lifetime
- 2006-03-20 KR KR1020077024147A patent/KR20070113309A/ko not_active Withdrawn
-
2007
- 2007-09-18 IL IL186040A patent/IL186040A/en active IP Right Grant
-
2010
- 2010-09-01 CY CY20101100801T patent/CY1111227T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL186040A (en) | 2011-11-30 |
| SI1879893T1 (sl) | 2010-09-30 |
| RU2007139008A (ru) | 2009-04-27 |
| JP2008533189A (ja) | 2008-08-21 |
| BRPI0609399A2 (pt) | 2010-03-30 |
| CN101146810A (zh) | 2008-03-19 |
| EP1879893B1 (de) | 2010-06-02 |
| DK1879893T3 (da) | 2010-09-13 |
| AU2006226412A1 (en) | 2006-09-28 |
| IL186040A0 (en) | 2008-02-09 |
| DE602006014677D1 (de) | 2010-07-15 |
| US20090005566A1 (en) | 2009-01-01 |
| KR20070113309A (ko) | 2007-11-28 |
| CA2601542C (en) | 2012-09-18 |
| PL1879893T3 (pl) | 2010-11-30 |
| CA2601542A1 (en) | 2006-09-28 |
| PT1879893E (pt) | 2010-09-02 |
| ES2346687T3 (es) | 2010-10-19 |
| CY1111227T1 (el) | 2015-06-11 |
| EP1879893A1 (de) | 2008-01-23 |
| WO2006100226A1 (en) | 2006-09-28 |
| US8106202B2 (en) | 2012-01-31 |
| MX2007011238A (es) | 2007-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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