ATE460666T1 - Verfahren zur bestimmung der aminosäurensequenz von peptiden - Google Patents

Verfahren zur bestimmung der aminosäurensequenz von peptiden

Info

Publication number
ATE460666T1
ATE460666T1 AT08150294T AT08150294T ATE460666T1 AT E460666 T1 ATE460666 T1 AT E460666T1 AT 08150294 T AT08150294 T AT 08150294T AT 08150294 T AT08150294 T AT 08150294T AT E460666 T1 ATE460666 T1 AT E460666T1
Authority
AT
Austria
Prior art keywords
amino acid
peptide
determining
acid sequence
peptides
Prior art date
Application number
AT08150294T
Other languages
English (en)
Inventor
Albert John Roeland Heck
Shabaza Mohammed
Van Breukelen
Nadia Taouatas
Madalina Mihaela Drugan
Original Assignee
Univ Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utrecht Holding Bv filed Critical Univ Utrecht Holding Bv
Application granted granted Critical
Publication of ATE460666T1 publication Critical patent/ATE460666T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
AT08150294T 2008-01-15 2008-01-15 Verfahren zur bestimmung der aminosäurensequenz von peptiden ATE460666T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08150294A EP2081025B1 (de) 2008-01-15 2008-01-15 Verfahren zur Bestimmung der Aminosäurensequenz von Peptiden

Publications (1)

Publication Number Publication Date
ATE460666T1 true ATE460666T1 (de) 2010-03-15

Family

ID=39183025

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08150294T ATE460666T1 (de) 2008-01-15 2008-01-15 Verfahren zur bestimmung der aminosäurensequenz von peptiden

Country Status (5)

Country Link
US (1) US8338122B2 (de)
EP (1) EP2081025B1 (de)
AT (1) ATE460666T1 (de)
DE (1) DE602008000796D1 (de)
WO (1) WO2009090188A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602008000796D1 (de) 2008-01-15 2010-04-22 Univ Utrecht Holding Bv Verfahren zur Bestimmung der Aminosäurensequenz von Peptiden
JP2015527067A (ja) 2012-08-20 2015-09-17 メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト アウフ アクティーン Ｎ末端リシンを包有する組換タンパク質を製造する新規の方法
CN103852513B (zh) * 2012-11-29 2016-01-06 中国科学院计算技术研究所 一种基于hcd与etd质谱图的肽段从头测序方法及系统
EP2939024B1 (de) * 2012-12-26 2021-04-28 Quest Diagnostics Investments Incorporated C-peptid-nachweis mittels massenspektrometrie
CN106170298B (zh) 2013-10-16 2024-01-09 前瞻疗法公司 用于提高抗体稳定性的缓冲液制剂
EP3247718B1 (de) 2015-01-21 2021-09-01 Outlook Therapeutics, Inc. Modulation von ladungsvarianten in einer monoklonalen antikörperzusammensetzung
US20190018928A1 (en) * 2015-12-30 2019-01-17 Vito Nv Methods for Mass Spectrometry-Based Structure Determination of Biomacromolecules
JP7084308B2 (ja) 2016-02-03 2022-06-14 アウトルック セラピューティクス，インコーポレイティド 抗体安定性を増大させるための緩衝液製剤
CN109073655A (zh) * 2016-02-04 2018-12-21 安口生物公司 鉴定和分析蛋白的氨基酸序列的方法
WO2017182651A1 (en) * 2016-04-22 2017-10-26 Medimmune Limited Conjugated protease targeting moieties
CN112601962A (zh) * 2018-08-17 2021-04-02 瑞泽恩制药公司 用于从头蛋白质测序的方法
US11726096B2 (en) 2018-10-04 2023-08-15 Regeneron Pharmaceuticals, Inc. Fast protein sequencing
KR20210091243A (ko) 2018-11-15 2021-07-21 퀀텀-에스아이 인코포레이티드 단백질 시퀀싱을 위한 방법 및 조성물
CA3159362A1 (en) * 2019-10-28 2021-05-06 Quantum-Si Incorporated Methods of single-polypeptide sequencing and reconstruction

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060141632A1 (en) * 2000-07-25 2006-06-29 The Procter & Gamble Co. New methods and kits for sequencing polypeptides
US20040121477A1 (en) * 2002-12-20 2004-06-24 Thompson Dean R. Method for improving data dependent ion selection in tandem mass spectroscopy of protein digests
US7371514B2 (en) 2004-07-16 2008-05-13 Agilent Technologies, Inc. Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry
DE602008000796D1 (de) 2008-01-15 2010-04-22 Univ Utrecht Holding Bv Verfahren zur Bestimmung der Aminosäurensequenz von Peptiden

Also Published As

Publication number Publication date
EP2081025A9 (de) 2009-09-30
DE602008000796D1 (de) 2010-04-22
WO2009090188A1 (en) 2009-07-23
US8338122B2 (en) 2012-12-25
US20100311098A1 (en) 2010-12-09
EP2081025A1 (de) 2009-07-22
EP2081025B1 (de) 2010-03-10

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