ATE460405T1 - Antibiotische verbindung - Google Patents

Antibiotische verbindung

Info

Publication number
ATE460405T1
ATE460405T1 AT04757246T AT04757246T ATE460405T1 AT E460405 T1 ATE460405 T1 AT E460405T1 AT 04757246 T AT04757246 T AT 04757246T AT 04757246 T AT04757246 T AT 04757246T AT E460405 T1 ATE460405 T1 AT E460405T1
Authority
AT
Austria
Prior art keywords
antibiotic compound
compound
fermentation
yields
nutrient medium
Prior art date
Application number
AT04757246T
Other languages
English (en)
Inventor
Sheo Bux Singh
Jun Wang
Angela Basilio
Olga Genilloud
Pilar Hernandez
Jose Ruben Tormo
Original Assignee
Merck Sharp & Dohme
Merck Sharp & Dohme De Espana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme, Merck Sharp & Dohme De Espana filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE460405T1 publication Critical patent/ATE460405T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT04757246T 2003-07-24 2004-07-20 Antibiotische verbindung ATE460405T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48986503P 2003-07-24 2003-07-24
PCT/US2004/023780 WO2005009391A2 (en) 2003-07-24 2004-07-20 Antibiotic compound

Publications (1)

Publication Number Publication Date
ATE460405T1 true ATE460405T1 (de) 2010-03-15

Family

ID=34102947

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04757246T ATE460405T1 (de) 2003-07-24 2004-07-20 Antibiotische verbindung

Country Status (9)

Country Link
US (1) US7745644B2 (de)
EP (1) EP1651628B1 (de)
JP (1) JP4538455B2 (de)
CN (1) CN100448863C (de)
AT (1) ATE460405T1 (de)
AU (1) AU2004259014B2 (de)
CA (1) CA2532802C (de)
DE (1) DE602004025946D1 (de)
WO (1) WO2005009391A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2565431C (en) * 2004-05-24 2013-01-15 Merck And Co., Inc. Antibiotic compound produced by fermentation with streptomyces sp.
WO2008032140A1 (en) * 2006-09-11 2008-03-20 Yedir Ouhdouch Antibiotic chemical structure obtained from the strain streptomyces sp. bs46 and its use against methicillin-resistant bacteria
EP2698157B1 (de) 2006-09-22 2015-05-20 Merck Sharp & Dohme Corp. Verfahren zur Behandlung von Fettsäure-Synthese-Hemmern
CN101450915B (zh) * 2007-11-30 2013-01-23 山东轩竹医药科技有限公司 环己烯酮取代的苯甲酸衍生物
US8471043B2 (en) 2008-04-08 2013-06-25 Snu R&Db Foundation Platensimycin derivatives, their intermediates, and process for preparing the same, and new process for preparing platensimycin
KR101064112B1 (ko) 2008-12-12 2011-09-08 서울대학교산학협력단 신규한 플라텐시마이신 유도체와 이의 제조방법 및 플라텐시마이신의 신규한 제조방법
JP2010057390A (ja) * 2008-09-02 2010-03-18 Nikken Seibutsu Igaku Kenkyusho:Kk 検査用具
US8754054B2 (en) 2010-07-09 2014-06-17 Albany Molecular Research, Inc. Antibacterial compounds, methods of making them, and uses thereof
ES2709480T3 (es) * 2013-12-24 2019-04-16 Harvard College Análogos de cortistatina y síntesis y usos de los mismos
JP7032732B2 (ja) * 2018-03-01 2022-03-09 国立大学法人 東京大学 プラテンシマイシンの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH456570A (de) 1965-11-18 1968-07-31 Geigy Ag J R Verfahren zur Herstellung von neuen substituierten Harnstoffderivaten
EP1033130B1 (de) * 1998-07-29 2004-04-21 Taiho Pharmaceutical Company Limited Hemmer der angiogenese und der urokinase produktion und seine medizinische anwendung

Also Published As

Publication number Publication date
EP1651628A2 (de) 2006-05-03
US20080306139A1 (en) 2008-12-11
EP1651628A4 (de) 2008-07-16
AU2004259014A1 (en) 2005-02-03
WO2005009391A3 (en) 2005-10-20
WO2005009391A2 (en) 2005-02-03
EP1651628B1 (de) 2010-03-10
CA2532802C (en) 2013-11-19
DE602004025946D1 (de) 2010-04-22
CA2532802A1 (en) 2005-02-03
AU2004259014B2 (en) 2009-12-17
CN1849313A (zh) 2006-10-18
CN100448863C (zh) 2009-01-07
JP2006528639A (ja) 2006-12-21
JP4538455B2 (ja) 2010-09-08
US7745644B2 (en) 2010-06-29

Similar Documents

Publication Publication Date Title
ATE460405T1 (de) Antibiotische verbindung
AU2003268201A1 (en) Capillary perfused bioreactors with multiple chambers
AP2001002236A0 (en) Macrolide antibiotics.
EP2388333A3 (de) Verfahren zur Herstellung einer organischen Verbindung mit geringem Molekulargewicht in einer Zelle
WO2007024997A3 (en) Methods of increasing production of secondary metabolites
WO2009060835A1 (ja) 新規ユビキリン結合性小分子
AU2003298826A1 (en) Culture chamber for biologicals
ATE353894T1 (de) Acyloxymethylcarbamat-prodrugs von oxazolidinonen
IN2012DN02609A (de)
MXPA03008460A (es) Derivados pesticidas de espinosina.
NL1023790A1 (nl) Farmaceutische samenstellingen met antibiotische activiteit.
TW200732285A (en) Carbonates of fenicol antibiotics
WO2003029195A1 (en) Intermediates for epothilone derivative and process for producing these
ATE376778T1 (de) Bakterielle autolysate
GB0228724D0 (en) Multidimensinal libraries
AU6475600A (en) Antibiotic caprazamycins and process for producing the same
WO2005115400A3 (en) Antibiotic compound
SG148168A1 (en) Genetically modified microorganism and process for production of macrolide compound using the microorganism
CR8162A (es) Piridinylanilides
WO2004004646A3 (en) O-derivatized nocathiacin derivatives
WO2006086012A8 (en) Antibiotic compound
NZ511728A (en) Substances WK-5344A and WK-5344B obtained from microorganisms of the genus Streptomyces
EA199900718A1 (ru) Новые соединения
WO2008024285A3 (en) Antibiotic compound
CA2467249A1 (en) Polyene polyketides, processes for their production and their use as pharmaceuticals

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties