ATE46438T1 - Enterischer ueberzug fuer pharmazeutische verabreichungsformen. - Google Patents

Enterischer ueberzug fuer pharmazeutische verabreichungsformen.

Info

Publication number
ATE46438T1
ATE46438T1 AT83110203T AT83110203T ATE46438T1 AT E46438 T1 ATE46438 T1 AT E46438T1 AT 83110203 T AT83110203 T AT 83110203T AT 83110203 T AT83110203 T AT 83110203T AT E46438 T1 ATE46438 T1 AT E46438T1
Authority
AT
Austria
Prior art keywords
dosage forms
pharmaceutical dosage
enteric coating
powder
making
Prior art date
Application number
AT83110203T
Other languages
English (en)
Inventor
Emanuel Joseph Mcginley
Domingo Custodio Tuason Jr
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Application granted granted Critical
Publication of ATE46438T1 publication Critical patent/ATE46438T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/122—Pulverisation by spraying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
    • C08J2301/08—Cellulose derivatives
    • C08J2301/14—Mixed esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
AT83110203T 1982-11-08 1983-10-13 Enterischer ueberzug fuer pharmazeutische verabreichungsformen. ATE46438T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/440,118 US4518433A (en) 1982-11-08 1982-11-08 Enteric coating for pharmaceutical dosage forms
EP83110203A EP0111103B1 (de) 1982-11-08 1983-10-13 Enterischer Überzug für pharmazeutische Verabreichungsformen

Publications (1)

Publication Number Publication Date
ATE46438T1 true ATE46438T1 (de) 1989-10-15

Family

ID=23747516

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83110203T ATE46438T1 (de) 1982-11-08 1983-10-13 Enterischer ueberzug fuer pharmazeutische verabreichungsformen.

Country Status (13)

Country Link
US (1) US4518433A (de)
EP (1) EP0111103B1 (de)
JP (1) JPS59101428A (de)
AT (1) ATE46438T1 (de)
AU (1) AU563741B2 (de)
CA (1) CA1214992A (de)
DE (1) DE3380590D1 (de)
DK (1) DK168891B1 (de)
ES (1) ES8504654A1 (de)
IE (1) IE55998B1 (de)
MY (1) MY100143A (de)
NO (1) NO161124C (de)
ZA (1) ZA838321B (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895725A (en) * 1987-08-24 1990-01-23 Clinical Technologies Associates, Inc. Microencapsulation of fish oil
US4960814A (en) * 1988-06-13 1990-10-02 Eastman Kodak Company Water-dispersible polymeric compositions
US5025004A (en) * 1988-06-13 1991-06-18 Eastman Kodak Company Water-dispersible polymeric compositions
US5248516A (en) * 1989-12-19 1993-09-28 Fmc Corporation Film-forming composition: method of producing same and use for coating pharmaceuticals and foods and the like
US5043376A (en) * 1990-02-26 1991-08-27 Eastman Kodak Company Liquid-dispersible, polymeric colorant compositions and aqueous dispersions
US5104913A (en) * 1990-02-26 1992-04-14 Eastman Kodak Company Liquid-dispersible, polymeric colorant compositions and aqueous dispersions and process for the preparation thereof
US5578323A (en) * 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5811127A (en) * 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5792451A (en) * 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
CA2160693C (en) * 1993-04-22 2010-03-16 Sam J. Milstein Oral drug delivery compositions and methods
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5380790A (en) * 1993-09-09 1995-01-10 Eastman Chemical Company Process for the preparation of acrylic polymers for pharmaceutical coatings
US5416157A (en) * 1993-09-09 1995-05-16 Eastman Chemical Company Process for improving mechanical shear stability of acrylic enteric polymers
SI0723436T1 (en) * 1994-07-08 2002-02-28 Astrazeneca Ab Multiple unit tableted dosage form i
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
CN1151836C (zh) * 1995-03-31 2004-06-02 艾米斯菲尔技术有限公司 用作传送活性剂的化合物和组合物
US6001347A (en) * 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5820881A (en) * 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US5750147A (en) * 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US6084112A (en) * 1995-09-11 2000-07-04 Emisphere Technologies, Inc. Method for preparing ω-aminoalkanoic acid derivatives from cycloalkanones
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
SE9600072D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
SE9600071D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
SI9720025A (sl) * 1996-03-29 1999-08-31 Emishphere Technologies, Inc. Spojine in sestavki za prenos aktivne snovi
US6375983B1 (en) 1996-06-14 2002-04-23 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US20020182258A1 (en) * 1997-01-22 2002-12-05 Zycos Inc., A Delaware Corporation Microparticles for delivery of nucleic acid
US5939381A (en) * 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) * 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
US5985313A (en) * 1997-10-22 1999-11-16 New York Blood Center, Inc. Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients
US6165493A (en) * 1997-10-22 2000-12-26 New York Blood Center, Inc. "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
US6559158B1 (en) 1997-11-03 2003-05-06 Ur Labs, Inc. Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
US6274591B1 (en) * 1997-11-03 2001-08-14 Joseph F. Foss Use of methylnaltrexone and related compounds
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20050037086A1 (en) * 1999-11-19 2005-02-17 Zycos Inc., A Delaware Corporation Continuous-flow method for preparing microparticles
US20040142475A1 (en) * 2000-06-02 2004-07-22 Barman Shikha P. Delivery systems for bioactive agents
EP1404323B1 (de) * 2001-06-05 2009-10-28 The University of Chicago Verwendung von methylnaltrexon zur behandlung von immunsuppression
US8071133B2 (en) * 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
FR2833493B1 (fr) * 2001-12-18 2005-09-23 Ioltechnologie Production Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
ES2609059T3 (es) 2002-10-01 2017-04-18 Banner Life Sciences, LLC Composición entérica para la fabricación de una pared de cápsula blanda
US20040266806A1 (en) * 2003-04-08 2004-12-30 Sanghvi Suketu P. Pharmaceutical formulation
EP1638607A1 (de) * 2003-04-08 2006-03-29 Progenics Pharmaceuticals, Inc. Kombinationstherapie gegen obstipation mit einem laxativ und einem peripheren opioid-antagonisten
JP2006522817A (ja) * 2003-04-08 2006-10-05 プロジェニックス ファーマシューティカルズ，インコーポレーテッド 過敏性腸症候群を処置するための末梢オピオイドアンタゴニスト、特にメチルナルトレキソンの使用
US20050070501A1 (en) * 2003-09-29 2005-03-31 New York Blood Center, Inc. Water dispersible film
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
CN101137378A (zh) * 2005-01-20 2008-03-05 普罗热尼奇制药公司 甲基纳曲酮和相关化合物治疗术后胃肠功能障碍的用途
US8524731B2 (en) * 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
CN101171010B (zh) * 2005-03-07 2014-09-17 芝加哥大学 阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
AR057325A1 (es) * 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
US20080194611A1 (en) * 2005-06-03 2008-08-14 Alverdy John C Modulation of Cell Barrier Dysfunction
CN101272762B (zh) 2005-09-15 2013-02-06 基酶有限公司 胺聚合物的小袋制剂
US20070148248A1 (en) * 2005-12-22 2007-06-28 Banner Pharmacaps, Inc. Gastric reflux resistant dosage forms
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
US20080129253A1 (en) * 2006-11-03 2008-06-05 Advanced Desalination Inc. Battery energy reclamation apparatus and method thereby
CA2865389A1 (en) 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Crystal forms and uses thereof
JP5461386B2 (ja) * 2007-03-29 2014-04-02 プロジェニックス ファーマシューティカルズ，インコーポレーテッド 末梢オピオイド受容体アンタゴニストおよびその使用
HUE025662T2 (en) * 2007-03-29 2016-04-28 Wyeth Llc Peripheral opioid receptor and antagonists and their uses
WO2009020748A2 (en) 2007-07-16 2009-02-12 Avaxia Biologics, Inc. Antibody therapy for modulating function of intestinal receptors
EP2725035A1 (de) 2007-10-02 2014-04-30 Avaxia Biologics, Inc. Antikörpertherapie zur Verwendung im Verdauungstrakt
US8647626B2 (en) * 2007-10-02 2014-02-11 Avaxia Biologics, Incorporated Compositions comprising TNF-specific antibodies for oral delivery
WO2009099411A1 (en) 2008-02-06 2009-08-13 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
CA2719134C (en) 2008-03-21 2015-06-30 The University Of Chicago Treatment with opioid antagonists and mtor inhibitors
ES2620373T3 (es) 2008-07-01 2017-06-28 University Of Chicago Partículas que contienen un antagonista del receptor de opioides periférico
CA2676881C (en) * 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
NZ599315A (en) 2009-10-15 2014-05-30 Avaxia Biologics Inc Antibody therapeutics with local activity in the digestive tract
US20150366814A1 (en) 2014-06-23 2015-12-24 Banner Life Sciences Llc All-natural enteric soft capsules comprising active ingredients
WO2016061531A1 (en) 2014-10-17 2016-04-21 Salix Pharmaceuticals, Inc. Use of methylnaltrexone to attenuate tumor progression
MX2021013488A (es) 2019-05-07 2021-12-10 Bausch Health Ireland Ltd Formulaciones liquidas de dosis oral de metilnaltrexona.
WO2021224138A1 (en) 2020-05-02 2021-11-11 Bausch Health Ireland Limited Methods of reducing mortality risk in subjects suffering from an underlying disease or condition by administration of methylnaltrexone

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112354C (de) *
US2740723A (en) * 1951-05-08 1956-04-03 Hercules Powder Co Ltd Preparation of finely divided cellulose plastics
US2800463A (en) * 1953-05-14 1957-07-23 Shawinigan Resins Corp Polyvinyl acetate powder and process of making the same
US2843582A (en) * 1954-04-08 1958-07-15 Hercules Powder Co Ltd Preparation of finely-divided cellulose derivatives
US2843583A (en) * 1955-03-03 1958-07-15 Hercules Powder Co Ltd Preparation of finely-divided cellulose derivative compositions
US3725089A (en) * 1961-04-20 1973-04-03 J Zola Small particle dispersion coating composition
AT265523B (de) * 1965-01-26 1968-10-10 Wander Ag Dr A Verfahren zur Herstellung einer Manteltablette mit einem magensaftempfindlichen Wirkstoff im Kern
US3539365A (en) * 1967-02-13 1970-11-10 Fmc Corp Dispersing and stabilizing agent comprising beta-1,4 glucan and cmc and method for its preparation
US3935326A (en) * 1967-06-28 1976-01-27 Boehringer Mannheim G.M.B.H. Process for coating tablets with aqueous resin dispersions
US3629237A (en) * 1968-09-12 1971-12-21 Shinetsu Chemical Co Compositions useful as enteric coatings and method for preparing acid phthalates of cellulose ethers for them
DK132126C (da) * 1970-06-20 1976-05-17 Dynamit Nobel Ag Smeltelige overtreksmasser pa grundlag af glycerider iser tilneringsmidler og pharmaceutiske preparater
DE2140996C3 (de) * 1971-03-19 1980-06-19 Shinetsu Chemical Co., Tokio Verwendung eines Celluloseether esters in Überzugsmitteln fur darmwirksame pharmazeutische Produkte
CH582002A5 (de) * 1972-06-09 1976-11-30 Purdue Research Foundation
US3983263A (en) * 1974-06-27 1976-09-28 General Motors Corporation Powdered acrylic paint composition and method
US4112215A (en) * 1975-03-20 1978-09-05 Rohm Gmbh Copolymeric resin binder powders
US4177177A (en) * 1976-03-26 1979-12-04 El Aasser Mohamed S Polymer emulsification process
US4218433A (en) * 1977-03-03 1980-08-19 Nippon Kayaku Kabushiki Kaisha Constant-rate eluting tablet and method of producing same
GB1584130A (en) * 1978-05-30 1981-02-04 Wyeth John & Brother Ltd Indole derivatives
JPS5535031A (en) * 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
US4330338A (en) * 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
JPS5598120A (en) * 1979-01-16 1980-07-25 Shin Etsu Chem Co Ltd Preparation of drug having enteric coating
US4198390A (en) * 1979-01-31 1980-04-15 Rider Joseph A Simethicone antacid tablet
US4248857A (en) * 1979-08-09 1981-02-03 American Home Products Corporation Sustained release pharmaceutical compositions
JPS5654292A (en) * 1979-10-02 1981-05-14 Tadashi Nakanishi Fermentation treating cell
JPS56104823A (en) * 1980-01-28 1981-08-20 Shin Etsu Chem Co Ltd Enteric coating composition for solid preparation
JPS5855125B2 (ja) * 1980-03-10 1983-12-08 信越化学工業株式会社 固形薬剤用腸溶性コ−テイング剤組成物
US4340582A (en) * 1981-01-15 1982-07-20 Abbott Laboratories Erythromycin base tablets
JPS5973529A (ja) * 1982-10-12 1984-04-25 Sankyo Co Ltd 被覆固形製剤の製造法

Also Published As

Publication number Publication date
IE55998B1 (en) 1991-03-13
ES526783A0 (es) 1985-05-01
EP0111103A2 (de) 1984-06-20
ES8504654A1 (es) 1985-05-01
EP0111103A3 (en) 1985-06-19
DE3380590D1 (en) 1989-10-26
JPS6214530B2 (de) 1987-04-02
NO161124B (no) 1989-03-28
NO834052L (no) 1984-05-09
DK508883D0 (da) 1983-11-07
ZA838321B (en) 1984-06-27
IE832095L (en) 1984-05-08
DK508883A (da) 1984-05-09
AU563741B2 (en) 1987-07-23
DK168891B1 (da) 1994-07-04
US4518433A (en) 1985-05-21
CA1214992A (en) 1986-12-09
JPS59101428A (ja) 1984-06-12
AU2104583A (en) 1984-05-17
EP0111103B1 (de) 1989-09-20
NO161124C (no) 1989-07-05
MY100143A (en) 1990-01-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee