ATE462441T1 - Saposin c und rezeptoren als ziele für die behandlung von gutartigen und bösartigen erkrankungen - Google Patents

Saposin c und rezeptoren als ziele für die behandlung von gutartigen und bösartigen erkrankungen

Info

Publication number
ATE462441T1
ATE462441T1 AT03814232T AT03814232T ATE462441T1 AT E462441 T1 ATE462441 T1 AT E462441T1 AT 03814232 T AT03814232 T AT 03814232T AT 03814232 T AT03814232 T AT 03814232T AT E462441 T1 ATE462441 T1 AT E462441T1
Authority
AT
Austria
Prior art keywords
saposin
cells
prostate
cancer cells
cell
Prior art date
Application number
AT03814232T
Other languages
English (en)
Inventor
Shahriar Koochekpour
Olivier Sartor
Original Assignee
Univ Louisiana State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Louisiana State filed Critical Univ Louisiana State
Application granted granted Critical
Publication of ATE462441T1 publication Critical patent/ATE462441T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT03814232T 2002-12-20 2003-12-18 Saposin c und rezeptoren als ziele für die behandlung von gutartigen und bösartigen erkrankungen ATE462441T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/324,993 US7166691B2 (en) 2002-12-20 2002-12-20 Saposin C and receptors as targets for treatment of benign and malignant disorders
PCT/US2003/040648 WO2004058165A2 (en) 2002-12-20 2003-12-18 Saposing c and receptors as targets for treatment of benign and malignant disorders

Publications (1)

Publication Number Publication Date
ATE462441T1 true ATE462441T1 (de) 2010-04-15

Family

ID=32593623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03814232T ATE462441T1 (de) 2002-12-20 2003-12-18 Saposin c und rezeptoren als ziele für die behandlung von gutartigen und bösartigen erkrankungen

Country Status (8)

Country Link
US (1) US7166691B2 (de)
EP (1) EP1578436B1 (de)
AT (1) ATE462441T1 (de)
AU (1) AU2003301135B2 (de)
CA (1) CA2510313C (de)
DE (1) DE60331951D1 (de)
ES (1) ES2343247T3 (de)
WO (1) WO2004058165A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7834147B2 (en) 2003-04-28 2010-11-16 Childrens Hospital Medical Center Saposin C-DOPS: a novel anti-tumor agent
CA2692171C (en) * 2007-06-22 2019-10-22 Randolph Watnick Methods and uses thereof of prosaposin
GB0718045D0 (en) * 2007-09-14 2007-10-24 Peptcell Ltd Pharmaceutical compound
JP2012508233A (ja) * 2008-11-07 2012-04-05 チルドレンズ ホスピタル メディカル センター 膜貫通薬物送達システムへの適用のためのサポシンｃ、並びに関連のタンパク質及びペプチドの融合性
EP3560509B1 (de) * 2011-12-22 2024-01-31 Children's Medical Center Corporation Aus saposin-a gewonnene peptide und verwendungen davon
US9921224B2 (en) 2013-03-14 2018-03-20 Children's Medical Center Corporation Use of CD36 to identify cancer subjects for treatment
KR101947053B1 (ko) 2013-10-18 2019-02-12 도이체스 크렙스포르슝스첸트룸 전립선 특이적 막 항원（ｐｓｍａ）의 표지된 억제제, 조영제로서의 이의 용도 및 전립선암 치료용 약제
AU2015235978B2 (en) 2014-03-26 2019-08-08 Children's Medical Center Corporation Cyclic prosaposin peptides and uses thereof
WO2017219029A2 (en) 2016-06-17 2017-12-21 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd117+cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326467B1 (en) * 1989-02-23 2001-12-04 Colorado State University Research Foundation Hormone-recombinant toxin compounds and methods for using same
US5576288A (en) * 1989-04-27 1996-11-19 The Salk Institute For Biological Studies Fibroblast growth factor conjugates
US5191067A (en) * 1989-04-27 1993-03-02 The Salk Institute For Biological Studies Fibroblast growth factor conjugates
US5478804A (en) * 1990-09-19 1995-12-26 The Salk Institute For Biological Studies Treatment of tumorigenic pathophysiological conditions with FGF-cytoxic conjugates
US5571787A (en) * 1993-07-30 1996-11-05 Myelos Corporation Prosaposin as a neurotrophic factor
US5700909A (en) * 1993-07-30 1997-12-23 The Regents Of The University Of California Prosaposin and cytokine-derived peptides
US6348194B1 (en) * 1995-11-13 2002-02-19 Ixsys Incorporated Tumor specific internalizing antigens and methods for targeting therapeutic agents
US6271196B1 (en) * 1996-03-05 2001-08-07 Regents Of The University Of Ca Methods of alleviating neuropathic pain using prosaposin-derived peptides

Also Published As

Publication number Publication date
US20040120961A1 (en) 2004-06-24
CA2510313A1 (en) 2004-07-15
EP1578436B1 (de) 2010-03-31
AU2003301135A1 (en) 2004-07-22
EP1578436A4 (de) 2008-02-27
CA2510313C (en) 2011-09-27
ES2343247T3 (es) 2010-07-27
WO2004058165A2 (en) 2004-07-15
DE60331951D1 (de) 2010-05-12
WO2004058165A3 (en) 2005-03-24
EP1578436A2 (de) 2005-09-28
US7166691B2 (en) 2007-01-23
AU2003301135B2 (en) 2008-06-19

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