ATE45950T1 - Benzopyrano(4,3,2-cd>indazolverbindungen, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zubereitungen. - Google Patents
Benzopyrano(4,3,2-cd>indazolverbindungen, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zubereitungen.Info
- Publication number
- ATE45950T1 ATE45950T1 AT85304630T AT85304630T ATE45950T1 AT E45950 T1 ATE45950 T1 AT E45950T1 AT 85304630 T AT85304630 T AT 85304630T AT 85304630 T AT85304630 T AT 85304630T AT E45950 T1 ATE45950 T1 AT E45950T1
- Authority
- AT
- Austria
- Prior art keywords
- sec
- carbon atoms
- straight
- chem
- hydroxyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- -1 Benzopyrano[4,3,2-cd]indazole compound Chemical class 0.000 abstract 1
- 101100294102 Caenorhabditis elegans nhr-2 gene Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/38—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. nitrodiphenyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/28—Pyronines ; Xanthon, thioxanthon, selenoxanthan, telluroxanthon dyes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62609084A | 1984-06-29 | 1984-06-29 | |
| EP85304630A EP0172632B1 (de) | 1984-06-29 | 1985-06-28 | Benzopyrano[4,3,2-cd]indazolverbindungen, Verfahren zu ihrer Herstellung und die sie enthaltenden pharmazeutischen Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE45950T1 true ATE45950T1 (de) | 1989-09-15 |
Family
ID=24508903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85304630T ATE45950T1 (de) | 1984-06-29 | 1985-06-28 | Benzopyrano(4,3,2-cd>indazolverbindungen, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zubereitungen. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0172632B1 (de) |
| JP (2) | JPH0662627B2 (de) |
| AT (1) | ATE45950T1 (de) |
| AU (2) | AU572309B2 (de) |
| CA (1) | CA1251450A (de) |
| DE (1) | DE3572664D1 (de) |
| DK (1) | DK162098C (de) |
| ES (1) | ES8707241A1 (de) |
| ZA (1) | ZA854473B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806654A (en) * | 1987-03-23 | 1989-02-21 | Warner-Lambert Company | Processes for the preparation of benzo(chalcogeno)(4,3,2-cd)indazoles and intermediates thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2237629B1 (de) * | 1973-07-16 | 1977-07-08 | Parke Davis & Co | |
| US4026899A (en) * | 1974-09-20 | 1977-05-31 | Parke, Davis & Company | Benzo and benzothiopyranoindazole N-oxides |
| IL69211A (en) * | 1982-07-23 | 1987-01-30 | Warner Lambert Co | Substituted anthra(1,9-cd)pyrazol-6(2h)-ones,their preparation and pharmaceutical compositions containing them |
| IE56749B1 (en) * | 1983-01-06 | 1991-12-04 | Warner Lambert Co | Benzothiopyrano(4,3,2-cd)indazoles,their pharmaceutical compositions and methods for their production |
-
1985
- 1985-06-06 CA CA000483352A patent/CA1251450A/en not_active Expired
- 1985-06-13 ZA ZA854473A patent/ZA854473B/xx unknown
- 1985-06-26 AU AU44188/85A patent/AU572309B2/en not_active Ceased
- 1985-06-27 JP JP60139245A patent/JPH0662627B2/ja not_active Expired - Lifetime
- 1985-06-27 ES ES544641A patent/ES8707241A1/es not_active Expired
- 1985-06-27 DK DK292285A patent/DK162098C/da not_active IP Right Cessation
- 1985-06-28 EP EP85304630A patent/EP0172632B1/de not_active Expired
- 1985-06-28 DE DE8585304630T patent/DE3572664D1/de not_active Expired
- 1985-06-28 AT AT85304630T patent/ATE45950T1/de not_active IP Right Cessation
-
1988
- 1988-03-31 AU AU14105/88A patent/AU594868B2/en not_active Ceased
-
1994
- 1994-02-28 JP JP6029227A patent/JPH0753543A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK292285D0 (da) | 1985-06-27 |
| AU594868B2 (en) | 1990-03-15 |
| ES544641A0 (es) | 1987-07-16 |
| DK292285A (da) | 1985-12-30 |
| JPS6115884A (ja) | 1986-01-23 |
| AU1410588A (en) | 1988-07-14 |
| AU4418885A (en) | 1986-01-02 |
| ZA854473B (en) | 1987-02-25 |
| EP0172632A1 (de) | 1986-02-26 |
| JPH0753543A (ja) | 1995-02-28 |
| JPH0662627B2 (ja) | 1994-08-17 |
| AU572309B2 (en) | 1988-05-05 |
| DE3572664D1 (en) | 1989-10-05 |
| CA1251450A (en) | 1989-03-21 |
| ES8707241A1 (es) | 1987-07-16 |
| DK162098C (da) | 1992-02-24 |
| DK162098B (da) | 1991-09-16 |
| EP0172632B1 (de) | 1989-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |