ATE460425T1 - Histondeacetylaseinhibitor und verfahren zu dessen herstellung - Google Patents
Histondeacetylaseinhibitor und verfahren zu dessen herstellungInfo
- Publication number
- ATE460425T1 ATE460425T1 AT04746393T AT04746393T ATE460425T1 AT E460425 T1 ATE460425 T1 AT E460425T1 AT 04746393 T AT04746393 T AT 04746393T AT 04746393 T AT04746393 T AT 04746393T AT E460425 T1 ATE460425 T1 AT E460425T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- production
- histone deacetylase
- deacetylase inhibitor
- present
- Prior art date
Links
- 239000003276 histone deacetylase inhibitor Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229940121372 histone deacetylase inhibitor Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 102000003964 Histone deacetylase Human genes 0.000 abstract 2
- 108090000353 Histone deacetylase Proteins 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C07K5/126—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003177298 | 2003-06-20 | ||
| PCT/JP2004/008924 WO2004113366A1 (ja) | 2003-06-20 | 2004-06-18 | ヒストン脱アセチル化酵素阻害剤およびその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE460425T1 true ATE460425T1 (de) | 2010-03-15 |
Family
ID=33534930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04746393T ATE460425T1 (de) | 2003-06-20 | 2004-06-18 | Histondeacetylaseinhibitor und verfahren zu dessen herstellung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7662778B2 (de) |
| EP (1) | EP1640380B1 (de) |
| JP (1) | JP4550738B2 (de) |
| AT (1) | ATE460425T1 (de) |
| DE (1) | DE602004025935D1 (de) |
| WO (1) | WO2004113366A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003211576A1 (en) * | 2002-02-20 | 2003-09-09 | Sueharu Horinouchi | Histone deacetylase inhibitors and process for producing the same |
| US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| JP2007262058A (ja) * | 2006-03-03 | 2007-10-11 | Tokyo Univ Of Science | 糸状菌の分化抑制剤 |
| US8158587B2 (en) | 2006-09-05 | 2012-04-17 | Kyushu Institute Of Technology | Compound having histone deacetylase-inhibiting activity, and pharmaceutical composition comprising the compound as an active ingredient |
| WO2009032352A1 (en) * | 2007-09-09 | 2009-03-12 | University Of Florida Research Foundation | Macrocyclic compounds and methods of treatment |
| WO2009079375A1 (en) * | 2007-12-14 | 2009-06-25 | Georgetown University | Histone deacetylase inhibitors |
| US20110123644A1 (en) * | 2008-04-11 | 2011-05-26 | University Of Florida Research Foundation | Macrocyclic compounds and methods of treatment |
| US9874565B2 (en) * | 2013-06-21 | 2018-01-23 | Dana-Farber Cancer Institute, Inc. | Oncogene associated with human cancers and methods of use thereof |
| CN109912686B (zh) * | 2019-03-13 | 2022-07-05 | 北京大学深圳研究生院 | 一种靶向hdac的稳定多肽类抑制剂及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922837A (en) * | 1995-09-20 | 1999-07-13 | Merck & Co., Inc. | Antiprotozoal cyclic tetrapeptides |
| AU732299B2 (en) * | 1997-09-02 | 2001-04-12 | Japan Energy Corporation | Novel cyclic tetrapeptide derivatives and pharmaceutical use thereof |
| JPH11130795A (ja) | 1997-10-29 | 1999-05-18 | Yamanouchi Pharmaceut Co Ltd | Ｙｍ−１７５２０１物質 |
| CZ20011342A3 (cs) | 1998-10-13 | 2001-09-12 | Fujisawa Pharmaceutical Co., Ltd. | Cyklické tetrapeptidy |
| JP4269041B2 (ja) | 1999-03-02 | 2009-05-27 | 国立大学法人九州工業大学 | 新規な環状テトラペプチド誘導体とその医薬用途 |
| AU6109600A (en) | 1999-07-23 | 2001-02-13 | Merck & Co., Inc. | Apicidin-derived cyclic tetrapeptides |
| US20030078369A1 (en) * | 1999-07-23 | 2003-04-24 | Meinke Peter T. | Apicidin-derived cyclic tetrapeptides |
| JP2001316283A (ja) | 2000-02-28 | 2001-11-13 | Yasushi Kaneda | 遺伝子発現増強剤 |
| CA2317003A1 (en) | 2000-02-28 | 2001-08-28 | Hidenori Nakajima | Gene expression potentiator |
| WO2003057722A2 (en) | 2001-12-28 | 2003-07-17 | Fujisawa Pharmaceutical Co., Ltd. | Cyclic tetrapeptide compound and use thereof |
| AU2003211576A1 (en) | 2002-02-20 | 2003-09-09 | Sueharu Horinouchi | Histone deacetylase inhibitors and process for producing the same |
-
2004
- 2004-06-18 US US10/561,298 patent/US7662778B2/en not_active Expired - Fee Related
- 2004-06-18 DE DE602004025935T patent/DE602004025935D1/de not_active Expired - Fee Related
- 2004-06-18 EP EP04746393A patent/EP1640380B1/de not_active Expired - Lifetime
- 2004-06-18 JP JP2005507289A patent/JP4550738B2/ja not_active Expired - Fee Related
- 2004-06-18 WO PCT/JP2004/008924 patent/WO2004113366A1/ja not_active Ceased
- 2004-06-18 AT AT04746393T patent/ATE460425T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4550738B2 (ja) | 2010-09-22 |
| EP1640380A4 (de) | 2006-08-23 |
| EP1640380B1 (de) | 2010-03-10 |
| US7662778B2 (en) | 2010-02-16 |
| US20070185071A1 (en) | 2007-08-09 |
| JPWO2004113366A1 (ja) | 2007-09-20 |
| WO2004113366A1 (ja) | 2004-12-29 |
| EP1640380A1 (de) | 2006-03-29 |
| DE602004025935D1 (de) | 2010-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |