ATE459423T1 - Methode zur magnetischen trennung - Google Patents
Methode zur magnetischen trennungInfo
- Publication number
- ATE459423T1 ATE459423T1 AT03001933T AT03001933T ATE459423T1 AT E459423 T1 ATE459423 T1 AT E459423T1 AT 03001933 T AT03001933 T AT 03001933T AT 03001933 T AT03001933 T AT 03001933T AT E459423 T1 ATE459423 T1 AT E459423T1
- Authority
- AT
- Austria
- Prior art keywords
- magnetic separation
- separation method
- target substances
- separation column
- entrapment
- Prior art date
Links
- 238000007885 magnetic separation Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000013076 target substance Substances 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/002—High gradient magnetic separation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3601—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit
- A61M1/3603—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit in the same direction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3601—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit
- A61M1/3604—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit in opposite directions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3618—Magnetic separation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
- A61M1/3647—Mode of operation with recirculation of the priming solution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/06—Filters making use of electricity or magnetism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/027—High gradient magnetic separators with reciprocating canisters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0335—Component parts; Auxiliary operations characterised by the magnetic circuit using coils
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/034—Component parts; Auxiliary operations characterised by the magnetic circuit characterised by the matrix elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Hard Magnetic Materials (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- External Artificial Organs (AREA)
- Soft Magnetic Materials (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/394,834 US5705059A (en) | 1995-02-27 | 1995-02-27 | Magnetic separation apparatus |
US08/487,277 US5711871A (en) | 1995-02-27 | 1995-06-07 | Magnetic separation apparatus |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE459423T1 true ATE459423T1 (de) | 2010-03-15 |
Family
ID=23560603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03001933T ATE459423T1 (de) | 1995-02-27 | 1996-01-29 | Methode zur magnetischen trennung |
Country Status (9)
Country | Link |
---|---|
US (3) | US5705059A (de) |
EP (2) | EP0869838B1 (de) |
AT (1) | ATE459423T1 (de) |
AU (1) | AU4766396A (de) |
DE (2) | DE69628584T2 (de) |
DK (1) | DK1308211T3 (de) |
ES (1) | ES2202427T3 (de) |
IL (1) | IL116914A (de) |
WO (1) | WO1996026782A1 (de) |
Families Citing this family (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5770029A (en) * | 1996-07-30 | 1998-06-23 | Soane Biosciences | Integrated electrophoretic microdevices |
US6660159B1 (en) | 1996-06-07 | 2003-12-09 | Immunivest Corporation | Magnetic separation apparatus and methods |
US6790366B2 (en) | 1996-06-07 | 2004-09-14 | Immunivest Corporation | Magnetic separation apparatus and methods |
US6136182A (en) * | 1996-06-07 | 2000-10-24 | Immunivest Corporation | Magnetic devices and sample chambers for examination and manipulation of cells |
WO1997046882A1 (en) * | 1996-06-07 | 1997-12-11 | Immunivest Corporation | Magnetic separation employing external and internal gradients |
US6890426B2 (en) | 1996-06-07 | 2005-05-10 | Immunivest Corporation | Magnetic separation apparatus and methods |
US6074827A (en) | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
FR2758884B1 (fr) | 1997-01-30 | 1999-04-02 | Bio Merieux | Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu |
DE69818650T2 (de) | 1997-03-25 | 2004-08-12 | Immunivest Corp., Wilmington | Gerät und methoden zum einfnag und zur analyse von partikel-einheiten |
US6117100A (en) * | 1997-06-06 | 2000-09-12 | Powers; Kathleen M. | Hemodialysis-double dialyzers in parallel |
US6616623B1 (en) * | 1997-07-02 | 2003-09-09 | Idializa Ltd. | System for correction of a biological fluid |
DE69934449T2 (de) * | 1998-03-12 | 2007-09-27 | Miltenyi Biotech Gmbh | Mikrokolonnen-System für Magnettrennung |
IL124514A (en) * | 1998-05-17 | 2002-02-10 | Davidson Chaim | Method and apparatus for magnetically separating selected particles, particularly biological cells |
US6361749B1 (en) * | 1998-08-18 | 2002-03-26 | Immunivest Corporation | Apparatus and methods for magnetic separation |
US6150182A (en) * | 1998-11-30 | 2000-11-21 | Cassaday; Michael M. | Method for separation of components in a biochemical reaction utilizing a combination of magnetic and centrifugal processes |
AU2601600A (en) * | 1999-01-06 | 2000-07-24 | University Of Medicine And Dentistry Of New Jersey | Method and apparatus for separating biological materials and other substances |
US7364921B1 (en) | 1999-01-06 | 2008-04-29 | University Of Medicine And Dentistry Of New Jersey | Method and apparatus for separating biological materials and other substances |
US6193892B1 (en) | 1999-03-03 | 2001-02-27 | Promega Corporation | Magnetic separation assembly and method |
US6312910B1 (en) | 1999-04-09 | 2001-11-06 | Shot, Inc. | Multistage electromagnetic separator for purifying cells, chemicals and protein structures |
JP2003505703A (ja) * | 1999-07-23 | 2003-02-12 | テプネル・メディカル・リミテッド | 生体分子の単離 |
US6468432B1 (en) | 1999-09-03 | 2002-10-22 | Miltenyi Biotec Gmbh | Methods of modification of selected cells in a magnetic cell separation column |
US7537938B2 (en) * | 2000-04-28 | 2009-05-26 | Monogram Biosciences, Inc. | Biomarker detection in circulating cells |
US6692702B1 (en) | 2000-07-07 | 2004-02-17 | Coulter International Corp. | Apparatus for biological sample preparation and analysis |
US7011852B2 (en) * | 2001-05-07 | 2006-03-14 | Hemogenesis, Llc | Separation of platelets from whole blood for use as a healant |
US8101077B2 (en) * | 2001-05-07 | 2012-01-24 | Sivaprasad Sukavaneshvar | Device for separating platelets from fluid suspensions |
US20030095897A1 (en) * | 2001-08-31 | 2003-05-22 | Grate Jay W. | Flow-controlled magnetic particle manipulation |
AU2002359340A1 (en) * | 2001-10-31 | 2003-05-12 | Ventrigraft Inc | Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo |
US20030099954A1 (en) * | 2001-11-26 | 2003-05-29 | Stefan Miltenyi | Apparatus and method for modification of magnetically immobilized biomolecules |
US20030170686A1 (en) * | 2001-12-07 | 2003-09-11 | Rene Hoet | Method and apparatus for washing magnetically responsive particles |
US6889468B2 (en) | 2001-12-28 | 2005-05-10 | 3M Innovative Properties Company | Modular systems and methods for using sample processing devices |
EP1540348A4 (de) | 2002-08-27 | 2006-10-11 | Stemcells California Inc | Angereicherte stammzellen- und vorläuferzellpopulationen des zentralen nervensystems und identifizierungs-, isolierungs- und anreicherungsverfahren für solche populationen |
CN1230531C (zh) * | 2002-12-09 | 2005-12-07 | 清华大学 | 从样品中分离细胞粒子的方法 |
CN1223680C (zh) * | 2002-12-10 | 2005-10-19 | 清华大学 | 扩增靶细胞或病毒的核酸的方法 |
US20040142384A1 (en) * | 2003-01-16 | 2004-07-22 | Cohen Barb Ariel | Magnetic separator |
EP1633486A1 (de) * | 2003-06-09 | 2006-03-15 | Dow Corning Corporation | Magnetabscheider |
US7402398B2 (en) | 2003-07-17 | 2008-07-22 | Monogram Biosciences, Inc. | Measuring receptor homodimerization |
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US20050130177A1 (en) | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
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US20050266394A1 (en) * | 2003-12-24 | 2005-12-01 | Massachusette Institute Of Technology | Magnetophoretic cell clarification |
US20050142571A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using solid phase material |
US7939249B2 (en) | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
US20050142570A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent |
US7727710B2 (en) | 2003-12-24 | 2010-06-01 | 3M Innovative Properties Company | Materials, methods, and kits for reducing nonspecific binding of molecules to a surface |
CA2839092C (en) * | 2004-08-03 | 2018-04-03 | Becton, Dickinson And Company | Use of magnetic material to direct isolation of compounds and fractionation of multipart samples |
JP4999103B2 (ja) | 2004-10-27 | 2012-08-15 | セフィード | 閉鎖系の多段階核酸増幅反応 |
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TWI304746B (en) | 2006-12-29 | 2009-01-01 | Ind Tech Res Inst | Magnetic separation device |
WO2008103265A2 (en) | 2007-02-16 | 2008-08-28 | The Brigham And Women's Hospital, Inc. | Methods of using ledgf/p75 |
WO2008130618A1 (en) * | 2007-04-19 | 2008-10-30 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for separating particles, cells, molecules and particulates |
US7837379B2 (en) | 2007-08-13 | 2010-11-23 | The Charles Stark Draper Laboratory, Inc. | Devices for producing a continuously flowing concentration gradient in laminar flow |
DE102007043281A1 (de) | 2007-09-11 | 2009-05-28 | Sebastian Dr. med. Chakrit Bhakdi | Vorrichtung, Materialien und Verfahren zur Hochgradientenmagnetseparation biologischen Materials |
KR100912530B1 (ko) * | 2007-11-13 | 2009-08-18 | 한국전자통신연구원 | 일회용 다층형 혈장 분리 필터 소자 |
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- 1995-06-07 US US08/478,512 patent/US5691208A/en not_active Expired - Lifetime
- 1995-06-07 US US08/487,277 patent/US5711871A/en not_active Expired - Lifetime
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1996
- 1996-01-26 IL IL11691496A patent/IL116914A/xx not_active IP Right Cessation
- 1996-01-29 EP EP96903650A patent/EP0869838B1/de not_active Expired - Lifetime
- 1996-01-29 EP EP03001933A patent/EP1308211B1/de not_active Expired - Lifetime
- 1996-01-29 DK DK03001933.5T patent/DK1308211T3/da active
- 1996-01-29 ES ES96903650T patent/ES2202427T3/es not_active Expired - Lifetime
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- 1996-01-29 AT AT03001933T patent/ATE459423T1/de active
- 1996-01-29 DE DE69628584T patent/DE69628584T2/de not_active Expired - Lifetime
- 1996-01-29 DE DE69638141T patent/DE69638141D1/de not_active Expired - Lifetime
- 1996-01-29 AU AU47663/96A patent/AU4766396A/en not_active Abandoned
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DK1308211T3 (da) | 2010-06-14 |
EP1308211B1 (de) | 2010-03-03 |
DE69628584D1 (de) | 2003-07-10 |
IL116914A (en) | 2000-12-06 |
US5705059A (en) | 1998-01-06 |
EP0869838B1 (de) | 2003-06-04 |
EP1308211A3 (de) | 2003-06-04 |
DE69628584T2 (de) | 2004-05-13 |
EP0869838A1 (de) | 1998-10-14 |
WO1996026782A1 (en) | 1996-09-06 |
DE69638141D1 (de) | 2010-04-15 |
AU4766396A (en) | 1996-09-18 |
EP1308211A2 (de) | 2003-05-07 |
US5691208A (en) | 1997-11-25 |
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