ATE460931T1 - Erhöhung des knochenwachstums und knochenresorptionsinhibierung - Google Patents

Erhöhung des knochenwachstums und knochenresorptionsinhibierung

Info

Publication number
ATE460931T1
ATE460931T1 AT04292124T AT04292124T ATE460931T1 AT E460931 T1 ATE460931 T1 AT E460931T1 AT 04292124 T AT04292124 T AT 04292124T AT 04292124 T AT04292124 T AT 04292124T AT E460931 T1 ATE460931 T1 AT E460931T1
Authority
AT
Austria
Prior art keywords
bone
independently
inhibiting
nrr
nhr
Prior art date
Application number
AT04292124T
Other languages
English (en)
Inventor
Wen-Mei Fu
Chih-Hsin Tang
Rong-Sen Yang
Che-Ming Teng
Sheng-Chu Kuo
Fang-Yu Lee
Original Assignee
Yung Shin Pharmaceutical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yung Shin Pharmaceutical Ind filed Critical Yung Shin Pharmaceutical Ind
Application granted granted Critical
Publication of ATE460931T1 publication Critical patent/ATE460931T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
AT04292124T 2003-09-03 2004-09-02 Erhöhung des knochenwachstums und knochenresorptionsinhibierung ATE460931T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49969603P 2003-09-03 2003-09-03

Publications (1)

Publication Number Publication Date
ATE460931T1 true ATE460931T1 (de) 2010-04-15

Family

ID=34135362

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04292124T ATE460931T1 (de) 2003-09-03 2004-09-02 Erhöhung des knochenwachstums und knochenresorptionsinhibierung

Country Status (8)

Country Link
US (1) US7160916B2 (de)
EP (1) EP1512401B1 (de)
JP (1) JP2005089457A (de)
KR (1) KR101134053B1 (de)
CN (1) CN100548294C (de)
AT (1) ATE460931T1 (de)
DE (1) DE602004026015D1 (de)
TW (1) TWI336326B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2278519B1 (es) * 2005-09-02 2008-09-16 Fundacion Magar Tratamiento de la acondroplasia por la administracion de dinucleotidos.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2928079B2 (ja) * 1994-02-14 1999-07-28 永信薬品工業股▲ふん▼有限公司 １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途
US7115661B1 (en) * 1999-12-29 2006-10-03 Queen's University At Kingston Methods and compositions for mitigating pain
EA002113B1 (ru) 1996-09-04 2001-12-24 Пфайзер Инк. Производные индазола и их использование в качестве ингибиторов фосфодиэстеразы (фдэ) типа iv и продуцирования фактора некроза опухоли (фно)
DE19642255A1 (de) * 1996-10-14 1998-04-16 Bayer Ag Verwendung von 1-Benzyl-3-(substituierten-hetaryl) -kondensierten Pyrazol-Derivaten
DE19744026A1 (de) * 1997-10-06 1999-04-08 Hoechst Marion Roussel De Gmbh Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
HUP0100330A3 (en) 1997-11-04 2002-03-28 Pfizer Prod Inc Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors, compositions containing them and their use
GB9920566D0 (en) * 1999-08-31 1999-11-03 Univ London Screen for axon viability
YU54202A (sh) 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
DE10054278A1 (de) * 2000-11-02 2002-05-08 Bayer Ag Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Osteoporose
US7049334B2 (en) * 2001-09-14 2006-05-23 Carlsbad Technology, Inc. Enhancement of learning and memory and treatment of amnesia
EP1427707A1 (de) 2001-09-19 2004-06-16 Pharmacia Corporation Substituierte indazol verbindungen zur behandlung von entzündungen
US7211561B2 (en) * 2001-10-12 2007-05-01 Cedars-Sinai Medical Center Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa)
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
TW200409759A (en) * 2002-09-25 2004-06-16 Wyeth Corp Substituted 4-(indazol-3-yl)phenols
AU2004275694B2 (en) * 2003-06-30 2008-03-06 Bizbiotech Co., Ltd. Compounds, compositions and methods

Also Published As

Publication number Publication date
US7160916B2 (en) 2007-01-09
EP1512401A1 (de) 2005-03-09
JP2005089457A (ja) 2005-04-07
CN100548294C (zh) 2009-10-14
TW200510330A (en) 2005-03-16
EP1512401B1 (de) 2010-03-17
KR20050024607A (ko) 2005-03-10
CN1615853A (zh) 2005-05-18
TWI336326B (en) 2011-01-21
KR101134053B1 (ko) 2012-04-13
DE602004026015D1 (de) 2010-04-29
US20050131048A1 (en) 2005-06-16

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Legal Events

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