ATE463582T1 - Screening-verfahren zur identifizierung neuer aminoacyl-trna-synthetase-inhibitoren - Google Patents
Screening-verfahren zur identifizierung neuer aminoacyl-trna-synthetase-inhibitorenInfo
- Publication number
- ATE463582T1 ATE463582T1 AT07803072T AT07803072T ATE463582T1 AT E463582 T1 ATE463582 T1 AT E463582T1 AT 07803072 T AT07803072 T AT 07803072T AT 07803072 T AT07803072 T AT 07803072T AT E463582 T1 ATE463582 T1 AT E463582T1
- Authority
- AT
- Austria
- Prior art keywords
- resulting
- trna synthetase
- aminoacyl
- substance
- expression
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/9015—Ligases (6)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06120049 | 2006-09-04 | ||
| PCT/EP2007/059063 WO2008028862A1 (en) | 2006-09-04 | 2007-08-30 | A screening method for identifying new aminoacyl-trna synthetase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE463582T1 true ATE463582T1 (de) | 2010-04-15 |
Family
ID=38606618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07803072T ATE463582T1 (de) | 2006-09-04 | 2007-08-30 | Screening-verfahren zur identifizierung neuer aminoacyl-trna-synthetase-inhibitoren |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8183006B2 (de) |
| EP (1) | EP2064338B1 (de) |
| AT (1) | ATE463582T1 (de) |
| DE (1) | DE602007005820D1 (de) |
| ES (1) | ES2344028T3 (de) |
| WO (1) | WO2008028862A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010081110A1 (en) | 2009-01-12 | 2010-07-15 | Sutro Biopharma, Inc. | Dual charging system for selectively introducing non-native amino acids into proteins using an in vitro synthesis method |
| GB201115793D0 (en) * | 2011-09-13 | 2011-10-26 | Univ Warwick | Screening method |
| KR101711584B1 (ko) * | 2012-12-18 | 2017-03-02 | 재단법인 의약바이오컨버젼스연구단 | 변형된 eprs 단백질의 결정 구조 및 이의 결정화 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5798240A (en) | 1994-09-13 | 1998-08-25 | Cubist Pharmaceuticals, Inc. | Recombinant mycobacterial methionyl-tRNA synthetase genes and methods of use therefore |
| EP1251175B1 (de) * | 2001-04-19 | 2006-11-08 | Institut Pasteur | Methode für die Erweiterung der chemischen Zusammensetzung von Proteinen produziert in vivo unter Verwendung von mutierten Aminoacyl-tRNA-Synthetasen ohne Korrekturfunktion |
-
2007
- 2007-08-30 ES ES07803072T patent/ES2344028T3/es active Active
- 2007-08-30 WO PCT/EP2007/059063 patent/WO2008028862A1/en active Application Filing
- 2007-08-30 EP EP07803072A patent/EP2064338B1/de not_active Not-in-force
- 2007-08-30 US US12/439,814 patent/US8183006B2/en not_active Expired - Fee Related
- 2007-08-30 DE DE602007005820T patent/DE602007005820D1/de active Active
- 2007-08-30 AT AT07803072T patent/ATE463582T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2064338B1 (de) | 2010-04-07 |
| US8183006B2 (en) | 2012-05-22 |
| US20100055719A1 (en) | 2010-03-04 |
| DE602007005820D1 (de) | 2010-05-20 |
| WO2008028862A1 (en) | 2008-03-13 |
| EP2064338A1 (de) | 2009-06-03 |
| ES2344028T3 (es) | 2010-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |