ATE466569T1 - Nasale verabreichung von metoclopramid zur behandlung der gastroparese - Google Patents
Nasale verabreichung von metoclopramid zur behandlung der gastropareseInfo
- Publication number
- ATE466569T1 ATE466569T1 AT01922935T AT01922935T ATE466569T1 AT E466569 T1 ATE466569 T1 AT E466569T1 AT 01922935 T AT01922935 T AT 01922935T AT 01922935 T AT01922935 T AT 01922935T AT E466569 T1 ATE466569 T1 AT E466569T1
- Authority
- AT
- Austria
- Prior art keywords
- gastroparesis
- treatment
- metoclopramide
- nasal administration
- nasal
- Prior art date
Links
- 206010021518 Impaired gastric emptying Diseases 0.000 title abstract 2
- 208000001288 gastroparesis Diseases 0.000 title abstract 2
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004503 metoclopramide Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19318100P | 2000-03-30 | 2000-03-30 | |
| PCT/US2001/010356 WO2001074350A1 (en) | 2000-03-30 | 2001-03-30 | Nasal administration of agents for the treatment of gastroparesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE466569T1 true ATE466569T1 (de) | 2010-05-15 |
Family
ID=22712552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01922935T ATE466569T1 (de) | 2000-03-30 | 2001-03-30 | Nasale verabreichung von metoclopramid zur behandlung der gastroparese |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6770262B2 (de) |
| EP (1) | EP1274414B1 (de) |
| KR (1) | KR20030004361A (de) |
| AT (1) | ATE466569T1 (de) |
| AU (1) | AU2001249684A1 (de) |
| CA (1) | CA2403994C (de) |
| CY (1) | CY1111396T1 (de) |
| DE (1) | DE60142037D1 (de) |
| DK (1) | DK1274414T3 (de) |
| ES (1) | ES2346290T3 (de) |
| PT (1) | PT1274414E (de) |
| WO (1) | WO2001074350A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050137265A1 (en) * | 2003-03-31 | 2005-06-23 | Haley Eugene T. | Rapidly dissolving metoclopramide solid oral dosage and method thereof |
| US20040192781A1 (en) * | 2003-03-31 | 2004-09-30 | Haley Eugene T. | Method of administration for metoclopramide and pharmaceutical formulation therefor |
| US6979562B2 (en) * | 2003-11-18 | 2005-12-27 | Ultra Biotech Limited | Methods and compositions for treating gastroparesis |
| US20050153946A1 (en) * | 2003-12-24 | 2005-07-14 | Collegium Pharmaceuticals, Inc. | Temperature-stable formulations, and methods of development thereof |
| MX2008004267A (es) * | 2008-03-28 | 2009-09-28 | Posi Visionary Solutions Llp | Metoclopramida de liberacion prolongada de 12 horas. |
| MX2008004268A (es) * | 2008-03-28 | 2009-09-28 | Posi Visionary Solutions Llp | Metoclopramida de liberacion prolongada de 24 horas. |
| US20130213393A1 (en) | 2009-12-22 | 2013-08-22 | Evoke Pharma, Inc. | Nasal formulations of metoclopramide |
| EP2376075B1 (de) * | 2008-12-22 | 2015-04-08 | Evoke Pharma, Inc. | Nasale metoclopramid-formulierungen |
| EP2688648B1 (de) | 2011-03-23 | 2016-01-06 | RaQualia Pharma Inc. | 5-ht4-rezeptoragonist als prokinetischer wirkstoff |
| CN103957707A (zh) * | 2011-08-25 | 2014-07-30 | 伊沃克制药公司 | 与女性胃轻瘫有关的症状的治疗 |
| MX373078B (es) | 2014-05-16 | 2020-07-03 | Raqualia Pharma Inc | Agonista del receptor 5-ht4 para gastroparesia. |
| CN104606136A (zh) * | 2015-01-06 | 2015-05-13 | 中国人民解放军军事医学科学院毒物药物研究所 | 甲氧氯普胺鼻腔喷雾剂、其制备方法及用途 |
| EP3554489A4 (de) * | 2016-12-15 | 2020-06-17 | Evoke Pharma, Inc. | Behandlung von mässiger bis schwerer gastroparese |
| EP3681573A4 (de) * | 2017-09-11 | 2021-08-04 | Evoke Pharma, Inc. | Verfahren zur dosierung von intranasalem metoclopramid |
| US11786512B2 (en) | 2019-09-23 | 2023-10-17 | Slayback Pharma Llc | Stable pharmaceutical compositions of dihydroergotamine mesylate |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4624965A (en) | 1984-11-15 | 1986-11-25 | Nastech Pharmaceutical Co., Inc. | Novel method of administering anti-nausea and anti-emetic pharmaceutical agents and novel dosage forms containing same |
| US5578628A (en) * | 1985-06-25 | 1996-11-26 | Glaxo Group Limited | Medicaments for the treatment of nausea and vomiting |
| US4729997A (en) | 1985-10-15 | 1988-03-08 | Nastech Pharmaceutical Co., Inc. | Novel method of administering meclizine type pharmaceutical agents and novel dosage forms containing same |
| FR2640139A1 (fr) | 1988-12-14 | 1990-06-15 | Delagrange Laboratoires | Application de benzamides substitues comme gastromoteurs |
| CH681690A5 (en) | 1990-09-28 | 1993-05-14 | Kali Chemie Pharma Gmbh | New metoclopramide salt compsns. with no additives |
| US5576317A (en) | 1994-12-09 | 1996-11-19 | Pfizer Inc. | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis |
| US5760086A (en) | 1996-03-14 | 1998-06-02 | Ribogene, Inc. | Nasal administration of agents for treatment of delayed onset emesis |
-
2001
- 2001-03-29 US US09/821,139 patent/US6770262B2/en not_active Expired - Lifetime
- 2001-03-30 KR KR1020027013082A patent/KR20030004361A/ko not_active Withdrawn
- 2001-03-30 AT AT01922935T patent/ATE466569T1/de active
- 2001-03-30 PT PT01922935T patent/PT1274414E/pt unknown
- 2001-03-30 ES ES01922935T patent/ES2346290T3/es not_active Expired - Lifetime
- 2001-03-30 CA CA2403994A patent/CA2403994C/en not_active Expired - Lifetime
- 2001-03-30 AU AU2001249684A patent/AU2001249684A1/en not_active Abandoned
- 2001-03-30 DE DE60142037T patent/DE60142037D1/de not_active Expired - Lifetime
- 2001-03-30 EP EP01922935A patent/EP1274414B1/de not_active Expired - Lifetime
- 2001-03-30 WO PCT/US2001/010356 patent/WO2001074350A1/en not_active Ceased
- 2001-03-30 DK DK01922935.0T patent/DK1274414T3/da active
-
2002
- 2002-08-15 US US10/222,077 patent/US20030059374A1/en not_active Abandoned
-
2010
- 2010-08-05 CY CY20101100734T patent/CY1111396T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60142037D1 (de) | 2010-06-17 |
| PT1274414E (pt) | 2010-08-10 |
| US20020065321A1 (en) | 2002-05-30 |
| WO2001074350A1 (en) | 2001-10-11 |
| EP1274414A1 (de) | 2003-01-15 |
| KR20030004361A (ko) | 2003-01-14 |
| US6770262B2 (en) | 2004-08-03 |
| EP1274414B1 (de) | 2010-05-05 |
| DK1274414T3 (da) | 2010-08-30 |
| CA2403994C (en) | 2011-08-23 |
| ES2346290T3 (es) | 2010-10-14 |
| AU2001249684A1 (en) | 2001-10-15 |
| CA2403994A1 (en) | 2001-10-11 |
| CY1111396T1 (el) | 2015-08-05 |
| US20030059374A1 (en) | 2003-03-27 |
| EP1274414A4 (de) | 2007-08-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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